Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《World Journal of Integrated Traditional and Western Medicine》 2007-12
Add to Favorite Get Latest Update

Effect of Compound Jiao Gu Lan Medicines on Memory and Brain Monoamine Oxidase Activity of Mice

Deng Jiagang,Du Zhengcai,Hao ErweiGuangxi Traditional Chinese Medical University,Nanning Guangxi 530001  
Objective:To study the proportions of ingredients in Jiao Gu Lan(绞股蓝Gynostemma Pentaphyllum)prescriptions in order to explore the mechanism of compound Jiao Gu Lan medicines.Methods:Experiment(1):The decoction of Prescription A(Jiaogulan+XX,1∶1),Prescription B(Jiaogulan+XX,2∶1),Prescription C(Jiaogulan+XX,3∶1),Prescription D(Jiaogulan+XX+Shi Chang Pu(石菖蒲 Rhizoma Acori Graminei),2∶1∶1),and Prescription E(Jiaogulan+XX,2∶1)+ Bing Pian(冰片Borneolum Syntheticum)was given to five groups of mice respectively through gavage for 5 days.The models were made with haloperidol.The step-down test was done to observe the effect of different prescriptions on memory of mice.Experiment(2):The high and low doses of Shi Chang Pu volatile oil and compound Jiao Gu Lan medicines were given to aging mice respectively for 10 days.The brain protein content and monoamine oxidase(MAO-B)activity were detected.Results:Experiment(1):In the step-down test,compared with the model group,the difference in Prescription B and D groups was significant(P0.05)Experiment(2):Compared with the blank group,the difference of effect of high and low doses of compound Jiao Gu Lan medicines on brain protein contents and MAO-B activity of aging mice was significant(P0.01).Conclusion:(1)The effect of proportion of ingredients in Prescription D was the best and Prescription B was the second.(2)The compound Jiao Gu Lan decoction (Jiao Gu Lan +XX,2∶1)can significantly increase the brain protein content and reduce the MAO-B activity of aging mice.
【Fund】: 第18次中泰科技合作联委会资助项目(No:18-505J);; 广西科技厅基金资助项目(No:0630004-7B34)
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 ;复方绞股蓝益智颗粒急性毒性与慢性毒性实验研究[J];Contemporary Medicine;2012-19
2 DU Zheng-cai,DENG Jia-gang(Guangxi Traditional Chinese medical University,Nanning 530001,China);Effect of Compound Jiaogulan Yizhi Granules for Improving Memory in Mice[J];Chinese Journal of Experimental Traditional Medical Formulae;2012-15
3 ZHOU Wei-Hua,TAN Li-Ming,MI Chang-Zhong,et al. Jishou University School of Medicine,Jishou 416000,Hunan,China;Effects of gypenosides on the hippocampal cholinergic system in D-galactose induced Alzheimer's disease in mice[J];Chinese Journal of Gerontology;2012-22
Chinese Journal Full-text Database 3 Hits
1 DENG Jia-gang,HAO Er-wei,GUO Hong-wei,LIU Jun-hui(Guangxi University of TCM,Nanning 530001,China);Analysis of drug law of compound prescription in treating Alzheimer disease[J];Shandong Journal of Traditional Chinese Medicine;2007-06
2 Mu Junxia,Li Xinyi1.Shanxi college of TCM,Taiyuan,Shanxi 030024,China2.The First Hospital of Shanxi Medical University,Taiyuan,Shanxi 030001,China;Effect of Yuanzhi on Learning and memory and AchE Activity of Model Rats with Alzheimer's disease[J];World Journal of Integrated Traditional and Western Medicine;2007-01
3 LIU Jie-shu,HUANG Li-ya(School of Medicine,Hubei Institute of Nationality,Enshi 445000,China);The Experimental Research and Comparative Analyses of Anti-oxidase Expression to Rat with Alzheimer Disease Enhanced by Radix Ophiopongonis and Radix Polygonummultiflorum[J];Lishizhen Medicine and Materia Medica Research;2007-06
Chinese Journal Full-text Database 10 Hits
1 SUN Zhi guang\+1, ZHAO Wan zhou\+2, LU Yin\+2, TANG Ling fang\+3, ZHANG Zhen ling\+3, ZHANG Shi wei\+2 (1. Department of Digestion, Hospital of TCM of Jiangsu Province, Nanjing 210029; 2. College of Traditional Chinese Herbs, Nanjing University of T;ANTIMUTAGENIC EFFECT OF PROCYANIDINS FROM VITIS VINIFERA SEED IN SALMONELLA TEST[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-03
