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《Chinese Bulletin of Life Sciences》 2009-01
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Progress in the research on neuroprotective effects of puerarin in the central nervous system

LIU Ben-juan,CAO Bao-ping,WU Min-yao(College of Life Science,Shanxi Normal University,Xi'an 710062,China)  
Puerarin is one of the major isoflavonoid compounds isolated from Radix Puerariae,which has been used in traditional Chinese medicine for centuries.The compound was found to inhibit neuronal apoptosis,protect nerve cells against hypoxic/ischemic injuries.Thus,puerarin may be used to treat brain traumas and neurodegenerative diseases.This article reviews the recent progress in research on neuroprotective effects of puerarin and the related mechanisms.
【Fund】: 陕西师范大学留学回国人员科研启动基金(999195)
【CateGory Index】: R285.5
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【Citations】
Chinese Journal Full-text Database 10 Hits
1 YAN Fu-ling*, LU Guo*, WANG Ya-qiong*, HONG Zhen. *Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, ChinaCorresponding author: HONG Zhen, Email: zhong@shmu.edu.cn;Effect of puerarin on the expression of Aβ_(1-40) and Bax in brain of AD rats induced by Aβ_(25-35)[J];Chinese Journal of Neuromedicine;2006-02
2 ZHANG Xiang-tong,SHANG Zhen-de,XIE Chun-cheng,et al.(Department of Neurosurgery,First Affiliated Hospital,Harbin Medical University,Harbin 150001,China);Neuroprotective effect of Puerarin following traumatic brain injury in adult rat[J];Journal of Traumatic Surgery;2007-03
3 JIANG Hong1,WANG Ling2,ZHANG Yi-He1,LIU Shi-Ping1,LIU Guang-Zhong1 1Department of Pediatrics,Affiliated Hospital of Yan'an Univer-sity,Yan'an 716000,China,2Department of Pediatrics,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China;Neuroprotective effects of puerarin in neonatal rats with hypoxic-ischemic brain damage[J];Journal of the Fourth Military Medical University;2008-03
4 LI Guan-Fei,LIU Qun,and QI Zhong-Hua(Department of Neurology,Jilin Provincial People's Hospital,Changchun 130021,China);Study on the Expression of Brain-Derived Neurotrophic Factor and Semaphorin 3A After Focal Cerebral Ischemia in Rats and the Neuroprotective Effects of Puerarin[J];Chinese Journal of Arteriosclerosis;2006-10
5 PAN Deng1,TAN Jun2,ZHAO Xiu-juan3,et al.(1.Department of Gerontology,Xinxiang Municipal First People's Hospital,Xinxiang 453000;2.Department of Neurology,The Third Affiliated Hospital of Xinxiang Medical College,Xinxiang 453002,Henan,P.R.China);Impact of puerarin preconditioning on apoptosis and expression of p53 in focal cerebral ischemia reperfusion injury rats[J];China Tropical Medicine;2007-07
6 Zhang Bingqing,Wang Yuliang(Department of Physiology,Weifang Medical College,Weifang 261042);EFFECTS OF PUERARIN ON HIPPOCAMPAL PYRAMIDAL CELL AND THE EXPRESSION OF BDNF IN VASCULAR DEMENTIA RATS[J];Chinese Journal of Neuroanatomy;2007-06
7 CAO Jian-Zhong, LIU Shu-Shan, YANG Guang-Tian (Dept of Emergency Medicine, Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030);Effects of puerarin on the expression of Bcl-2 and Bax in rat hippcampal CA1 after acute global cerebral ischemia and reperfusion[J];Chinese Pharmacological Bulletin;2003-11
8 CHEN Li-min~(1,2),LU Qiu-jun~1,WEN Li-qing~1,CHEN Yuan-yuan~1,CHEN Zhen-hua~1,XIE Jie-qiong~1,ZHANG Min~1,CAO Ying-lin~2(1.Dept of Pharmacology and Toxicology,Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China;2.Shenyang Pharmaceutical University,Shenyang 110016,China);Protective effects of puerarin on rat primary cultured neurons damaged by glutamic acid[J];Chinese Pharmacological Bulletin;2006-05
9 YANG Dong-Xu, TANG Yu, HU Xiao-Min, LIU Jin-Xue, CHEN Yi, JIN You-Yu Department of Pharmacology, Capital University of Medical sciences, Beijing 100054, China;Effects of puerarin on AD animal model in mice induced by β-amyloid peptide[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2004-06
10 YU Juan,NI Xiu-Shi,XU Yun Department of Neurology, the Affiliated Drum Tower Hospital, Nanjing University, Medical School, Nanjing 210008, Jiangsu, China;Phytoestrogens and progress of protective effects researching on central nerve system[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2004-08
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 XUE Xiao-yang,JI Hong-yan,ZHUO Xiu-zheng, ZHANG Nian-zhi,DAI Xiao-hua,ZHOU Yi-xuan (The First Affiliated Hospital,Anhui College of TCM,Anhui Hefei 230031,China);32 CASES OF ANGINA PECTORIS TREATED WITH PUERARIN INJECTION[J];Journal of Anhui Traditional Chinese Medical College;2001-03
2 ZHENG Hao(College of Life Science,Northwest A & F University,Yangling 712100,China);Advances of Research And Development of Pueraria Radices[J];Amino Acids & Biotic Resources;2006-02
3 YAN Fu-ling*, LU Guo*, WANG Ya-qiong*, HONG Zhen. *Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, ChinaCorresponding author: HONG Zhen, Email: zhong@shmu.edu.cn;Effect of puerarin on the expression of Aβ_(1-40) and Bax in brain of AD rats induced by Aβ_(25-35)[J];Chinese Journal of Neuromedicine;2006-02
