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《世界科学技术》 2006-03
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Systematic Separation and Preparation of Standard multi-component Collectives from Traditional Chinese Medicine

Xiao Yuansheng Xu Qing Jin Yu Xue Xingya Zhang Feifang Liang Xinmiao (Dalian Institute of Chemical physics,Chinese Academy of Sciences,Da Lian 116023,China)  
Focusing on polar components,similar compounds,homologue components and trace compounds in Traditional Chinese Medicine (TCM),novel strategies and material are developed for systematic separation and characterization of standard multi-component collectives from TCM.Solid phase for hydrophilic interaction chromatography is devel- oping to separate polar components,resin-combination technique is suitable for similar compounds collection,multi- molecular imprinting technology is using to extract homologue components,and differential enriched strategy is ap- plied to afford trace compounds.Also,multi modes and columns chromatography as well as their coupled technolo- gies are applied to prepare standard compounds for library construction.All these works will elucidate the chemical constitution in TCM.
【Fund】: 中国科学院知识创新工程重要方向项目(KGCX2-SW-213)基于现代理论和技术的复方中药系统研究;; 国家自然科学基金重点项目(20235020)中药药效组分的指纹图谱分析的方法研究
【CateGory Index】: R284
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