2 LI Jia-lin,HAI Chun-xu ,LIANG Xin,LIU Rui,WANG Peng (Department of Toxicology,Fourth Military Medical University,Xi‘an710032,Shaanxi,China);Effect of Rhodiola on the Peroxidative Damage Model in Microsomes[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-02
3 HONG Zhen-feng,CHEN Yan-hua,ZHOU Jian-heng,LI Tian-jiao (Department of Traditional and Western Medicines, Fujian College of TCM, Fuzhou,350003,Fujian,China);Experimental Study of Achillea Millefolium L.Extract on Hepatic Injury and Chronic Hepatic Fibrosis[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-01
4 PEI Hai-long et al (Academy of Life Science,Northwest University,Xian,Shaanxi 710069 );Determination on Isopropyl Salicylate Anti-bacterial Activity in vitro[J];Journal of Anhui Agricultural Sciences;2008-34
5 CHEN Xiao-ling et al(Academy of Life Science,Northwest University,Xian,Shaanxi 710069);Determination of Ethyl Salicylate Anti-bacterial Activity in vitro[J];Journal of Anhui Agricultural Sciences;2009-02
6 ZHANG Lin-lin et al(College of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu 730070);Effects of Traditional Chinese Medicine Preparation "Like" on Anti-diarrhea of Mice[J];Journal of Anhui Agricultural Sciences;2009-02
7 CHEN Hong et al (College of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu 730070);Bacteriostatic Test in vitro of Chinese Herbal Medical Compounds against Enteric Pathogenic Bacteria in Livestock and Poultry[J];Journal of Anhui Agricultural Sciences;2009-13
8 XING Yan-mei et al (College of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu 730070);Preparation and Pharmacological Effect of Shuangshen Perfusate[J];Journal of Anhui Agricultural Sciences;2009-13
9 ZHANG Tie et al(College of Chinese Veterinary Medicine,Hebei Agricultural University,Dingzhou,Hebei 073000);Research on the Influence of Cerium Nitrate on the Non-specific Immune Function of Mice[J];Journal of Anhui Agricultural Sciences;2010-03
10 HUANG Xiu-qi (Shangqiu Vocational and Technical College,Shangqiu,Henan 476000);Research on the Defervescence Function of Artemisia apiacea Hance[J];Journal of Anhui Agricultural Sciences;2010-09
China Proceedings of conference Full-text Database 10 Hits
1 NIE Li-rong ZHENG Shu-ming QIU Deng-gao Fish Breeding and Healthy Culture Research Center,Southwest University,Chongqing 402460;Antibacterial Experiment of 12 Chinese herbs active ingredient on 3 bacteria from the Aquatic Products in Vitro[A];[C];2010
2 HAN Lihua (Henan Hospital of TCM,zhengzhou 450008,Henan,China);Study of Lvfukang Capsules on Experimental Arrhythmia Models Induced by Coronary Artery Ligation in Dog[A];[C];2009
3 CHU Mei-na~1,ZHU Yi~2,Yang Jia~1 (1.Chongqing Univercity of Medical Sciences,Chongqing 400016,China.2.Hainan Provincial Institute for Drug Control,Haikou 570216,China);Analgesic and Anti-inflammatory Effects of Total Alkaloids from Stephania hainanensis H.S.Lo et Y.Tsoong and it's Acute Toxicity Study[A];[C];2010
4 Pan Hua-Xin, Wang Pei-Xxun, Zhou Lian, Cao Liu-Ying, Liang Rui-Yan (Immunological Laboratory of Clinical Pharmacology Institute, Guangzhou University of TCM. Guangzhou 510405. China);Comparison of anti-inflammatory and immunosuppress effects of two kind of tablets of tripterygium wilfordii polyglycosidium[A];[C];2006
5 WENG Yan~1,CHEN Wu~1,ZHOU Hong-liang~2,WANG Hai-dan~2 1 Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210036,China; 2 Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;Study on Multiple Pharmacodynamics index Evaluation for Extraction process of Dog Penis in Wubie Granules[A];[C];2010
6 ;小儿解热栓的药理筛选[A];[C];2006
7 GuoZhong Medical College of Northwest University for Nationalities Lanzhou 730030;Protective effects of YiGanBuGanTang on CCL_4 injured hepatic in rats[A];[C];2006
8 Lai Xiao-ping, Chen Jian-nan, Ye Mu-rong, Hou Shao-zhen, Li Geng- (Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405 );The therapeutic Effect of Isodon lophanthoides var.gerardianus (Benth.) H.Hara on liver-injured animal models[A];[C];2006