4 ZHANG Xiang-tong,SHANG Zhen-de,XIE Chun-cheng,et al.(Department of Neurosurgery,First Affiliated Hospital,Harbin Medical University,Harbin 150001,China);Neuroprotective effect of Puerarin following traumatic brain injury in adult rat[J];Journal of Traumatic Surgery;2007-03
5 WU Hai-qin, WANG Hu-qing, CHENG Hong-xue, ZHANG Gui-lian, ZHAN Shu-qin Department of Neurology, Second Hospital Affiliated to Xi'an Jiaotong University College of Medicine, Xi'an 710004, China;Expression of hypoxia inducible factor-1α in different brain regions in aged rats[J];Journal of Southern Medical University;2008-10
6 LIU Ke - yun, HUANG Xian - zhen (Medical Collage, Hubei Institute for Nationalities, Enshi 445000, China);Protective Effect of Puerarin on Qinolinic Acid Induced Cytotoxicity on Cultured Hippocampal Neurons of New - borne Rats[J];Journal of Hubei Institute For Nationalities Medical Edition;2005-04
7 ZHENG Wei Xing,GAI Xiao bo,LUO Zhu rong,et al (Fuzhou General Hospital of Nanjing Military Area,Fuzhou,Fujian 350025,China) \;;Protective Effects of Puerarin on Endothelial Dysfunction in Patients with Acute Coronary Syndrome[J];Journal of Fujian College of Traditional Chinese Medicine;2002-04
8 ;葛根的药理作用研究概况[J];Guangming Journal of Chinese Medicine;2006-03
9 Huang Zhu-yan~1, Zhao Yan-tao~2,Li Yan~1(1 Chemical Engineering Institute of Guizhou University,Guiyang Guizhou 550003,China;2 College of Animal Science and Technology, Northwest A & F University, Yangling Shanxi 712100,China);Progress of Pueraria lobata in Pharmacological effect and Clinical application[J];Guangming Journal of Chinese Medicine;2007-06
10 Gao Jing 1,Kan Fangxu 2,Liu Qian 1 ,Liu Guifang 1 (1. Shandong University of TCM , 250014 , Ji'nan ,China ; 2. Zibo Hospital of TCM , 255300 ,Zibo ,China);Puerarin for the acute coronary syndrome of non-ST elevation: an observation of curative effect[J];Journal of Gansu College of Traditional Chinese Medicine;2005-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Hu Lan,Zou Jizhen (Capital Institute of Pediatrics,Beijing 100020);TUNEL and BCL-2 expresion of newborn-rat HIBD by puerarin[J];Beijing Medical Journal;2004-02
2 Li Xi( Second Affliated Hospital of Xi' an medical University, Xi' an );Effect of Nao Er Kang on Learning and Memory Disorders in Model Rats with Alzheimer's Diseases[J];China Journal of Traditional Chinese Medicine and Pharmacy;2001-05
3 YAN Fu-ling*, LU Guo*, WANG Ya-qiong*, HONG Zhen. *Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, ChinaCorresponding author: HONG Zhen, Email: zhong@shmu.edu.cn;Effect of puerarin on the expression of Aβ_(1-40) and Bax in brain of AD rats induced by Aβ_(25-35)[J];Chinese Journal of Neuromedicine;2006-02
4 LI Nian-jin.Department of Neurosurgery,People's Hospital of Yuncheng County,Yuncheng 274700,China;Clinical research advance in neurotrophins[J];Chinese Journal of Neuromedicine;2006-07
5 SANG Han Fei 1, ZHANG Ying Min 1, XU Li Xian 2, WANG Qiang 1, JI Gen Lin 1, WU Ming Chun 1 1Department of Anesthesiology, Xijing Hospital, 2Department of Anesthesiology, Stomatological College, Fourth Military Medical University, X;Protective effect of puerarin on spinal cord injury resulting from ischemia and reperfusion in rabbits[J];Journal of The Fourth Military Medical University;2001-05
6 MALi1,SUNZhi1,MAHui-qing2(1.Jining Medical college,ShandongJining 272013,China;2.Maternal and Children Health CareHospital ofShanxian,Shandong Shanxian 274300,China);Application of the Chinese Medicinal Herbs in the treatment of neonatal hypoxic-ischemic encephalopathy[J];Journal of Pediatric Pharmacy;2006-03
7 YAN Zheng, LIU Fan, LIN Dun\|bin, KANG Qiang, HE Yu\|mei, LIN Dong\|ru Department of Pediatrics, Fuzhou First Hospital, Fuzhou\ 350009, China;Changes of Plasma Endothelin and Nitric-oxide in Neonates with Hypoxic-ischemic Encephalopathy[J];Journal of Fujian Medical University;2003-04
8 SHI Wei-dong, WANG Kong-bao, QIN Qi-sheng (People's Court of Qingdao, Qingdao 266071; Department of Forensic Pathology,Tongji Medical College of Huazhong University of Science and technology,Wuhan,430030);Trauma brain injury and apoptosis[J];Journal of Forensic Medicine;2003-01
9 GAO Peng,XIA Chengqing,WANG Peiyan,et al.Beijing Red Cross Chaoyang Hospital Affiliate of Capital University of Medical Science,Beijing 100020,China;Observation of the puerarin's effect on cerebral inducible nitric oxide synthase during global cerebral ischemia and reperfusion[J];Journal of Emergenoy Medicine;2001-02
10 XU Xiao-wu, XU Jie (Department of Anatomy, Zhongshan Medical College, Sun Yat-sen University, Guangdong Guangzhou 510080 China);Advance of the Effect of Phytoestrogen on Alzheimer's Disease[J];Progress of Anatomical Sciences;2004-02
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