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《World Science and Technology》 2001-02
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Synergism Factors of Material Base in Compound Prescription of Traditional Chinese Medicine

Yan Yongqing (China Pharmaceutical University Nanjing 210009)  
This paper places its emphasis on the viewpoint that some changes of chemical constituents are of synergism factors in compound prescription of the traditional Chinese medicine, a viewpoint which is put forward according to the relationship between the changes of chemical constituents and pharmacological activities in compound prescription. Since quite few studies in this field have been reported and furthermore the existing such studies are not penetrating, the following six synergism factors can only be summed up on the basis of the changes of some material bases which have already discovered up to now.1. The hydrolysis and transformation among the chemical constituents stimulate the changes of some chemical constituents in quantity or quality;2. Some chemical constituents help increase the dissolution rate of active constituents and their content in the preparation;3. The change of some chemical constituents decreases the toxicity of the main constituents of the compound prescription;4. Some chemical constituents may form a complex compound;5. New compositions may possibly come into being in the decocting process of compound prescription;6. Some influences may occur on the inorganic constituents of compound prescription in its decocting process.
【CateGory Index】: R289.1
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