Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《ACTA PHYSIOLOGICA SINICA》 1999-03
Add to Favorite Get Latest Update

β ENDORPHIN INVOLVED IN THE REGULATION OF HUMORAL IMMUNE FUNCTION OF RATS DURING ACUTE HYPOXIA 

BAIHAI BO, DUJI ZENG #, ZHENGXIAO XIANG (Department of Biological Science and Medical Engineering, #Department of Biological Science and Technology, Zhejiang University, Hangzhou 310027)  
Abstract In order to investigate the role of β endorphin in the regulation of humoral immune function of rats during acute hypoxia, the effects of β endorphin on mitogen induced spleen lymphocyte DNA synthesis and hemolysin formation as well as IgG production to chicken egg albumen were observed. It was found that after rats received icv injection of β endorphin (1 ng/rat), the T lymphocyte DNA content, the hemolysin forming capacity of SRBC sensitized rats and the IgG level were reduced significantly compared with the control (icv normal saline). Similar suppressive effects on immune function could be found after rats were exposed to 7 km altitude in a hypobaric chamber for 48 h. Pretreatment with icv injection of naltrexone, the immunosuppressive effects of acute hypoxia were partially blocked. Icv administration of β endorphin produced an increase in splenic cathcholamines, similar to those of hypoxia treated group (7 km for 12 h). All the above findings suggest that β endorphin may modulate the immune response to hypoxia stress via opioid receptor and its inhibitory action may be mediated by activating sympathetic nervous system.
【Fund】: 国家自然科学基金 中国博士后科研基金
【CateGory Index】: Q494
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 Wen Yuefei1,Xiao Li2. 1The zhaoqing health school,Guangdong 526021,China;2The Fist People’s hopital of ZhaoQing,Guang dong 52604,China;Effection about the Hyperbaric Oxygenation to the Cellular Immune Function of Hypoxic-ischemi Encephalopathy New Borns[J];International Medicine & Health Guidance News;2005-17
2 XIAO Ju-qing ZHAO Feng-qin YUANG Yan The People's Hospital of Bao'an District,Shenzhen 518101,China;Effect and Mechanism Of Newborns Cellular Immune Function in Asphyxia[J];Journal of Handan Medical College;2006-02
3 ZHU Rong,ZHANG Ying,WANG FangBeijing Sport University,Beijing 100084,China.;The Effect of Modulation of Erythrocyte on Lymphocyte Immune Function and of Lymphocyte Subpopulations at Different Hypoxia Training[J];China Sport Science;2007-03
4 Ma YC, Zhang Y 1Institute of Physical Education, Luoyang Normal University, Luoyang 471022, Henan Province, China; 2Beijing University of Physical Education, Beijing 100084, China;Hypoxia,exercise and immune[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-30
5 Xiao Li,Cai Dingbang,Zhuang Siqi,et al.Department of Pediatrics,The First people's Hospital of Zhaoqing,Guangdong 526021;EFFECT OF β-ENDORPHIN LEVEL ON CELLULAR IMMUNOLOGIC FUNCTION OF ASPHYXIA NEWBORNS[J];Chinese Journal of Coal Industry Medicine;2004-02
6 Xiao Li *,Cai Dingbang,Zhuang Siqi,et al. *Department of Pediatrics,the First People's Hospital of Zhaoqing,Zhaoqing 526021,China;Research on changes and mechanism of immunologic function in newborns with asphyxia[J];Chinese Journal of Practical Pediatrics;2004-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Qiu-Hong LIU Feng-Yun(Qinghai Plateau Medical Research Institute, Xining 810012,China);Adaptation Mechanism of Pika (Ochotona curzoniae) to Hypoxia[J];Chinese Journal of Zoology;2003-05
2 Liu Bai; Feng Weiquan (Exercise Physiology Teaching & Research Section,BUPE,Beijing 1ooo84 Exercise Biochemistry Teaching & Research Section,BUPE,Beijing 1ooo84);Physiological Basis for Altitude Training of Endurance Players[J];Journal of Beijing University of Physical Education;1994-04
3 JIAO Wei (Dept. of Sports Science of Human Body, BUPE, Beijing 100084, China);Effects of Swimming of Different Intensity and in Different Duration on β-endorphin Level in Plasma and Hypothalamus[J];Journal of Beijing University of Physical Education;2002-05
