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《Chinese Journal of Ecology》 2007-06
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Characteristics and safety of bar gene, PAT proteins and glufosinate

LIU Hong-yan, MI Xiao-ju, CUI Ji-zhe (Department of Biology, Harbin Normal University, Harbin 150025, China)  
As while as the development of transgenic technology creates enormous economic and social values, more attention has been paid to its safety. At present, the planting area of herbicide-resistant crops is the largest in transgenic crops. In this paper, the characteristics and safety of bar gene, PAT proteins and glufosinate were expatiated. The bar gene and glufosinate play important roles in plant engineering, and bar sequences are considered to be as safe as any other DNA in food and have no pleiotropism. As the products of bar gene, PAT proteins are devoid of adverse effects in mice, have no sequence homology with known toxins or allergens and no N-glycosylation sites, and do not possess the characteristics associated with food toxins or allergens by heat and digestive stability experiments. Therefore, they are safe for animal and human health. As a bio-herbicide, glufosinate can be rapidly degraded in soil, and has no remnants in mature crops and no toxic effect on mammals.
【Fund】: 黑龙江省教育厅科学技术资助项目(10551101)
【CateGory Index】: S332
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