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《Medical Journal of Qilu》 2001-01
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ZHANG Shunkai,PAN Guangqiang, YI Xingyang, et al Department of Neurology, Ruian People's Hospital, Ruian 325200, Zhejiang  
Objective To study the clinical therapeutic effect and safety of different-dosage naloxone in acute cerebral infarction(ACI). Methods 120 cases of ACI were randomly divided into two groups: naloxone-treating group and the control group(given venoratone). The naloxone-treating group was then randomly subdivided into high-dosage group and low-dosage group. According to the defect grade of nervous function, we judged the curative effect on the different therapies. Results The effective rate in the high-dosage naloxone-treating group was significantly superior to that in the control group(μ= 2.163, P0. 05). There was no apparent side effects during the treatment. There was no marked difference between the low-dosage naloxonetreating group and the control group(μ= 0.726, P0.05). The therapeutic effect of the high-dosage naloxone given within 48 hours was significantly superior to that after 48 hours (t=2.473, P0.05 ). Conclusion High-dosage of naloxone is effective and safe in the treatment of ACI. The use of naloxone is better in the early stage.
【CateGory Index】: R743.33
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Chinese Journal Full-text Database 2 Hits
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Chinese Journal Full-text Database 1 Hits
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