9 XING Mao1 ,WANG Qin2 ,YI Mei-tong2 ,AO Li2(1.Dept of Pharmacy; Xinqiao Hospital; Third Military Medical University; Chongqing 400037,China; 2. Dept of Drug Research; Chongqing Hospital of Traditional Chinese Medicine; Chongqing 400020,China );Dose-Effect Relationship of Analgesic and Anti-inflammatory activities of Yugu Capsules[A];[C];2010
10 LI Ke-Hua SHI Dong-Jie LIU Guang-Fen WANG Qing-Chuan (Fujiang Medical University, Fuzhou 350004, China);Effects of Eclipta prostrata on the inflammation induced by the Naja atra venom and the toxicity of venom per se and its cytotoxin[A];[C];2005
Chinese Journal Full-text Database 10 Hits
1 ZHAO Peng et al(College of Pharmacy,ShaanXi University of Chinese Medicine,Xianyang,Shaanxi 712046);Study on Optimization for Ultrasonic Wave Extraction of Polysaccharide from Gynostemma pentaphyllum[J];Journal of Anhui Agricultural Sciences;2009-18
2 LIU Xia,WANG Ping-jun,Xu Fu-xin (The Frist People's Hospital of Wuhu,Anhui Wuhu 241000,China);STUDY ON GYPENOSIDES INHIBITING NEOPLASM GROWTH AND ELEVATING IMMUNOLOGICAL FUNCTION IN LEWIS LUNG CANCER OF MICE[J];Journal of Anhui Traditional Chinese Medical College;2001-01
3 Y.C.KONG, S.W.TSAO, M.E.SONG, M.H.NG.(Department of Biochemistry, and Anatomy, The Chinese Univcrsity of Hong Kong, Shatin, Hong Kong; and Department of Microbiology, University oj Hong Kong, Poklulam Road, Hong Kong)LIN ZHEFU(Department of Biology, Guangzhou, Guangdong, PRC);POTENTIATION OF MITOGENIC RESPONSE BY EXTRACTS OF THE SWIFTLET'S (APUS) NEST COLLECTED FROM HUAI-JI[J];Acta Zoologica Sinica;1989-04
4 QIAO De-cai,HOU Li-juan(Physical Education and Sport College,Beijing Normal University,Beijing 100875,China);Effects of Exercise-induced Fatigue on the Expression of BDNF and GFAP of Rats' Hippocampus and Striatum[J];Journal of Beijing Sport University;2007-06
6 ;丙烯酰胺安全性毒理学评价[J];Contemporary Medicine;2009-18
7 HOU De-ren, YANG Qi-dong, ZHOU Lin, et al. Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China;Effect of Polygonum Multiflorum Thunb on Learning-memory Ability in Rats with Alzheimer Disease and Its Probable Mechanism[J];Journal of Chinese Physician;2004-03
8 LI Tuo,ZHAO Zhong-xin Department of Neurology,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;β-amyloid and Alzheimer disease:recent progress[J];Academic Journal of Second Military Medical University;2010-10
9 YUAN Zhen-yun,JIANG Xiang-ming,WANG Ming-wei,GU Ping,YANG Xiu-fen,SU Guan-li,YANG Tao,LI Bin First Hospital of Hebei Medical University,Brain Aging and Cognitive Neuroscience Laboratory of Hebei Province,Shijiazhuang 050031,Hebei,China;Effects of voluntary exercise on learning ability,memory and hippocampus growth-associated protein 43 expression in senescence-accelerated prone mouse[J];Academic Journal of Second Military Medical University;2012-01
10 DAI Su-fang 1,GAO Xi 2,XU Hong 1 (1.Experimental Room of Functionology,Dalian Medical University,Dalian 116027,China; 2.Department of Physiology);The effects of Yi Zhi Chong Ji on treatment of dysmnesia in mice[J];Journal of Dalian Medical University;2002-01
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 FENG Jing-han1,CAI Bao-chang2,GUO Wei-feng1,HE Yuan-yuan2(1.The First Medical College,Nanjing University of Chinese Medicine,Nanjing,210046,China;2.School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing,210046,China);Development of Experiment on Treating Alzheimer's Disease with Traditional Chinese Medicine[J];Journal of Nanjing University of Traditional Chinese Medicine;2012-04
2 ;Advances in pharmacological effects of Gypenosides[J];Journal of Jilin Medical College;2015-02
3 PENG Wen-jie;WU Da-hua;Hu'nan University of Chinese Medicine;;The Influence of the Traditional Chinese Medicine to the Central Cholinergic System of Alzheimer's Disease[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2015-07
