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《Food Science》 2009-15
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Sleep-promoting Effect of L-Theanine on Mice

LI Liang1,2,LIN Zhi1,HE Pu-ming3,HAN Quan3,RUAN Zheng3,L Hai-peng1,TAN Jun-feng1,GUO Li1 (1. Key Laboratory of Tea Chemical Engineering,Ministry of Agriculture,Tea Research Institute,Chinese Academy of Agricultural Sciences,Hangzhou 310008,China;2. Graduate School of Chinese Academy of Agricultural Sciences,Beijing 100081,China; 3. Department of Tea Science,Zhejiang University,Hangzhou 310029,China)  
The effects of L-theanine on barbiturate-induced sleeping time,subthreshold barbiturate-induced sleeping time and barbiturate-induced sleeping latency period in mice were investigate. Healthy ICR mice were randomly divided into four groups of 12 mice each:control group fed with distilled water and three treatment groups fed L-theanine at low-,medium-,and high-doses of 50,100 and 200 mg/(kg bw·d). for 30 days. L-Theanine was able to improve sleep function of mice to a certain extent and the best effect was found in the medium-dose-treated mice. However,no direct hypnotic effect of L-theanine was observed while it was able to prolong the sleeping time induced by pentobarbital sodium [that of the medium-dose-treated mice reached (40.3 ± 26.0) min] and to enhance the sleeping rate induced by barbital sodium at the threshold dose (that of the medium-dose-treated mice reached 33.3%). L-Theanine also could significantly decrease (P 0.05) the sleeping latency period induced by barbital sodium [that of the medium-dose-treated mice reached (30.32 ± 4.8) min].
【Fund】: “十一五”国家科技支撑计划项目(2006BAD06B01)
【CateGory Index】: R285
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【Citations】
Chinese Journal Full-text Database 6 Hits
1 LU Yi1, GUO Wen-fei2, NI Jie-er3, YANG Xian-qiang1 (1. Department of Tea Science, Zhejiang University, Hangzhou 310029, China; 2. Department of Chemistry, Zhejiang University, Hangzhou 310027, China; 3. Ningbo Medicine College, Ningbo 315104, China);The Bioactivities and Synthesis of Theanine[J];Journal of Tea Science;2003-01
2 NING Jing~(1,2) LI Jian-quan~1 ZHONG Xing-gang~1 1 Hunan Tea Research Institute,Changsha 410125,China; 2 Tea Science Department of Horticulture and Landscape College,Hunan Agricultual University,Changsha 410128,China;Physiological Functions,Preparation Methods and Application of Theanine[J];Tea Communication;2006-04
3 PENG Qing Tao,HU Wen Xiang,CHEN Pei Rang,WANG Jian She (Institute of Military Medicine,Headquarters of General Equipment,Beijing 100101 China);Effect of Mian Erkang Capsules on the Sleep Improvement of Mice[J];Pharmaceutical Journal of Chinese People's Liberation Army;2003-02
4 Ling Guanting (Shanghai Food Ind. Res. Inst. Shanghai 200052);Exploitable Food Additives (Ⅷ): L-Theanine and its functional activity[J];Journal of Cereals & Oils;2003-05
5 LIN Xue-ling1,CHENG Zhao-hui2,HUANG Cai-huan1,LI Yan1*(1.The Food Sci-Tech Dept., Jinan University, Guangzhou 510632, China;2.The Pharmacy Dept., Jinan University, Guangzhou 510632, China);Study on the Effect of Theanine on Mice's Learning and Memorial Capabilities[J];Food Science;2004-05
6 WANG Xiao xue,QIU Jun,SONG Yu,et al.Public Helath School,Harbin Medical University(Harbin 150001,China);Study on Effect of Theanine of Fatigue[J];China Public Health;2002-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Wang Huihuang(Huangshan in Anhui Province Tea secondary schools,Tunxi,245031);Discussion on Chemical Color Tea by Drinking Olympic Rings Tea[J];Anhui Agricultural Science Bulletin;2008-16
2 CHENG Liu et al (College of Forestry and Horticulture,Sichuan Agricultural Universality,Yaan,Sichuan 625014);An Overview of Progress in Vitro Culture of in Tea Plants and its Influencing Factors[J];Journal of Anhui Agricultural Sciences;2007-07
3 SI Xiong-yuan et al(Bitechology Center of Anhui Agricultural University,Hefei,Anhui 230036);Simultaneous Determination of Water-soluble Vitamins in Tea by Capillary Electrophoresis[J];Journal of Anhui Agricultural Sciences;2008-03
4 GAO Qing-qing et al(Key Laboratory of Tea Chemical Engineering,the Ministry of Agriculture,Tea Research Institute,China Academy of Agricultural Science,Hangzhou,Zhejiang 310008);Isolation and Bioactivity Analysis of Ethyl Acetate Extract of Dajiling Black Tea[J];Journal of Anhui Agricultural Sciences;2008-16
5 ZHANG Jun-gang et al (Hebei Control Center for Disease Prevention and Control,Shijiazhuang,Hebei 050021);Study on the Anti-fatigue Function of Hypsizygus marmoreus Function Food[J];Journal of Anhui Agricultural Sciences;2008-19
6 HUANG Zhen-xing et al (Key Laboratory of Industrial Biotechnology,Ministry of Education,Jiangnan University,Wuxi,Jiangsu 214122);Effects of Microorganisms on the Quality of Puer Tea during Piling and Its Research Progress[J];Journal of Anhui Agricultural Sciences;2008-28
7 WANG Guang-ming et al (Xinyang Agricultural College,Xinyang,Henan 464000);Influences of Infusing Time on Chemical Component in the Tea Infusion of Xinyangmaojian[J];Journal of Anhui Agricultural Sciences;2008-31
8 CUI Hong-chun et al (Agricultural Ministry Key Laboratory of Chemistry and Engineering of Tea,Tea Research Institute of China Agricultural Science Academy,Hangzhou,Zhejiang 310008);Development on the Study of the Chemical Structure of Tea Polysaccharides[J];Journal of Anhui Agricultural Sciences;2009-01
9 ZHOU Zeng-zhi et al(School of Pu-er Tea,Yunnan Agricultural University,Kunming,Yunnan 650201);Study on Extraction Technology of Tea Polysaccharide of Pu-er Tea[J];Journal of Anhui Agricultural Sciences;2009-11
10 CUI Hong-chun et al(Tea Research Institute,CAAS,Key Laboratory of Tea and Drinkable Crops Processing and Quality Control of Agriculture Ministry,Hangzhou,Zhejiang 310008);Study on the Interferences of Chemical Components on the Mensuration of Tea Polysaccharides[J];Journal of Anhui Agricultural Sciences;2009-18
China Proceedings of conference Full-text Database 10 Hits
1 Wang Xin-chao, Chen Liang, Ma Chun-lei, Zhang Ya-li, Mei Ju-fen, Zhao Li-ping, Yao Ming-zhe (Key Lab of Tea Chemical Engineering, Ministry of Agriculture,Tea Research Institute Chinese Academy of Agricultural Sciences, Hangzhou 310008, China);A Preliminary Screening of High β-carotene Content Tea Germplasms[A];[C];2006
2 Li Daxiang, Song li (Key Laboratory of Tea Biochemistry & Biotechnology of Ministry of Agriculture and Education of China, Anhui Agricultural University, Hefei230036);Comparison of Ferrous Tartrate Method with Folin-Ciocalteu Method on tea polyphenols quantitation[A];[C];2006
3 Li Lixiang, Wang Renyue, Dong Ruixia, Huang Nanshan Key Laboratory of Tea Biochemistry & Biotechnology, Ministry of Agricultural, Anhui Agriculture University, Hefei, 230036, China; Department of Tea Science, Anhui Agriculture University, Hefei, 230036, China;Analysis of color of black tea liquor[A];[C];2006
4 Liu Yuan, Wang Jian (Food Science Department, Hebei North university , Zhangjiakou,075000);The Advanced Progresses in Studies of Theanine[A];[C];2007
5 LU Wen-yuan, CHENG Hao*, WANG Li-yuan, ZHOU Jian (Key Lab of Tea Chemical Engineering, Ministry of Agriculture; Tea Research Institute, Chinese Acade my of Agricultural Sciences, Hangzhou 310008, China);Response surface methodology for optimization of fermentation condition of the genetically engineered Escherichia coli strain for the biosynthesis of theanine[A];[C];2007
6 WANG Li-yuan, CHENG Hao, ZHOU Jian (Key Lab of Tea Chemical Engineering, Ministry of Agriculture; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China);A Comparison of the Catalytic Ability of Various Polyphenol Oxidases(PPOs) from plants on Theaflavin Biosynthesis and Molecular cloning and sequence analysis of PPO mature peptide from Camellia sinensis[A];[C];2007
7 Zhang Jian-yong1, 2, Jiang He-yuan*1, Jiang Yong-wen1 (1.Key Laboratory of Tea Chemical Engineering, the Ministry of Agriculture, Tea Research Institute, Chinese Academy of Agriculture Sciences, Hangzhou 310008,China; 2. Chinese Academy of Agriculture Sciences, Beijing 100081,China);Study on the Impact of Caffeine and BSA on the Formation of TFDG by the Chemical Oxidation of EGCG and ECG[A];[C];2007
8 LI QI, HUA-YAN ZHANG, ZHENG-ZHU ZHANG※,XIAO-CHUN WAN (Key Laboratory of Tea Biochemistry & Biotechnology, Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, Hefei 230036 China.);Antifungal Chemical componoents and Their Effect in Tea Leaves[A];[C];2007
9 WANG Hua, LI Daxiang, WAN Xiaochun, Wei Zhiwen (Key Laboratory of Tea Biochemistry &Biotechnology of Ministry of Agriculture and Education, Anhui Agricultural University, Hefei230036);Studies on the DPPH radical scavenging activity of thearubigins[A];[C];2007
10 ZHU Wen-xian1、2,WANG Li-yuan1 ,CHENG Hao1,LI Xing-hui2 (1.Tea Research Institute,Chinese Acade my of Agricultural Sciences ,Zhejiang,Hangzhou 310008,China; 2.Nanjing Agricultural university,Jiangsu,Nanjing 210095,China);The Construction and Expression of E.coli Recombinant For Theanine Production[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Chen ying * Zhong Junhui Tao Wenyi ( *Shaoxing College of Art and Science Shaoxing 312000) (Wuxi university of Light Industry Wuxi 214036);Purification of Theamine with Cation Resin Chromatography[J];AMINO ACIDS & BIOTIC RESOURCES;1998-01
2 LU Yi1, GUO Wen-fei2, NI Jie-er3, YANG Xian-qiang1 (1. Department of Tea Science, Zhejiang University, Hangzhou 310029, China; 2. Department of Chemistry, Zhejiang University, Hangzhou 310027, China; 3. Ningbo Medicine College, Ningbo 315104, China);The Bioactivities and Synthesis of Theanine[J];Journal of Tea Science;2003-01
3 ZHANG Ying, SHI Zhao-peng (Hunan Agricultural University, Changsha 410128, China);Theanine Preparation with Preparative HPLC[J];Journal of Tea Science;2004-04
4 XIAO Li-zheng1,XIAO Wen-jun1,2,GONG Zhi-hua1,WANG Wei2,LIU Zhong-hua1,2*(1.College of Food Science and Technology,Chang sha 410128,China;2.Natural Products Institute of Hunan Agricultural University,Changsha 410128,China);Study on Separation and Concentration of Theanine in De-catechined Tea Extracts by Membrane System[J];Journal of Tea Science;2006-01
5 Yuan Haibo,Tong Huarong,Gao Aihong (Food Science institute of Southwest Agriculural University Beibei Chongqing);The synthetic method and properties of Theanine[J];Guangzhou Food Science and Technology;2002-02
6 GAO Xiao-hong, YUAN Hua, YU Zong-yuan (Hubei Research Institute of Chemistry, Wuhan 430074,China);Research Progress of L-Theanine[J];;2004-01
7 WANG San yong,LI Xiao guang,LI Chun rong,LI Shao xiong (Guandong Food Industry Institute,Guangzhou 510315,China);Synthesis of L-Theanine[J];Fine Chemicals;2001-04
8 Ling Guanting (Shanghai Food Ind. Res. Inst. Shanghai 200052);Exploitable Food Additives (Ⅷ): L-Theanine and its functional activity[J];Journal of Cereals & Oils;2003-05
9 ZHU Song, WANG Hong-xin (School of Food Science and Technology, Southern Yangtze University, Jiangsu Wuxi 214036, China);Physiological Functions and Application of Theanine[J];Journal of Cereals & Oils;2005-01
10 Zhao Dan et al.;Review on Research Status of Theanine[J];Food Science;2002-05
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