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《Journal of Shanxi Medical University》 2002-01
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In vitro study on interaction between levofloxacin hydrochloride for injection and its co-administrated drugs

ZHANG Shu qiu,LENG Guang,ZHANG Li feng (School of Pharmacy, Shanxi Medical University,Taiyuan 030001, China)  
Using thin layer chromatography and determining pH alteration, the solvents and commonly co administrated drugs with levofloxacin were studied in vitro. The results showed that both 10% glucose injection and 0 9% sodium chloride injection were good solvents for levofloxacin. The stability was acceptable when levofloxacin hydrochloride for injection was used with some common drugs. The numbers and position of thin layer spots and pH value did not change. This experiment could provide evidences for clinical practice.
【CateGory Index】: R942
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