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《Progress in Modern Biomedicine》 2015-32
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Influence of Abdominal Obesity on Severity of Coronary Artery Lesion in Patients with Acute Coronary Syndromes

ZHANG Xian;SHA Ming-lei;YAO Yu-ting;DAI Jia;NI Xiu-shi;Department of Geriatrics,First People's Affiliated Hospital of Shanghai Jiaotong University;  
Objective:To explore the influence of abdominal obesity on the severity of coronary artery lesion in patients with acute coronary syndromes(ACS).Methods:A total of 120 patients with ACS,who were treated in First People's Affiliated Hospital of Shanghai Jiaotong University from April 2012 to April 2013,according to the ratio of waist to height(RWH),were divided into 60 cases of non-abdominal obesity(as control group,RWH0.5),and 60 cases of abdominal obesity(as observation group,RWH0.5).Tthe basic data of the two groups were measured,and the RWH was calculated.The severity and the numbers of coronary artery lesion were judged by using coronary angiography.The coronary angiography results were evaluated by Gensini score.The correlation between the range of coronary artery lesion,Gensini score and RWH were analyzed.Results:The levels of SBP,FBG,TC,TG,LDL-C and Gensini score in the observation group were significantly higher than those in the control group,the differences were statistically significant(P0.05),but the HDL-C in the observation group was significantly lower than that in the control group,the difference was statistically significant(P0.05).Gensini score and RWH in the patients with two arteries lesions were significantly higher than those in the patients with single artery lesion,and Gensini score and RWH in the patients with three arteries lesions were higher than those in the patients with single artery and two arteries lesions,the differences were statistically significant(P0.05).Spearman correlation analysis showed that the range of coronary artery lesion and Gensini score were positively correlated with RWH(r=0.635,0.739;P=0.000,0.000).Conclusion:The high level of RWH in the patients with ACS is closely correlated with the severity of coronary artery lesion,therefore,so effectively controlling the abdominal obesity has an important significance in reducing the morbidity of cardiovascular disease and alleviating the severity of coronary artery lesion.
【CateGory Index】: R541.4;R589.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LIU Zhi,HUA Qi,TAN Jing (Department of Cardiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China);Analysis of clinical and coronary angiography of old women with acute ST-segment elevation myocardial infarction[J];Chinese Journal of Geriatric Heart Brain and Vessel Diseases;2012-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Chao-hua,TANG Jian-min,XIE Li-min The Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China;Effects of different doses of Atorvastatin on CRP、IL-6 in patients with acute myocardial infarction undergoing percutaneous coronary intervention[J];Journal of Medical Forum;2011-02
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