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《PROGRESS IN BIOTECHNOLOGY》 1996-03
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Metallothionein in Eukaryotic Microorganism

Lin Zhilan;Chang Limei(The College of Life Science, Peking University, Beijing, 100871, China)  
A review is reported on metallothionein (MT) from eucaryotic microbial sources with 45 refer ences. In yeast and fungi,cellular resistance to heavy metal cytotoxicity is mediated either by binding metal ions to proteins of the metallothionein type or by chelating to phytochelatin-peptides(PCs) of the general formula (γ-Gln-Cys)nGly. The present review involves yeast metallothionein sequence and metal-binding properties,the MTs and PCs structure and function as well as the structure of the feast CUP1 (MT genes),mechanismg of gene amplification and gene regulation,then,we describe the appli cation of the yesat MTs in medicine、metal recovery and that of CUP1 promoter in biotechnology.
【Fund】: 国家自然科学基金
【CateGory Index】: Q936
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【References】
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【Co-references】
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2 ZHANG Zhi-tao LIU Jin-sheng XU Qiang SUN Xiao-meng WANG Yi-peng(Department of Basic Medicine,Shandong Academy of Medical Sciences,Jinan,Shandong,250062,China);Protein determination of milk by Bradford method[J];食品与机械;2011-05
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5 WANG Ping, GE Li-hua (School of Forestry, Northeast Forestry University, Harbin 150040, Heilongjiang, China);STUDY ON ANTIOXIDATION OF FERULOYLATED OLIGOSACCHARIDES[J];食品研究与开发;2007-03
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【Secondary References】
Chinese Journal Full-text Database 9 Hits
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