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《CHINESE JOURNAL OF INDUSTRIAL MEDICINE》 1999-03
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Studiesontheprotectiveeffectsofdifferentabsorbentsagainstperfluoroisobutylene

ZhangXiancheng,WangWenzhu,PengShuangqing,etal.DepartmentofMilitaryToxicologyofInstituteofPharmacologyandToxicology,AcademyofMilitaryMedicalSciences.Beijing100850  
Objective Inordertoeffectivelyprotecttheacutelunginjurybyinhalationofperfluoroisobutylene(PFIB),themajortoxicelementinthepolymerfumeproducedbythermaldecompositionofpolytetrafluoroethyleneinplasticindustry. Methods AnPFIBexposuresystemforlaboratoryanimalswasdesigned,andtheprotectiveeffectsofdifferentabsorbentsagainstPFIBwerestudied. Results TheresultsshowedthattheinorganicabsorbentsshowednoanyeffectonabsorbingPFIB,theactivatedcarbonshadgoodabsorbingeffectbutquitedifferredeachotherinthisaspect,Guanghuaactivatedcarbonwasthebestamongthem.IncreasedhumiditywillobviouslydecreasetheircapabilityofabsorbingPFIB,ahumidityover65%willmakethemtotallylosetheabsorbingcapability.SeriousdamagesinthelungssuchaspulmonaryedemawerefoundinmicewheninhaledthetailgasproducedbyPFIBpenetratingthroughGuanghuaactivatedcarbon.WhichwasverifiedasamixtureofPFIBanditsdecomposedproductssuchashexafluoroisobutyricacidandhydrogenfluoride.Conclusion ItissuggestedthatactivatedcarbonsespeciallyGuanghuaactivatedcarbonmayoffordaneffectiveandsa
【CateGory Index】: R136.3
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【Co-references】
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1 MENG Ge,WANG He-mei,ZHAO Jian,DING Ri-gao,ZHANG Xian-cheng,HUANG Chun-Qian (Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850,China);Long-term effect of a single perfluoroisobutylene exposure induced acute lung injury in mice[J];中国药理学与毒理学杂志;2011-06
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【Secondary References】
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