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《CHINESE JOURNAL OF INDUSTRIAL MEDICINE》 1999-03
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StudiesonEffectsofExposuretoFluorideonBloodAntiOxidaseandPreventiveEffectsofKangfuxin

QiCheng,ChenRongan,YuDalin,etal. DepartmentofOccupationalHealth,SchoolofPublicHealth,TongjiMedicalUniversityWuhan430030BZ  
Objective TostudyeffectsofexposuretofluorideonbloodantioxidaseandinterventioneffectsofKangfuxin. Methods SixtyeightworkersexposedtofluoridewereselectedanddividedrandomlyintogroupsAandB.GroupAwasadministeredwithKangfuxinorallyandgroupBwithoutdrugascontrol.Inaddition,29unexposedworkerswereselectedascontrolgroupC.Allthethreegroupswerefollowedupfortwomonthsonthespots. Results Exposuretofluoridecouldincreasetheburdenoffluorideintheirbodies,decreaseactivityofsuperoxidedismutase(SOD)intheirredbloodcellsandincreaseplasmalevelofMDA.TheirexcretionoffluorideandactivityofantioxidaseincreasedandplasmalevelofMDAreducedinthegroupAaftertakingthedrug. Conclusion Kangfuxinhadcertaineffectsofpreventionfromthedamagecausedbyfluoride.
【CateGory Index】: R135.14
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