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《World Journal of Integrated Traditional and Western Medicine》 2014-04
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Correlative Study on Serum Adiponectin and IL-8 Level with the Condition of Chronic Obstructive Pulmonary Disease in the Patients

HUAI Ping-ai;PENG Bao-hong;Affiliated Hospital of Shanxi University of Traditional Chinese Medicine;  
Objective To observe the correlation of serum adiponectin and IL-8 level with disease severity in the patients of chronic obstructive pulmonary disease( COPD). Methods The levels of serum adiponectin and IL- 8 were determined in 40 cases of stable stage group,42 cases of acute aggravated stage group and 40 cases of healthy control group. The correlation among adiponectin,IL- 8 and PaO2was analyzed among the stable stage group,the acute aggravated stage group and the healthy control group. Results Serum adiponectin level in the stable stage group and the acute aggravated stage group was lower obviously than that in the healthy control group( P 0. 05,P 0. 01). Serum adiponectin level in the acute aggravated stage group was lower than that in the stable stage group( P 0. 05). IL- 8 level in the stable stage group and the acute aggravated stage group was higher than that in the healthy control group( P 0. 05,P 0. 01). IL- 8 level in the acute aggravated stage group was higher than that in the stable stage group( P 0. 05). Serum adiponectin level was correlated positively with PaO2and IL- 8 was correlated negatively with PaO2. Conclusion Adiponectin and IL- 8 are involved possibly in the inflammatory reaction of COPD and the levels of them are correlated with the severity of disease.
【CateGory Index】: R563.9
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