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《Shaanxi Medical Journal》 2007-11
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Study of CD14 gene promoter region C-260T polymorphism in the Hans in Guangxi province

Xu Qunqing Wei Yesheng Liang Liyan Scientific Laboratory Center , Youjiang Medical College for Nationalities (Baise 533000)  
Objective: To study the allele frequencies and genotype distribution of CD14 gene promoter C-260T polymorphism in the Han ethnic groups in Guangxi province,and to analyze the distributions of CD14 polymorphism were among different races. Methods: The CD14 genotypes were examined by the polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) methods in 208 Han populations, frequencies of allele and genotype of CD14 polymorphism compared with other ethnics. Results: The frequencies of CC, CT and TT genotypes were found to be 32.2%, 46.6% and 21.2%;the frequencies of C、T allele were found to be 55.5% and 44.5% in the Hans populations. Compared with czech populations, the CD14 polymorphism was significantly different. Conclusion: There is a CD14 gene promoter C-260T polymorphism in the Hans in Guangxi, whose distribution is significantly different in different ethnic populations. The variation of CD14 gene polymorphism among different ethnic groups might account for the varied clinical spectrum of some CD14 related diseases.
【Fund】: 广西自治区科学基金资助项目(0447060 04009);; 广西自治区教育厅课题(200420);; 右江民族医学院科研基金资助项目
【CateGory Index】: R394
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【References】
Chinese Journal Full-text Database 1 Hits
1 Department of Clinical Microbiology and Immunology, Guiyang Medical College(Guiyang 550004) Jiang Hongmei Wang Yongxia;The linkage analysis of HLA-DRB_1 and polymorphisms of HLA-DM gene[J];Shaanxi Medical Journal;2008-09
【Citations】
Chinese Journal Full-text Database 1 Hits
1 WEI Ye-Sheng 1,LI Zhuang 1,LAN Jing-Sheng 2 1Clinical Laboratory Center, 2Department of Cardiovasology,Affiliated Hospital,Medical College for Youjiang Nationality,Baise 533000,China;Association of polymorphisms of transforming growth factor-beta 1 gene with susceptibility to essential hypertension in Zhuang nationality of Guangxi province[J];Journal of The Fourth Military Medical University;2005-04
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 WEI Ye-Sheng1, LIU Yun-Guang1, TANG Ren-Guang1, LAN Jing-Sheng21Center of Clinical Laboratory, 2Department of Cardiovasology, Hospital Affiliated to Youjiang Medical College for Nationalities, Baise 533000, China;Association between CD14 gene promo-ter region polymorphisms and coronary heart disease[J];Journal of the Fourth Military Medical University;2006-07
2 ZHAO Dan,ZHONG Hua,HE Fang.(Key Laboratory of Xinjiang Endemic and Ethnic Diseases Cooperated by Education Ministry with Xinjiang Province; Department of Pathophysiology,Medical College,Shihezi University,Shihezi 832002,China);Association of Transforming Growth Factor β_1 Gene Polymorphism with Cardiovascular Disease[J];Medical Recapitulate;2009-07
【Co-references】
Chinese Journal Full-text Database 6 Hits
1 YANG Wen-lin1, YANG Jian1, CHEN Sheng-qiang2, XIE Fang-ying1, HUANG Xin-yu1, YE Ting1 1Department of Dermatology, the Second Affiliated Hospital, 2Institute of Neurology, Guangzhou Medical College, Guangzhou 510260, China;HLA-DM gene polymorphism in Cantonese with condyloma acuminata[J];Journal of Southern Medical University;2006-07
2 LIUXiang yuan, MINWei qi, Huang Feng,Li Sheng guang(Department of Rheumatology, PLA General Hospital , Beijing 100853,China);Study on HLA-DM polymorphisms in patients with rheumatoid arthritis in Chinese population[J];Academic Journal of Pla Postgraduate Medical School;2002-01
3 ZHANG Yong,ZHU Xiao-chun,SUN Xue-qing(Medical College of Shanghai Jiaotong University,Shanghai Institute of Immunology,Shanghai 200025,China);Polymorphism of TAP,LMP and HLA-DM genes of Chinese Han population in Shanghai area[J];Current Immunology;2006-01
4 LIU Xiang yuan ,ZHU Ji ping,MIN Wei qi,HUANG Jian sheng. *Department of Rheumatology,PLA General Hospital,Beijing 100853,China;Expression of HLA-DM and-DR gene in rheumatoid arthritis patients in the Han nationality[J];Chinese Remedies & Clinics;2003-01
5 WE Fei, HUANG Han-tin , HUANG Zhen-lie, LI Lai-yu , LIANG Li-yan , CHEN Xue-min . Department of Environmental Hygiene, Tongji medical College , Huazhong University of Science and Technology , Wuhan430030, China;Relationship of trichloroethylene-induced medicamentosa Uke dermatitis to HLA-DMA and HLA-DMB[J];Chinese Journal of Industrial Hygiene and Occupational Diseases;2006-05
6 YE Dong-Qing, LU Wei, SHI Xiao-Ming et al. Department of Epidemiology, Anhui Medical University, Hefei 230032;Genetic polymorphisms of HLA-DM gene at the healthy Han nationality in Anhui[J];Chinese Journal of Immunology;2002-05
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Yan, WEI Ye-sheng, ZHANG Ping-an, WANG Ming, LI Xiao-yan, HUANG Cong-xin. Department of Laboratory Science, Renmin Hospital of Wuhan University, Wuhan 430060, China;The serum E-selectin level and the G98T and S128R polymorphisms of E-selectin in patients with acute myocardial infarction[J];Chinese Journal of Laboratory Medicine;2004-05
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