4 REN Bao-lian (Institute of Physical Education, Jimei University, Xiamen 361021, Fujian China);Research on Influence of Large Intensity and Heavy Stress Training on Female Athletes' Immunoglobulins[J];Journal of Beijing University of Physical Education;2004-06
5 ZHANG Ying, ZHOU Fan-yang, TIAN Ye, HU Yang, KONG Zhao-wei,CHEN Xiao-ke (Beijing Sport University, Beijing 100084, China);Effects of Living High-Training Low for 4 Weeks on Blood Leukocyte Counts[J];Journal of Beijing University of Physical Education;2004-09
6 Liu Lan;et al(Qinghai Provincial People's Hospital);OBSERVATION OF IMMUNE FUNCTION OF RBC AT DIFFERENT ELEVATION[J];JOURNAL OF HIGH ALTITUDE MEDICINE;1998-01
7 Cui Jianhua,et al The 18 Hospital of PLA;RESPONSE OF IMMUNE AND METABOLISM OF FAT IN HEALTHY DRIVE-TROOPS AT HIGH ALTITUDE[J];JOURNAL OF HIGH ALTITUDE MEDICINE;2000-02
8 Cui Jianhua,et al The 18 Hospital of PLA;SERUM INTERCELLULAP ADCHESION MOLECULE EXPRESSION OF THE NATIVE AND MIGRATED YOUTHS AT 4 300m ALTITUDE[J];JOURNAL OF HIGH ALTITUDE MEDICINE;2000-03
9 Si Benhui,et al Department of cardiology Qinghai General hospital of Chinese People′s Armed Police forced;EFFECTS OF HYPOXIA ON RBC IMMUNOREACTION[J];JOURNAL OF HIGH ALTITUDE MEDICINE;2000-03
10 Xie Xinmin;et al( Department Of Physiology,Qinghai Medical College);THE EFFECT OF HIGH ALTITUDE STRESS ON β-ENDORPHIN CONTENTS OF RATS BRAIN[J];JOURNAL OF HIGH ALTITUDE MEDICINE;1996-01
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 ZHANG Lu-fen1,YAN Ming-ru1,CHENG Jin-lian2,et al(1 School of Acupuncture and Moxibustion,Beijing University of Chinese Medicine,Beijing 100029;2 Beijing Hospital of Traditional Chinese Medicine);Effect of acupuncture on β-EP levels of plasma,hypothalamus, pituitary and lymph node in rats with adjuvant-induced arthritis[J];Journal of Beijing University of Traditional Chinese Medicine;2007-01
2 LIU Li-ping1,MA Jun1,LI Lei2,BAI Wen-zhong1,CHENG Xi-yue3(1.Department of Human Movement and Science;2.Department of Movement and Training,Hebei Institute of Physical Education,Shijiazhuang 050041,China;3.Third Hospital,Hebei Medical University,Shijiazhuang 050011,China);The effect of flavor preferred learning on the expression of β-endorphin in hypothalamus of rats deprived of sleep and trained for swimming[J];Journal of Physical Education;2008-05
3 LI Yu-zhou1,WANG Rui2,ZHANG Ying3(1.College of Physical Educatiion Henan Normal University,Xinxiang 453000,China;2.Sport Department of Henan Polytechnic University,Jiaozuo 454000,China;3.Sport Science College of Beijing Sport University,Beijing 100084,China);Study on RFER,RFIR and Erythrocyte Immune Function after Different Simulated Hypoxic Trainings in SD Mice[J];Journal of Xi'an Physical Education University;2009-02
4 Liu LX,Qu HL,Wang YQ.1College of Physical Education,Guangxi Normal University,Guilin 541004,Guangxi Zhuang Autonomous Region,China;2College of Physical Education,Yichun University,Yichun 336000,Jiangxi Province,China;Immunocyte,immune molecule and excessive training[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-45
5 ZHANG Hong-shan,SU Hao-bin,MAI You-gang,WEI Jing,WU Yan-yun.Department of Pediatric,Second Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510120,China;The effect of asphyxia on T-lymphocyte subsets in preterm infants[J];Chinese Journal of Neonatology;2009-01
6 ZHENG Ling, LI Xiao-hong, ZHANG Lu-fen, et al. The School of Acupuncture, Beijing University of Traditional Chinese Medicine, Beijing 100029, China;Effect of Dressing and Moxibustion-pretreatment on Local Feet Swelling and Stress Hormone in Hypothalami of Rats with Adjuvant Arthritis at Early and Secondary Stages[J];Chinese Journal of Rehabilitation Theory and Practice;2006-08
7 ZHAN Rui,ZHANG Lu-fen,YAN Jie,ZHANG Hui,SUN Xuan,CHENG Jin-lian,LIU Jian-qiao,YAN Ming-ru,ZHENG Yu;Influence of Acupuncture on Different Issues's β-END Level of Adjuvant Arthritis Model Rats[J];Chinese Journal of Basic Medicine in Traditional Chinese Medicine;2006-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved