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《Shaaxi Journal of Medical Laboratory Sciences》 2003-01
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Clinical Significance of Alanine Aminopeptidase and Leucine Aminopeptidase for Hepatobiliary Disease

WU Lin-Ian,LIN Tian-shou ,TU Xiang-dong (Center for Clinical Laboratory Sciences, FujianFuzhou General Hospital PLA,Fujian Fuzhou 350025 ,China)  
Objective To compare clinical significance of alanine aminopeptidase(AAP) and leucme aminopeptidase(LAP) activity in serum for hepatobiliary disease. Methods Determining AAP and LAP activity in serum of 159 cases of hepato-biliary disease subjects in the meantime. Results AAP and LAP activity in serum were significantly higher for hepatobiliary disease subjects. Values increasing by degrees in order were acute disease of biliary trait .primary carcinoma of liver,a-cute icteric hepatitis, cirrhosis of liver,metastasis hepatocarcinoma and chromcity hepatitis B.It showed highly significant correlation between AAP and LAP in serum,correlation coefficient was 0. 976 2,.P0. 01. Both of aminopeptidase were significant correlation with ALP and GGT. Conclusion Clinical value of AAP in serum is similar to LAP for hepatobiliary disease,both AAP and LAP are sensitive indicators of hepatobiliary disease.
【CateGory Index】: R446.1
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【Citations】
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