Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Proceeding of Clinical Medicine》 2013-07
Add to Favorite Get Latest Update

Effect of Ginkgolide C in cardiac function of rats in the body

ZHAO Ting,SU Zhong-ping,ZHU Li-li,Xu MAO-chun,ZHOU Dian,DONG Wei,HAO Yan-ling(Xuzhou Medical College,Xuzhou 221004,China)  
ObjectiveTo study the effect of Ginkgolide C(GC) in cardiac function of rats in the body.Methods : Normal rats after anesthetized,inserted the intubate which connecting the pressure transducer into left ventricular from the right common carotid artery,then detected the cardiac function by the PowerLab biological signal acquisition system.Gave each of saline,1‰dimethyl sulfoxide(DMSO),100 μ mol / L GC,1 000 μ mol / L GC 1ml from the jugular vein,detected the cardiac function before and after administration by continuous recording the left ventricular systolic pressure(LVSP),left ventricular end diastolic pressure(LVEDP),the maximal rate of pressure increase in systole phase(+dp / dtmax),maximal rate of pressure decrease in diastole phase(-dp / dtmax) and heart rate(HR).Results : Compared with normal conditions,when given 100 μ mol / L GC,there are no significant effect on cardiac function;when given 1 000 μ mol / L GC,it showed inotropic activity by increasing △LVP,+dp / dtmax,-dp / dtmax significantly,but had no significant effect on HR.Conclution : Ginkgolide C can increase△LVP significantly,enhances the myocardial systolic and diastolic function of rats,but has no significant effect on HR while it shows inotropic activity.
【Fund】: 江苏省大学生实践创新训练计划省级项目(项目编号:2012JSSPITP1857)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHOU Yuan-shen, ZOU Xu, PAN Guang-ming (Guangdong Province Hospital of Traditional Chinese Medicine, Guangzhou 510000, China);Progress of chronic heart failure in traditional Chinese medicine[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-11
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SHAN Bao-en,LI Jun-xin,ZHANG Jing,LIANG Wen-jie,LI Hong-fen(Science and Research Center,The Fourth Hospital of Hebei Medical University,Hebei Shijiazhuang050011,China);The Anti-tumor in Vitro Effect of Cortex Periplocae and Its Analogues Extracted[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-05
2 LU Wen-yun et al (College of Chemistry and Environment, Guizhou University for Nationalities, Guiyang, Guizhou 550025);Compared Analysis of Total Alkaloids and Polysaccharides in Tubing Shoot and Wild Plant of Dendrobium Loddigesii[J];Journal of Anhui Agricultural Sciences;2006-08
3 TIAN Shi-lin et al (Huanghuai University,Zhumadian,Henan 463000);Determination and Comparison of Chlorogenic Acid in Leaf and Bark of Cortex[J];Journal of Anhui Agricultural Sciences;2006-13
4 YIN Shuai-wen et al(College of Life Science,Jinggangshan University,Ji'an,Jiangxi 343009);Study on Traditional Poisonous Pteridophyte in Jinggangshan Region[J];Journal of Anhui Agricultural Sciences;2007-08
5 WU Gong-qing et al (Guangdong Pharmaceutical University, Guangzhou, Guangdong 510006);Study on the Extraction of Total RNA from Pinellia ternata (Thunb.) Berit Leaves[J];Journal of Anhui Agricultural Sciences;2008-08
6 ZHANG Xu et al(College of Agronomy,Sichuan Agricultural Universty,Yaan,Sichuan 625014);The Determination of Vitamins in the Leaf of Perilla L.by HPLC[J];Journal of Anhui Agricultural Sciences;2008-19
7 LI Jin-bu et al (Life Sciences College of Huaibei Coal Industry Teachers College,Anhui Biology Key Laboratory of Resource Plant,Huaibei,Anhui 235000);Studies on Bioactivity of Extracts from Pinellia ternata (Thunb.) Breit on Myzus persicae(Sulzer)[J];Journal of Anhui Agricultural Sciences;2009-09
8 ZHAO Hong-yan et al(Department of Life Sciences and Technology,Xinxiang University,Xinxiang,Henan 453000);Changes of Eucommia ulmoides Leaf in Organization Structure and Index Component Contents during Its Growth and Development Process[J];Journal of Anhui Agricultural Sciences;2009-14
9 XING Bing-cong et al(College of Forestry and Biotechnology,Zhejiang Forestry University,Hangzhou,Zhejiang 311300);Progress in Curcumin Derivatives form Curcuma wenyujin[J];Journal of Anhui Agricultural Sciences;2009-16
10 KONG Dong-mei et al(School of Life Science and Technology,Shanxi University,Taiyuan,Shanxi 030006);Study on the Diversity of Medicinal Seed Plant Resources in Pangquangou Nature Reserve[J];Journal of Anhui Agricultural Sciences;2009-33
China Proceedings of conference Full-text Database 7 Hits
1 Peiguang Pan The Affiliated Nanhai Maternity and Children Hospital of Guangzhou Traditional Chinese Medicine University;Foshan;Guangdong.China.528200;Magnolia powder applicated to fart after abdominal surgery for a multi-center,randomized,open,parallel clinical study[A];[C];2012
2 Zhang Chunhui,Wu Aiying,Wang Youlan (Qingdao Institute for Drug Control,Shandong Province,Qingdao 266071);Identification on Radix Puerariae thomsonii and its adulterant Radix Puerariae edulis[A];[C];2008
