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《Journal of Modern Oncology》 2010-02
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Study on the effects of radiotherapy combined with local endogenetic thermotherapy in patients with cancer and bone metastases

CHEN Hong,WANG Yong-gang,DING Yun-xia,LIN Xu,ZHANG Yong,JI Hua,KANG Bao-guo,LIU Yue Department of Oncology,Kunming General Hospital of Chengdu Military Command of PLA,Kunming 650032,China.  
Objective:To investigate the effects of radiotherapy combined with local endogenetic thermotherapy in treatment of cancer and bone metastases.Methods:Fifty patients with cancer and bone metastases were divided randomly into 2 groups,25 patients of control group were treated with radiotherapy only,25 patients of treatment group were treated with radiotherapy combined with local endogenetic thermotherapy.Total radiation dose was 30Gy/10 fractions,single prescription dose was 3.0Gy/fraction,5 fractions per week,treatment group was combined local endogenetic thermotherapy,temperature was controlled in 41℃-43℃,3-5 times per week for total 7-10 times.Response rates of bone pain relief and movement capacity were evaluated after treatment for 2 weeks in two groups.Results:Twelve patients in CR and 5 patients in PR,response rate of bone pain relief was 68.0% in control group of 25 patients with bone pain,17 patients in CR and 5 patients in PR,response rate of bone pain relief was 91.6% in treatment group of 24 patients with bone pain(P0.05).Response rates of movement capacity were 75.0% in control group and 100.0% in treatment group(P0.05).The side-effects in treatment group was not obviously increased than in control group.Conclusion:Radiotherapy combined with local endogenetic thermotherapy is a good method in treatment of cancer and bone metastases,the effect of treatment group is better than that of radiotherapy only.
【CateGory Index】: R738.1
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