Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Physiologica Sinica》 2014-06
Add to Favorite Get Latest Update

Research progress on autophagy regulating excessive inflammation

XIAO Meng-Jing;LI Li-Gen;Department of Burn and Plastic Surgery, Burn Institute, the First Affiliated Hospital, Chinese PLA General Hospital;  
Autophagy is a highly conserved cellular self-digestion pathway, by which intracellular damaged proteins or organelles are delivered to lysosomes for degradation, so as to protect from various dangerous stimuli and maintain cellular homeostasis. Inflammation is a defensive response to injury or pathogens, through which various inflammatory mediators coordinate host defense and repair. However, uncontrolled inflammatory responses can lead to secondary damage and pathogenesis of inflammatory disease. Recent studies indicate that autophagy pathway and related proteins may play important roles in regulating immune response and controlling excessive inflammation. This review introduced research progress in the role of autophagy in regulating excessive inflammation and possible mechanisms.
【Fund】: supported by the National Natural Science Foundation of China(No.81171808)
【CateGory Index】: R363
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Shu;WANG Bing-yuan;Cadre Department, the First Affiliated Hospital of China Medical University;;Inflammsomes in chronic liver diseases[J];Infectious Disease Information;2013-05
2 Yu-Shan Chen;Xiao-Bo Qiu;Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, and College of Life Sciences, Beijing Normal University;;Ubiquitin at the crossroad of cell death and survival[J];癌症(英文版);2013-12
3 Liu Zhenghui;Han Daishu;Department of Cell Biology,Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences;;Promotion of adaptive immune response by PRR-triggered innate immune signaling[J];Chinese Journal of Histochemistry and Cytochemistry;2013-06
4 Zhang Yuanyuan;Hou Weiping;Cao Xuejiao;Yuan Fahuan;Department of Nephrology,Xinqiao Hospital,Third Military Medical University/Kidney Disease Center of PLA/Kidney Disease Research Institution/Important Special Department,State Administration of Traditional Chinese Medicine;;Expression change of NALP3/ASC/caspase-1 in renal tissues of FSGS[J];Chongqing Medicine;2014-03
5 ;Inflammatory corpuscle in mechanism research progress of fungus infection[J];Chinese Journal of Aesthetic Medicine;2014-11
6 SUN Liang;LIU Wan-lin;Inner Mongolia Medical College;Department of Orthopedics,Second Affiliated Hospital of Inner Mongolia;;Prospective of Autophagy Involved in Molecular Mechanism and Disdases[J];Inner Mongolia Medical Journal;2014-07
7 FAN Liping;LIN Wenlong;WANG Xiaojian;Department of Clinical Laboratory, Second Affiliated Hospital, Zhejiang Chinese Medical University;Institute of Immunology, Medicine School of Zhejiang University;;NLRCs inflammasome subfamilies and their roles in maintaining the balance of normal immune response[J];Immunological Journal;2014-09
8 YANG Jie Ling;XU Hao;SHAO Feng;National Institute of Biological Sciences;National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences;;Immunological function of familial Mediterranean fever disease protein Pyrin[J];中国科学:生命科学(英文版);2014-12
9 LIU Zhong-Yang;LIU Yan;XI Rong-Gang;WANG Xiao-Bo;Institute of Materia Medica of Shenyang Military Region;The 210th Hospital of PLA;;Valosin-Containing Protein/p97,a New Marker of Endocytosis and Autophagy[J];Letters in Biotechnology;2014-03
10 HE Jing;SHI Shaolin;National Clinical Research Center of Kidney Diseases,Jinling Hospital,Nanjing University School of Medicine;;DAMPs and kidney diseases[J];Chinese Journal of Nephrology,Dialysis & Transplantation;2014-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved