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《Journal of Shanxi University(Natural Science Edition)》 2014-04
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Effects of 30~33℃ Mild Hypothermia on Hematology in Male BALB/c Mice

HUANG Liqun;LI Shufang;YUE Juan;LI Weibin;LI Youchen;AN Quan;Department of Radiation Medicine and Environment Medicine,China Institute for Radiation Protection;  
BALB/c mice were kept at mild hypothermia of 30~33℃ pentobarbital sodium assisted for 4h and then recovered to normal naturally.The blood of the mice was taken from the control group and the mild hypothermia group(at 2h,24 hand 72hsince recovery started)and analyzed on coagulation,biochemistry,cytology and electrolyte.The results showed that part of liver function index emerged a transient change at 2h,AST and ALT were higher than control group(P0.01),TP和 ALB were lower than the control group(P0.05),while ALP was lower than the control group all the time(P0.01 or P0.05);renal function index BUN,Cr and UA were higher than the control group(P0.01 or P0.05);erythrocyte index RBC,HGB,HCT%and MCHC rise up(P0.01 or P0.05);Na+,pH and Ca2+were higher than the control group(P0.01);there was no obvious change on coagulation index.We should pay attention to the influence to renal function index and erythrocyte index when use the mild hypothermia pentobarbital sodium assisted.
【Fund】: 山西省实验动物专项资金项目(2013(k07))
【CateGory Index】: R331
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