Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Food Science》 2008-09
Add to Favorite Get Latest Update

Antitumor Activity of Extracellular Polysaccharides from Morchella esculenta

CHEN Yan1,2,PAN Jian1,ZHOU Li-wei3,ZHANG Li-ping2,YANG Yi1 (1.Engineering Research Center of Bio-process,Ministry of Education,Hefei University of Technology,Hefei 230009,China; 2.School of Life Science,Anhui University,Key Laboratory of Chinese Traditional Medicine Research and Development of Anhui Province,Hefei 230039,China;3.College of Tea and Food Science Technology,Anhui Agricultural University,He fei 230036,China)  
Objective: To study the antitumor effects of extracellular polysaccharides from Morchella esculenta (EPM) and the immunological function on S180 tumor-bearing mice. Method: EPM was intragastrically given to S180-bearing mice at the dose of 200 mg/kg and 400 mg/kg. Normal sodium and cyclophosphamide were taken as blank control and positive control respectively. The tumor weight, immunologic organ weights and life span of S180-bearing mice were measured. S180 tumor cells were incubated with various concentrations of EPM for 24 h, and antiproliferative activities against tumor cells were determined by MTT assay. Result: EPM significantly increases the spleen index, percent of T-lymphocyte, macrophage phagocytic index and prolongs survival time of S180-bearing mice.The inhibiting tumor rates at the low and high does are 49.04% and 64.42% respectively. EPM can kill S180 tumor cells directly in vitro, with the highest inhibiting rate 46.3% at the dose of 50μg/well.Conclusion: EPM has significant antitumor effects and improves immunological function.
【Fund】: 教育部科技创新工程重大项目培育基金(7074027);; 安徽省自然科学基金项目(070413143)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 8 Hits
1 Zhang Liping; Miao Chunyan; Zhang Bingxen (Department of Biology, Northeast Normal University, Changchun, 130024);Study on Structural Determination and Anti-tumor Activity of Fomes Pinicola Polysacchrides FP_2[J];JOURNAL OF NORTHEAST NORMAL UNIVERSITY (NATURAL SCIENCE EDITION);1994-02
2 Sun Yujun~1 Chen Yan~2 Zhou Liwei~2 1(School of Life Science,Anhui Science and Technology University,Fengyang 233100,China) 2(School of Life Science,Anhui University,Hefei 230039,China);Isolation,Purification and Characterization Analysis on Intracellular Polysaccharide MEP-Ⅱfrom Morchella esculenta[J];Food and Fermentation Industries;2007-12
3 Jia janhui et al.;Studies on Extraction,Separation and Purification of the Submerged-fermentation Morchella Polysacharide[J];Food Science;2002-04
4 Wei Yun Zhang Tianyou Zhang Shu Liu Qinghui (Beijing Institute of New Technology and Application, Beijing 100035);Isolation, Purification and Property Identification of MEP-SP1[J];Acta Edulis Fungi;1999-03
5 LI Juan, WANG Zhen, YAO Liang-tong, JIA Le(Coll. of Life Sci. Shandong Agric. Univ. Tai'an 271018);Advanced in Morchella esculenta Polysaccharides Studies[J];Journal of Microbiology;2005-04
6 Jiang Zibin(Jiang ZB),Li Hua(Li H),Cao Jichao(Cao JC)(Department of Biochemical Pharmoceutics,Shandong Medical University,Jinan 250022);Studies on the properties and antitumor activity in vitro of the glycoprotein from pleurotus ostreatus[J];CHINESE JOURNAL OF MODERN APPLIED PHARMACY;2000-02
7 QI Chun Hui, ZHANG Yong Xiang, LI Feng Xian, QIAO Shan Yi, YAO Xin Sheng 1, Haruki Yamada 2 (Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850);Preliminary study on anti tumor action of polysaccharides isolated from Liuwei Dihuang Decoction in vitro[J];CHINESE PHARMACOLOGICAL BULLETIN;1999-04
8 WEI Yun, ZHANG Tian\|you, ZHANG Shu, LIU Qing\|hui (Beijing Institute of New Technology and Application, Beijing 100035);Isolation, purification and characterization of polysaccharides from Morchella essulenta L.[J];JOURNAL OF PLANT RESOURCES AND ENVIRONMENT;2000-02
Chinese Journal Full-text Database 10 Hits
1 LUO Ao-xue et al(Dujiangyan Campus of Sichuan Agricultural University,Dujiangyan,Sichuan 611830);Study on the Protein Removal of the Crude Polysaccharide from Dendrobium[J];Journal of Anhui Agricultural Sciences;2008-29
2 CHEN Jian-jun et al(Research Center of Hydrobiology,Jinan University,Guangzhou,Guangdong 510632);Review on the Ecological Niche and Culture Techniques of Morchella[J];Journal of Anhui Agricultural Sciences;2009-02
3 Xiong Zhengying Zhang Haixin (Institute of Exercise Biology,Shanxi Normal University,Xi'an 710062);Relationship between Morchella Esculenta and Exercise Performance[J];Journal of Anhui Sports Science;2004-03
