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《Food Science》 2006-08
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Study on Anti-tumor Effects of Flavonoids Extracted from Sweet Potato Leaf,Stalk and Stem

LUO Li-ping,GAO Yin-yu*,HONG Xue-e,XIA Dong-hua,CHEN Cai-shui(Key Laboratory of Food Science,Ministry of Education,Nanchang University,Nanchang 330047,China)  
The antitumor effects of FSPV were studied in this paper.By using MTT assay and dye exclusion method,the inhibitory effects on 4 tumor cell lines in vitro of FSPV were studied.Cyclophosphamide was the positive control and saline the negative control.S180-bearing mice were used as animal model.The changes of tumor weight in vitro were investigated when FSPV were used.Results:The growth of 4 tumor cells is inhibited by FSPV significantly in dose-dependent manner.Especially the inhibitory effect on the HL-60 is specific up to 70.95%.The antitumor effect of FSPV on the S180 bearing mice is significant.The inhibitory rate is highest when the dose is 400mg/kg bw.Conclusion:FSPV have the antitumor effects on the 4 tumor cell lines and S180-bearing mice.
【CateGory Index】: R285.5
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