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《China Biotechnology》 2010-12
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An Assessment of the Inhibiting Effect of the Beijing Invasive Plant Solanum rostratum on Tumor ATPase

LIANG Qian-jin1,2 LI Cui-ni1,2 XIANG Jun1,2 LIU Quan-ru1,2 ZHOU Yun-long1,2SUN Le3 MAO Chun-ming3(1 College of Life Sciences,Beijing Normal University,Beijing Key Laboratory,Beijing 100875,China)(2 Key Laboratory of Cell Proliferation and Regulation Biology,Ministry of Education of China,Beijing 100875,China)(3 AbMax Biotechnology Co.,Beijing 100085,China)  
In Beijing,there has emerged an external invasion plant,Solanum rostratum dating from the beginning of this century.This plant originated from the North America.It is poisonous all over the body.There exists a sort of neurotoxin,solanine in Solanum rostratum.On the other hand,solanine is also a valuable material that,for example,is effective for inhibiting tumors.In order to utilize waste materials by obtaining pharmacologically and economically valuable products such as solanine from Solanum rostratum as well as becoming familiar with its toxic degree and tackling with this external invasion plant.It was designed to assess the tumor suppressing effect of Solanum rostratum by detecting the inhibiting effect of the whole-plant extract on the membrane ATPase activity of mouse tumor cell H22,with the functional effects of solanine and traditional chemotherapeutic cyclophosphamide as controls.The result revealed,in the nature of Beijing,the growing Solanum rostratum arising from invading expressed a tumor cell membrane ATPase activity inhibiting effect around as high as that of 3.63 mg/kg solanine,and around as high as or slightly higher than that of potato budlet equivalent.Therefore,it is possibly opportune to utilize waste material during renovating the ecology destroyed by the invading Solanum rostratum through obtaining medical components like solanine.It would be an economically efficient reaction,in the meanwhile emancipating the productive forces of potato and other valuable Solanum plants.
【Fund】: 北京市自然科学基金(8082016);; 北京市优秀人才培养资助基金(20081B0503100259);; 国家自然科学基金(30771101 30971470)资助项目
【CateGory Index】: S567.239
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Chinese Journal Full-text Database 2 Hits
1 WANG Qiu-ping1,2,LANG Lang1,2,JI Yu-bin1,2 (1.Center of Research on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin 150076, China;2.Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,Harbin 150076,China);Preliminary Study on Testicular Toxicity of Solanine to Male Mice[J];Food and Drug;2009-11
2 JI Yu-bin, WANG Sheng-hui, GAO Shi-yong, ZOU Xiang, JI Chen-feng (Postdoctoral Programme, Institute of Materia Medica, Harbin University of Commerce, Harbin 150076, China);Effect of Solanum nigrum total alkaloid on sialic acid and blocking degree of tumor cell membrane in H_(22) tumor-bearing mice[J];Chinese Traditional and Herbal Drugs;2005-01
Chinese Journal Full-text Database 10 Hits
1 JI Yu-bin , WANG Hong-liang ,GAO Shi-yong (Postdoctoral Program, Institute of Materia Medica,Harbin University of Commerce, Harbin 150076, China);Study on effect of solanine on activities of ATPase in tumor cell membrance[J];Journal of Harbin University of Commerce(Sciences Edition);2005-02
2 YANG Hui~1,CHEN Xiao-qing~(1),ZHAO Yu~2,XUE Xiao-juan~1 (1.Department of Chemistry and Chemical Engineering,Central South University,Changsha 410083,Hunan,China;2.ChangHong Medicine Research Company,Zhuhai 519085,Guangdong,China);Analysis of Steroidal Alkaloid and Research of Its Formation and Transformation in Solalum Nigrum L.[J];Fine Chemicals;2006-04