4 LUO Li-hua;YANG Chang-lin;DU Peng;ZHANG Lin;WANG Ruo-yong;LI Tong;MU Hui-ling;Institute of Aviation Medicine,Air Force;Northeast Forestry University;;Effect of the compound preparation on improving the memory of mice[J];Science and Technology of Food Industry;2015-18
5 DU Zheng-cai1,DENG Jia-gang2*(1.Centre for Drug Research and Development of Guangxi Traditional Chinese Medicine University, Nanning 530001,China;2.Key Laboratory of Efficacy of Chinese Medicine of Guangxi,Nanning 530001,China);Clinical Observation of Compound Jaogulan Granules on Memory Improvement in Human[J];Chinese Journal of Experimental Traditional Medical Formulae;2012-12
6 LI Jian-ying;LI Xu-fa;Sirio Pharma Co.,Ltd of Guangdong;;Orthogonal Test for Optimization of Extraction Process of Gynostemma Pentaphylla Soft Gel[J];Pharmacy Today;2014-02
7 HOU Xue-qin;WEI Ren-rong;ZHANG Yu;GAO Wen-bin;YAN Rong;WANG Qi;Guangzhou University of Chinese Medicine;;Chinese Herbal Formula Intervention on Alzheimer Animal Model Systematic Review Based on Documental Analysis[J];Chinese Journal of Experimental Traditional Medical Formulae;2015-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Chen Wansheng,Fan Wei,Yang Genjin,Qiao Chuanzhuo,Chen Haisheng,Yuan Yuan(Department of Pharmacognosy, College of Pharmacy,Second Military Medical University,Shanghai, 200433);Studies on the chemical constituents of Radix Polygoni multiflori Preparata[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1999-07
2 SONG Shi jun 1,LI Fang fang 2* ,YUE Hua 1,YIN Zhi wei 2 (1.Department of Physiology,the School of Basic Medical Sciences,Hebei Medical University, Shijiazhuang 050017, China;2.Department of Biochemistry, the School of Basic Medical Sciences, Hebei Medical University, Shijiazhuang 050017, China);STUDY ON THE ANTI-AGING EFFECTS OF RADIX POLYGONUM MULTIFLORUM[J];Journal of Hebei Medical University;2003-02
3 WANG Fa-wei 1, WANG Zhi-kuan 1, JIANG Nan 2, TONG Zhan-qi 1, TIAN Jia-he 1, LIU Yi 1,YIN Da-yi 1(1.PLA General Hospital,Beijing 100853,China; 2. Department of Traditional Chinese Medicine of Peking Union Medical College Hospital,Beijing 100730);Clinical study on the effect of Shenlong decoction on vascular dementia[J];Academic Journal of Pla Postgraduate Medical School;2005-02
4 Mu Junxia,Li Xinyi (Shanxi College of TCM,Taiyuan Shanxi 030024);Effect of Shudihuang,Gouqi,Shouwu and Wuweizi on Intracerebral Free Radical Injury of Model Rats with Alzheimer's Disease[J];Journal of Shanxi College of Traditional Chinese Medicine;2006-05
5 Shanghai University of Traditional Chinese MedicineLIN XiaoZHOU Qiang-fengXU De-sheng;Research Progress of the Pharmacological Actions of Ophiopogon Root[J];Shanghai Journal of Traditional Chinese Medicine;2004-06
6 Shi Ganggang, Zhuang Xuexuan, Chen Jinxiang, Lin Lngping(Department of Pharmacology, Shantou University Medical College, 515031);A Convenience Model of Parkinson's Disease in Mice[J];JOURNAL OF SHANTOU UNIVERSITY MEDICAL COLLEGE;1999-01
7 QIU Yue; DU Guan-Hua; QU Zhi-Wei;ZHANG Jun-Tian(Department of Pharmacology,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100050);Protective effects of ginsenoside on the learning and memory impairment induced by transient cerebral ischemia-reperfusion in mice[J];CHINESE PHARMACOLOGICAL BULLETIN;1995-04
8 JIANG Yong, TU Peng fei (Department of Natural Medicines, School of Pharmaceutical Sciences, Beijing University, Beijing 100083, China);Progress in studies on Polygala tenuifolia[J];Chinese Traditional and Herbal Drugs;2001-08
9 Li Bin, et al (Beijing Geriatric Clinical and Research Center);Behavioral Comparison Among Three Animal Models Mimicking Alzheimer's Disease[J];ACTA LABORATORIUM ANIMALIS SCIENTIA SINICA;1999-01
10 Miao Jianting,You Guoxiong, Wang Zhejin. Department of Neurology,Tangdu Hospital, The 4th Military Medical University,Xi'an 710038;A study of the relationship between hypomnesia and cholinergic neurons of hippocampus in vascular dementic rats[J];CHINESE JOURNAL OF CERIATRICS;1997-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved