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《World Journal of Integrated Traditional and Western Medicine》 2011-03
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Clinical Observation of Prurigo Nodularis Treated with Autohemotherapy Combined with Desloratadine and Triamcinolone-Acetonide-Neomycin Paste

ZHENG Mu-xiong,LI Jin-xian,XU Min-hong(Guangdong Shantou Skin Hospital,Shantou Guangdong 515041)  
Objective To observe the clinical efficacy and recurrence rate of prurigo nodularis treated with autohemotherapy combined with oral administration of desloratadine as well as triamcinolone-acetonide-neomycin paste.Methods 80 cases were randomized into two groups.In a treatment(40 cases),autohemotherapy was adopted together with oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste.In a control group(40 cases),oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste were applied.The duration of treatment was 30 days in either group.Results 15 cases were cured in treatment group and the effective rate was 82.05%.9 cases were cured in control group and the effective rate was 58.97%.The difference was significant statistically in comparison of the effective rate between two groups(P0.05).The follow-up was conducted for the effective cases 30 days later after treatment.8 cases were recurred in treatment group and the total recurrence rate was 25.00%.13 cases were recurred in control group and the total recurrence rate was 56.52%.The difference was significant statistically in comparison of the total recurrence rate between two groups(P0.05).Conclusion Autohemotherapy combined with desloratadine and triamcinolone-acetonide-neomycin paste reduces the recurrence rate of prurigo nodularis and the clinical efficacy is superior apparently to simple oral administration of desloratadine and topical application of triamcinolone-acetonide-neomycin paste.Thus,this therapy deserves to be promoted in practice.
【Key Words】: Autohemotherapy Desloratadine Triamcinolone-Acetonide-Neomycin Paste Prurigo Nodularis
【CateGory Index】: R758.24
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