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《Shaanxi Medical Journal》 2008-01
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A Clinical Study of Extraintestinal Involvement after Rotavirus Enteritis in 65 Infants

Yuan Baoli Xiong Wei Department of Pediatrics,the Second Affiliated Hospital of Guangzhou Medical College (Guangzhou 510260)  
Objective: To study the clinical manifestations and the laboratory results of extraintestinal organ damage after rotavirus enteritis in infants. Methods: 148 children with acute diarrhea were hospitalized from October 2004 to March 2006, whose fecal samples were obtained. Enzyme linked immunosorbent assay(ELISA) was used to detect rotavirus(RV). According to the result of blood, the patients were divided into RV positive group(detected group,65 children) and RV negative group(control group,83 children). The differences between these two groups of extraintestinal organ(such as liver, heart, the central nervous system)damage were analyzed. Results: There was no difference between detected group and control group in age. The concentrations of ALT in detected group were higher than in control group, but there was no significant difference. The concentrations of CK-MB,LDH and AST were all higher in detected group(P0.05).The incidences of lower respiratory tract infection and the central nervous system involvement in detected group were significantly higher than those in control group(P0.05). The young,the higher incidences of heart injury. Conclusion: This study indicated that rotavirus can cause extraintestinal organ damage besides diarrhea, and heart injury is the most common.
【CateGory Index】: R725.1
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