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《ACTA PHYSIOLOGICA SINICA》 1995-03
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EFFECTS OF PENTAGASTRIN WITH INTRACEREBROVENTRICULAR INJECTION ON BLOOD PRESSURE AND HEART RATE IN RATS

WANG MING-JIANG; HUANG CHENG-JUN AND ZHANG GONG-SHON (Department of Physiology, Yunyang Medical College, Shiyan 442000)  
Experiments were carried out on 84 artifially ventilated SD rats anaesthetized with urethane and immobilized with gallamine triethiodide. Injection of pentagastrin (G5) into the rat lateral ventricle resulted in a marked elevation in arterial blood pressure which reached its peak at 3 min (from 12. 2±1. 5 to 14.1± 1. 7 kPa) and also a significant increase in heart rate from 435 ± 53. 9 to 471. 6 ± 53. 2 beats/min. This effect of G5 could be partially antagonized by injection of phentolamine (α-receptor antagonist, 10 μg) into the lateral ventricle, but not by propanolol (β-receptor antagonist, 4μg) or atropine (M-receptor antagonist, 4μg). These findings indicate that the central effect of G5 on blood pressure and heart rate is partly mediated by α-receptor.
【CateGory Index】: R331
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【References】
Chinese Journal Full-text Database 1 Hits
1 Wang Ming-jiang1Feng Gui-xiang2He Ting-yun31Department of Physiology2Functional Laboratory3Department of ChemistryYunyang Medical CollegeShiyan 442000Hubei ProvinceChina;Effect of intracerebral ventricular injection of pentagastrin on the pulmonary arterial pressure of rats[J];Chinese Journal of Clinical Rehabilitation;2005-27
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Chinese Journal Full-text Database 10 Hits
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2 Lin Xinwei;Lin Haoran;Zhang Qing Department of Biology, Zhonshang University, Guangzhou 510275 South China Sea Fisheries Research Institute, Guangzhou 510300;GROWTH HORMONE SECRETION AND GROWTH OF CULTURED FISH INDUCED BY GONADOTROPINRELEASING HORMONE ANALOGS[J];Journal of Fisheries of China;1993-04
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4 LIN Shu-gen, WU De-feng, WANG Shou-kun ( College of Animal Science , Fujian Agriculture and Forestry University , Fuzhou 350002, China);Location and identification of endocrine cells in the gastro-entero-pancreas of Anguilla japonicus[J];Journal of Fisheries of China;2003-06
5 PAN Kang-cheng, FANG Jing (College of Animal Science and Technology, Sichuan Agricultural University, Yaan 625014, Sichuan, China);Study on the Telecephlon Morphology and Histology of Schizothorax prenat (Tchang)[J];Journal of Sichuan Agricultural University;2002-02
6 FANG Jing, PAN Kang-cheng, DENG Tian-huai (College of Animal and Technology, Sichuan Agricultural University, Yaan 625014, Sichuan, China);A Scanning Electron Microscopical Observation of the Gill of Schizothorax (Schizothorax) prenanti (Tchang)[J];Journal of Sichuan Agricultural University;2004-02
7 FANG Jing, HE Min (College of Animal and Technology, Sichuan Agricultural University, Yaan 625014, Sichuan, China);Localization and Morphology of G and EC Cells in the Digestive Tract of Schizothorax davidi[J];Journal of Sichuan Agricultural University;2006-01
8 Fang Jing; Zhou Yi(College of animal Science and technology,Experimental center. Sichuan Agricultural Univesity, Yaan, Sichuan China 625014);MORPHOLOGICAL AND HISTOLOGICAL STUDIES ON THE DIGESTIVE TRACTS OF Schizothorax (Schizothorax) PRENAANTI (Tchang) AND Schizothorax(Racoma) DAVIDI (Sauvage)[J];JOURNAL OF SICHUAN AGRICULTURAL UNIVERSITY;1995-01
9 Wu Qing Cai Limin Lu Jianping et al.;STUDIES ON THE TOLERENCE ABILITY OF YOUNG SCLIZOTHORAX PRENANTI TO VARIANCE OF THE WATER TEMPERATURE AND DISSOLVED OXYGEN[J];Journal of Sichuan Institute of Animal Husbandry and Veterinry Medicine;2001-03
10 ZHANG RONG;ZHOU LU;ZHANG BAO-ZHEN Department of Physiology,Institute of Basic Medical Science,Chinese Academy of Medical Sciences,Beijing 100005;THE STIMULATORY EFFECT OF DORSAL VAGAL COMPLEX INJECTION OF PENTAGASTRIN ON GASTRIC MOTILITY IN RATS[J];Acta Physiological Sinica;1993-03
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