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《Chinese Journal of Biologicals》 2012-01
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Progress in research on galanin receptor-2

ZHANG Dan*,YANG Chun(*Department of Nuclear Medicine,Wuhan General Hospital of Guangzhou Military Command,Wuhan 430070,China)  
Galanin receptor 2(GalR2) is one of the G-protein coupled receptors,of which the mRNAs are localized in hypothalamus,hippocampus,amygdale,several regions of cortex and dorsal root ganglion.Combined with Galanin,GalR2 participates the regulation of multiple physiological and pathological processes,including feeding,cognition,learning and memory,nociception,emotional reaction,inflammation and tumor,which may be served as a potential drug target for treatment of Alzheimer disease,anxiety,pain,metabolism syndrome and tumor.This paper reviews the structure and distribution of GalR2 as well as its relationship to diseases.
【CateGory Index】: Q516
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