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《Food Science》 2012-09
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Effect of Lactosucrose on Intestinal Development of Weaned Rats

HUANG Xiao-liu1,RUAN Zheng1,,ZHANG Mei-ying2,ZHOU Yan1,ZHANG Cui1,LI Ling1,YIN Yu-long1,3(1.State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China;2.Campus Hospital,Nanchang University,Nanchang 330031,China;3.Institute of Subtropical Agriculture,Chinese Academy of Sciences, Changsha 410125,China)  
Objective: To explore the effect of lactosucrose on intestinal development of weaned rats.Methods: Totally 24 weaned rats were randomly divided into 3 groups including normal group,lactosucrose group and Bifidobacterium group.The body weight of each rat at the 0,7th,14th,21st and 35th day and total food consumption per week were recorded.The spleen weight and the length of small intestine,the contents of SOD and MDA,ileum morphology and lymphcytes in the ileum were measured after all rats were killed at the 35th day.Results: The body weight at the 7th,28th and 35th day,the growth rate of body weight,the length of small intestine and lymphcytes in the ileum for rats treated with lactosucrose were significantly increased when compared with those of the rats from the normal control group(P0.05),and ileum MDA content was significantly lower than that in the rats from the normal control group(P0.05).Conclusion: Lactosucrose can improve intestine development of weaned rats.
【Fund】: 国家自然科学基金项目(31001014);; 黎介寿院士肠道屏障研究专项基金项目(LJS_201006)
【CateGory Index】: R151
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