3 LI Chuan-gang~1, LI Mo-lin~2, SHU Xiao-hong~2, JIA Yu-jie~2, LIU Yong-ji~1 1.Department of Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian 116023, P.R.China 2.Dalian Medical University, Dalian 116027, P.R.China;Studies on the induction of apoptosis mediated Fas receptor by Sijunzi decoction on the mouse bladder carcinoma[J];Journal of Qilu Oncology;2005-20
4 Ji Yubing, Goo Shiyong (Research Center of Research and Development on Life Sciences and Environmental Sciences, Harbin Commercial University of Commerce,Harbin, 150076) Wang Hongliang,Zou Xiang (Postdoctoral Programme Work Station, the Institute of Materia-medico, of Harbin Commercial University, Harbin, 150076, China);The effect Effect of Total Alkaloids from Solanum nigrum on activities Activities of Na~+,K~+-ATPase and Ca~(++),Mg~(++)-ATPase in tumor Tumor cell Cell membranceMembrance[J];;2006-04
5 HUANG Hua,ZHOU Jian-hua(College of Life Science,Shandong Normal University,Jinan 250014,China);New research progress of solanum nigrum and its application[J];Science and Technology of Food Industry;2009-01
6 JIANG Xin-yu1,YANG Hui1,*,ZHAO Yu2(1.College of Chemistry and Chemical Engineering,Central South University,Changsha 410083,China;2.Changhong Medicine Research Company,Zhuhai 519085,China);The Determinnation of Steroidal Alkaloid Content in Solanum nigrum L[J];Food Science;2006-08
7 LUO Xi-zhen,CHEN Lai,LIU Jian-jun,YAO Peng-cheng(Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China);Determination of Solasodine in Solanum nigrum L. by High-performance Liquid Chromatography[J];Lishizhen Medicine and Materia Medica Research;2009-02
8 WANG Qiu-ping1,2,LANG Lang1,2,JI Yu-bin1,2 (1.Center of Research on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin 150076, China;2.Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,Harbin 150076,China);Preliminary Study on Testicular Toxicity of Solanine to Male Mice[J];Food and Drug;2009-11
9 ZHOU Yuan1,LIANG Zong-suo1,2 (1 College of Life Sciences,Northwest A&F University,Yangling,Shannxi 712100,China;2 Shaanxi Research Center in TCM Fingerprint & NP Library,Yangling,Shannxi 712100,China);Extraction methods of polysaccharides from the fermentation mycelium of Polyporus umbellatus[J];Journal of Northwest A & F University(Natural Science Edition);2008-06
10 Dan Luo,Li-Hong Ye,the First Clinical Medicine College, Nanjing University of Chinese Medicine,Nanjing 210029, Jiangsu Province,China;Current situation and prospects of experimental researches on treatment of hepatoma using traditional Chinese herbs[J];World Chinese Journal of Digestology;2008-26
China Proceedings of conference Full-text Database 1 Hits
1 ;Status of Study on Alkaloid of Solanum nigrum L.[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 WANG Guoping, LEI Qunfang (Department of Chemistry, Zhejiang University, Hangzhou 310027, China);Synthesis, characterization, antibacterial and antitumor activities of three gadolinium (III) complexes containing fluoroquinolones[J];Journal of Zhejiang University(Sciences Edition);2003-04
2 Tan Weidong,Jin Hong,Luo Dixiang,Zhoug Shaodong,Su Zhi,Peng Xudong,Gao Xiaoping (Chengdu Di Ao pharmaceutical Company of Academia Sinica,Chengdu 610041) ];COMPARISON OF MTT WITH SRB ASSAYS IN VITRO ANTICANCER DRUG SCREENING[J];Natural Product Research and Development;1999-03
3 WANG Shou lin,et al.School of Pubilic Health of Nanjing Medical University(Nanjing 210029);Effects of the Couple Exposures to the Mixed Benzene on Gestational Processes and Pregnancy Outcomes[J];China Public Health;2001-02
4 HAN Xiao-dong,WANG Xu-ying,SHEN Su-nan,et al Immunology and Reproductive Biology Laboratory,Medical School,Nanjing University,Nanjing,Jiangsu 210093,China;Effect of Nonylphenol on the Apoptosis of Rat Stertoli Cells in Vitro[J];China Preventive Medicine;2004-04
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