4 WU Qian- Qian1,2,LI Chun- Ru1,FAN Mei- Zhen1(1. Anhui Provincial Key Laboratory for Microbial Control, Anhui Agricultural University,Hefei,230036; 2. Department of Biological & Environmental Engineering,Hefei Univesity,230022,China);Study on Extraction Conditions of Polysaccharide from aStrain of Acremonium Terricola[J];Packaging and Food Machinery;2005-01
5 LI Zheng-peng1,2,CAI Yong-ping1,LIN Yi1,LI Ting-chun1,FAN Hong-hong1(1.Anhui Agricultural University,Hefei 230036,Anhui China; 2.Anhui Science and Technology University,Fengyang 233100 China);The Extraction of Polysaccharide from Submerged Fermentation of Pleurotus ferulae[J];Packaging and Food Machinery;2005-06
6 Yun Jianmin (Department of Food Engineering,GansuAgriculturalUniversity,LanZhou 730070);A Study on Processing Morel Nutritional Liquid[J];Journal of Gansu Agricultural University;1997-01
8 LI Qiao-yun,ZHAI Chun,JU Hong-fang,GE Fen-feng (Department of Chemistry, Changshu College, Jiangsu Changshu 215500, China);Study on the Extraction Technology of Polysaccharide from Arimillaria Mellea[J];Huaxue Shijie (Chemical World);2004-07
9 LIN Min1 WU Dong-qing2 LI Cai-xia3(1,2.Chamical Department,Hexi University,Zhangye Gansu,China 734000 3.Biological Department,Hexi University,Zhangye Gansu,China 734000);TECHNOLOGY STUDY ON EXTYACTION OF POLYSACCHARIDE FROM AURICULARIA[J];Journal of Hexi University;2004-05
10 CHEN Mei-zhen,YU-Jie,LIAO Zao-hui,WANG-Xin(Department of Biology,Shantou University,Shantou 515063,China);Study on the antitumor activity and antioxidation of polysaccharide from Gracilaria lemaneiformis in sarcoma180 bearing mice[J];Chinese Journal of Marine Drugs;2008-02
China Proceedings of conference Full-text Database 1 Hits
1 Zhao Qi1,2,Huan Yunting1,Xu Zhongzhi2,Li Rongchun1 (1.Edible Fungi Institute,Yunnan Agricultural University,Kunming 650201; 2.Institute of Alpine Economic Plants,Yunnan Academy of Agricultural Sciences.Lijiang 674100);An Analysis on the Present Situation of the Cultivation of Morels[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LI Feng-xian FENG Xing-wan CHENG Jun-ping WEI wen(Inst pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850 );ESTABLISHMENT OF NITROGEN MASTARD-RESISTANT HUMAN LEUKEMIA HL60 SUBLINE AND ITS CHARACTERIZAIT0N[J];CHINESE JOURNAL OF CANCER;1994-03
2 CHEN Yan~1, SHEN Ye-shou~1, ZHAO Zhi-ping~1,HU Li-de~2, ZHONG Zai-xin~1 (1.School of Life Science, Anhui University ,Hefei 230039, Anhui,China; 2.School of Life Science, Fudan University , Shanghai 200433, China);Purification and Physico-chemical Properties of Polysaccharides PSM2b from Moutan Cortex of Paeonia suffruticoas Andr[J];Acta Laser Biology Sinica;2004-03
3 Wu Boliang Wang Xuan Yang Won Huang Ranyang Wan Jiangxin (Dept.of Biology) Luo Yuxiang Liu Jicshen (Center for Reproductive Immunology Research);Preliminary Studies on Physical and Chemical Properties of Trichoanthes Cucumeroides Maxim(Wanggua)Glycoproteins and its Killing Effect on Lung Cancer[J];Journal of Jinan University;1990-01
5 LIU Mei Qin * , LI Jian Zhong and KONG Fan Zuo ( Research Center for Eco environmental Sciences, the Chinese Academy of Sciences, Beijing 100085, China );Purification, Characterization and Immunological Function of a New Polysaccharide protein Complex (LE) from Cultured Mycelia of Lentinus edodes[J];ACTA BIOCHIMICA ET BIOPHYSICA SINICA;1999-01
6 Lin Yuye(Microbiology Engineering Institute,Fujian Normal University, Fuzhou,350007) Yang Hong(Light Industry Department, Fuzhou University, Fuzhou,350002);Extraction of Tremella fuciformis Polysaccharides by Enzymatic Technique[J];FOOD AND FERMENTATION INDUSTRIES;1995-01
7 Wu Ke Yu Zhou (Hefei Union University,Biotech. Institute,Hefei,230022);Studies on Optimal Technical Conditions of Polysaccharides Isolation from Flammulina Velutipes[J];FOOD AND FERMENTATION INDUSTRIES;1998-04
8 Jia janhui et al.;Studies on Extraction,Separation and Purification of the Submerged-fermentation Morchella Polysacharide[J];Food Science;2002-04
9 Wei Yun Zhang Tianyou Zhang Shu Liu Qinghui (Beijing Institute of New Technology and Application, Beijing 100035);Isolation, Purification and Property Identification of MEP-SP1[J];Acta Edulis Fungi;1999-03
10 Kong Qingsheng(Kong QS),Jiang Ying(Jiang Y)(Department of Biochemicstry,Jining Medical College,Jining′s 272013);Isolation purification of polysaccharide from the pumpkin and the study of its monosaccharide composition[J];CHINESE JOURNAL OF MODERN APPLIED PHARMACY;2000-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved