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《Food Science》 2012-01
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Hypolipidemic and Liver-Benefiting Effect of Sweet Potato Resistant Starch in Hyperlipidemic Rats

YU Miao,WU Ying-long (College of Food Science,Sichuan Agricultural University,Ya'an 625014,China)  
Objective: To examine whether sweet potato resistant starch(SPRS) lowers blood lipid levels and benefits the liver of hyperlipidemic rats.Methods: Forty SD rats(half male and half female) were randomly divided into 4 groups including normal control group,hyperlipidemia model group,SPRS low-dose group and SPRS high-dose group.Rats fed a normal diet were served as the normal control group and rats fed a high-fat diet as the hyperlipidemia model group.The rats in SPRS groups were administered with SPRS by gavage at the daily doses of respectively 10 g/(kg·d) and 20 g/(kg·d) and also fed a high-fat diet.After 45 days of administration,serum total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C) and morphological changes in the liver of all the rats were examined.Results: SPRS could significantly reduce the contents of TC,TG and LDL-C,and increase the content of HDL-C in rat serum.Meanwhile,the liver degeneration and damage of the SPRS groups were markedly attenuated compared with the hyperlipidemia model group.Conclusion: SPRS has an excellent regulatory effect on blood lipid level and enhances the recovery of liver damage in rats with hyperlipidemia.
【Fund】: 四川省科技支撑计划项目(2009NZ0077-007)
【CateGory Index】: R589
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