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《World Journal of Integrated Traditional and Western Medicine》 2008-10
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Impacts of Kai Yu Qing Re Therapy on Dose of Hypoglycemic Drugs in Obese Patients with Type 2 Diabetes Mellitus

SU Hao,TONG Xiao-lin,LIAN Feng-mei,LIU Xia,ZHAI Yi (Guang An Men Hospital,China Academy of Chinese Medical Sciences,Beijing 100053)  
Objective:To observe the impacts of Kai Yu Qing Re therapy(for removing stagnation and reducing heat)on dose of western hypoglycemic drugs in obese patients with type 2 diabetes mellitus. Methods:The retrospective investigative statistical method and SPSS12.0 statistic software package were applied to analyze the data and assess the concrete determined values and their changes before and after treatment for 258 obese patients with type 2 diabetes mellitus. Results:After the treatment with Kai Yu Qing Re therapy,of 258 cases,the dose of hypoglycemic drug was reduced in 88 cases,no change in 139 cases,increased in 13 cases and the medication was altered in 18 cases. With the same treatment plan,The fasting plasma glucose(FPG)and 2 h postprandial glucose(2 hPG)after treatment were reduced compared with those before treatment,indicating significant difference(P0.01). In the cases with dose reducing for ≤3 months,no significant difference presented in FPG and 2 hPG before and after treatment(P0.05);for 4~6 months and 6 months,the significant difference presented in comparison(P0.01). Conclusion:Kai Yu Qing Re therapy can reduce effectively FPG and 2 hPG in the condition of same dose administration of western hypoglycemic drugs,and can still maintain the original PG in the condition of reduced dose administration of original western drugs;moreover,the therapy can reduce PG and apparently decrease the dose of insulin.
【Fund】: 北京市中医局基金资助项目(No.GG2007-036)
【CateGory Index】: R587.1;R589.2
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