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《World Journal of Integrated Traditional and Western Medicine》 2006-02
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Experimental Study of Stimulating Effect of Traditional Chinese Drugs on Nerves Regeneration

ZHU Tai - yong, ZHAO Cui - ping (Henan Luoyang Orthopaedic Institute, Luoyang,Henan471002,China)  
Objective; To study the stimulating effect of traditional Chinese drugs(TCD) on the and regeneration of damaged nerves. Methods; The effects of TCD on the growth of ganglion was observed by in - vitro culture with the subjects of dorsal ganglion in chick embryo and common peroneal nerve in rat, which were divided randomly into blank group and experimental groups with different drug concentration. The regeneration of common peroneal nerve was observed with pathomorphology and nerve electrophysiology technology. Results:Compared with the blank group, the length of nerve fibre in the experimental groups of Radix Ginseng, Radix Astragali, Herba Epimedii, Pheretima, Cornu Cervi Pantotrichum, Rodix Codonopsis etc. were longer(P0.05,P0.01); in the groups of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Drynariae, Semen Persicae and Radix Dipsa-ci were not obviously different(P 0. 05) ; in the groups of Flos Carthami and Radix Achyranths Bidentatae were shorter (P0.05) ; in the groups of Semen Strychni was longer when the concentration was lower 0. 025 % (P0. 05) and shorter when over0. 05% (P0. 05) and in the group of JiaWei BuYang HuanWu Tang the amount of myelin sheath cells increased and the cells was density, and the nerve conduction was improved its recover. The length of the nerve in the group of Herba Epimedii was related to stimulation of the drug( P 0. 05). Conclusions: TCDis effective to regeneration of nerve, and in proper concentration, TCD can promote nerve regeneration.
【Fund】: 国家中医管理局青年科学基金项目 NO:18813
【CateGory Index】: R285
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