3 Lu Xiao-xia~1,Jiang Li-jia~1,Fan Jing~1,Wang Duo-qin~1,Tang Min~1,Xia Lei~1,Ma Ling-di~(1,*) 1 Changzhou Second Hospital,Nanjing Medical University,Changzhou 213003;2 The first clinical college,Nanjing Medical University,Nanjing 210029;Effect of matrine on proliferation inhibition and apoptosis induction in K562 cells in vitro[A];[C];2009
4 Wu Lihong,Wang Zhengtao (Shanghai R&D Center for Standardization of Chinese Medicines,Shanghai 201210,China; The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines,Institute of Chinese Materia Medica,Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China);Inheritance of Chinese Gentian Root[A];[C];2010
5 ;Analysis on cultivation influence on Genetic Diversity of authentic Glycyrrhiza uralensis[A];[C];2010
6 HAN Junhua,HE Mei,ZHOU Shengsheng,WANG Guodong,et al. Institute of Nutrition and Food Safety,Chinese Centre for Disease Control and Prevention,Beijing 100050,China;Analysis of phytosterol contents in food plant materials and Chinese traditional medidnes[A];[C];2009
7 WANG yongxia,WU xinjie REN linlin,WANG youping,WANG caige,ZHU mingjun, The First Affiliated Hospital of Henan TCM College,Zhengzhou(450003);Effect of Atherosclerosis Cured by Lipid Capsule on Rabbits[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 DING Bi yun, ZHOU Yi xuan, DAI Xiao hua,GU Jian xia, WANG Ling,DONG Mei,SHAO Zheng bin (The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine, Anhui Hefei 230031, China);Effect of Shenmai Injection Combined with Danshen Injection in Treating Congestive Heart Failure:A Report of 36 Cases[J];Journal of Anhui Traditional Chinese Medical College;2004-03
2 YAO Huai-fang, HU Ye-bing, CHENG Xiao-yu, WANG Jian, ZHANG Wan-dong, ZHANG Ye-xiang(Department of Myocardiology, the First Hospital Affiliated to Anhui College of Traditional Chinese Medicine, Anhui Hefei230031, China);Clinical Observation on the Effects of Wenshenyixin Pill in Treating Congestive Heart Failure[J];Journal of Anhui Traditional Chinese Medical College;2005-04
3 Cai Hui,Hu Wanying ( Nanjing general hospital of PLA, Nanjing 210002 );EFFECT OF LUJIAOFANG ON PLASMA ATRIAL NATRIURETIC FACTOR IN THE RAT WITH CONGESTIVE HEART FAILURE[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1999-02
4 DENG Yuan-jiang1,LIANG Wei-xiong2,LIU Wei-ying3,CHENG Shu-yi2,CHEN Yun-bo2 (1The first Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China;2 Center of DME,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China;3The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510080,China);Effect of Shengmai capsules on MMP-3&TIMP-1 of cardiac muscle in rats with chronic congestive heart failure[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-11
5 ZHANG Wan-yi,CHEN Wei-juan,QIU Yun-qing (Shengli Hosp.,Shengli Oilfield,Dongying 257055,China);Treatment of aging congestive heart failure with method of promoting and invigorating pectoral-qi[J];Shandong Journal of Traditional Chinese Medicine;2003-08
6 GE Hong qing 1,ZHAO Liang 1,HAO Li min 21.Guangzhou University of Traditional Chinese Medicine2.Zhongshan Medical University;Professor Deng Tietao's Experience in Treating Chronic Congestive Heart Failure Through Spleen[J];Shanghai Journal of Traditional Chinese Medicine;2002-04
7 LU Yong-yi1 WANG Sheng-lin2 DONG Yao-rong21. Service Center of Community Health in Fenglin Street, Shanghai2. Shanghai Municipal Hospital of Traditional Chinese Medicine;Treatment of 120 Cases of Contractile Heart Failure by “Heart-Strengthening Decoction”[J];Shanghai Journal of Traditional Chinese Medicine;2007-06
8 Zhang Yan1,Hai Li2,Song Tingting3,Pang Min3,Hu Xiaohong4 (1. The Affiliated Hospital of Liaoning University of TCM,Shenyang Liaoning 110032; 2. Beijing Nanyuan Hospital,Beijing 100076;3. Traditional Chinese Medicine Institute of Liaoning Province,Shenyang Liaoning 110034; 4. 705 Hospital of Shenyang Air Force Headquarters,Shenyang Liaoning 110015);The Research of Compound Formula Yiqihuoxue on PLT Activation in Chronic Heart Failure Rats[J];World Journal of Integrated Traditional and Western Medicine;2008-04
9 HUO(Yong-)fang,ZHANG Zhen,GUO Shi-da,et al.Shanghai 7th People Hospital,Shanghai 200137,China;Clinical Study on Treating CHF with HUAXINSU Granules by Polycentiric,Double Blind and Double Simulation.[J];Chinese Journal of Natural Medicine;2005-04
10 LIU Qiang~1,LI Meng~2,ZHONG Zhi-guo~1,LUO Lei-ling~1,WANG Bo-zhang~1(1.Affiliated Hospital of Guangdong Medical College Guangdong Zhanjiang 524001,China;2 Graduate Student of 2006 Grade in Guangdong Medical College Guangdong Zhanjiang 524023,China);Effects of Qiangxin Lishui Recipe on Nueroendocrine of Chronic Heart Failure in Rats[J];Chinese Journal of Basic Medicine in Traditional Chinese Medicine;2008-08
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved