Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Modern Oncology》 2015-10
Add to Favorite Get Latest Update

Clinical efficacy of intraperitoneal perfusion of compound matrine injection and cisplatin on malignant ascites

Jia Gang;Zhang Hongzhi;Jiang Huijuan;Department of Oncology,Henan University Huaihe Hospital;Department of Radiotherapy,Henan University Huaihe Hospital;  
Objective: To study the therapeutic efficacy of intraperitoneal perfusion of Compound Matrine injection and Cisplatin on malignant ascites. Methods: Forty- two patients of malignant ascites were randomly divided into treatment group and control group. 22 patients were treated with Compound Matrine injection and Cisplatin intraperitoneal perfusion( treatment group),and 20 patients were treated with Cisplatin intraperitoneal perfusion only( control group). The changes in volume of ascites and treatment side effects were observed. Results: The objective response rate( CR and PR) of treatment group and control group were 90. 9% and 65. 0% respectively,and the difference was significant( P 0. 05). The treatment group had a slighter side effect on abdominal pain,gastrointestinal rection and bone marrow depression,and the difference was significant( P 0. 05). Conclusion: The results suggest that intraperitoneal perfusion of Compound Matrine injection and Cisplatin is safe and effective in treating malignant ascites.
【CateGory Index】: R730.58
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 5 Hits
1 Qi Xianyin;Liu Minjie;Department of Thoracic Surgery,Laiwu Hospital Affiliated to Taishan Medical College;;Effects of compound Matrine injection on the immunologic function of patients with lung cancer undergoing chemotherapy after resection[J];Journal of Modern Oncology;2014-01
2 Dai Xi;Yang Xiaoqiong;Respiratory Department 1,Affiliated Hospital of Luzhou Medical College;;The progress of single traditional herbal medicine treatment research in tumor[J];Journal of Modern Oncology;2014-02
3 TANG Xi,XU Yan-hua(Jingzhou Hospital,Tongji Medical College of Huazhong University of Science and Te-chnology,Jingzhou 433000,China) HU Ya(Changjiang University Medical College,Jingzhou 433000,China) QIU Hong(Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China);Efficacy Observation of Abdominal Indwelling Catheter Combined with Compound Sophora flavescens Injection and Cisplatin for Malignant Peritoneal Effusion[J];China Pharmacy;2011-28
4 TIAN Juan1,2,WANG Wei-hao1,GAO Hui-min1,WANG Zhi-min1(1.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;2.College of Life Science,Northwest Sci-Tech University of Agriculture and Forestry,Yangling 712100,China);Determination of matrine,sophoridine and oxymatrine in compound Kushen injection by HPLC[J];China Journal of Chinese Materia Medica;2007-03
5 ;Clinical study on treating advanced ovarian cancer with compound Kushen injection plus chemotherapy[J];Clinical Journal of Chinese Medicine;2011-05
Chinese Journal Full-text Database 10 Hits
1 DAI Wu-hao1,QIAN Li-wu2,YANG Shi-you3,ZHOU Guo-qin2(1.College of Pharmacy,Anhui College of Traditional Chinese Medicine,Hefei,Anhui 230031,China;2.Anhui Institute of Materia Medica,Hefei,Anhui 230022,China;3.Center for Drug Evaluation in Anhui Province,Hefei,Anhui 230022,China);Advance in pharmaceutical research of main alkaloid in Sophora flavescens and Sophora tonkinensis[J];Anhui Medical and Pharmaceutical Journal;2011-09
2 FAN Xiangling GUO Jinli LIU Yan Department of Gynecology,the Second Hospital of Beijing,Beijing 100031,China;Clinical observation of treating advanced gynecological malignancy with compound Kushen injection[J];China Medicine and Pharmacy;2011-20
3 GAO Yingchun(The People's Hospital of Pengzhou,Sichuan Pengzhou 611930,China);Clinical Observation on Treatment of the Locally Advanced Non-small Cell Lung Cancer with Compound Kushen Injection and Chemotherapy[J];Hebei Medicine;2011-12
4 HUANG Zhi-wen,ZHANG Hong-yan,ZHANG Kai,GAO Lei-shan(Author unit:Department of respiration,Renhe Hospital of Three Gorges University,Hubei Yichang 443001,China);The Clinical Research of Compound Kushen Injection and Corynebacterium Parvum as a Local Therapy for Patients with Advanced Lung Cancer Associated with Malignant Pleural Effusion[J];Journal of Clinical Pulmonary Medicine;2012-03
5 HUA Hai-qing,JIANG Zi-yu,YANG Ai-zhen,QIN Shu-kui.Center of Oncology,Nanjing 81 Hospital of PLA,Nanjing 210002,China;The effect of Fufangkushen injection alone and the combined effect with oxaliplatin for antiproliferative and apoptotic action on human hepatoma cell line SMMC-7721[J];Chinese Clinical Oncology;2010-01
6 SUN Yang1,XU Ying-ming1,QIN Dong-mei2,QIN Xu1,DAI Xiao-hua1 (1.Department of Pollution Control,Institute of Agro-Environmental Protection,Ministry of Agriculture of China,Tianjin 300191,China;2.Institute for the Control of Agrochemicals,Ministry of Agriculture,Beijing 100026,China);Residue Detection and Degradation of Matrine in Cucumber and Soil[J];Journal of Agro-Environment Science;2010-04
7 LIU Ying-hua1,ZHANG Xiao-wei2,LIU Li-na3(BaoDingShi first center hospital 1 electroencephalogram room,2 tumor medicine,3 eastern hospital the electrocardiogram Heibei,071000);Compound Kushen injection combined with cantharides sodium vitamin B6injection in the treatment of malignant pleural effusion clinical observation[J];Chinese Journal of Aesthetic Medicine;2012-18
8 SU Peng-fei;LI Wei;DUAN Dong-kui;JIN Zhe;Department of Thoracic Surgery,Nanyang City Center Hospital;;The Effect of Shiquandabu Decoction together with Enteral Nutrition for Patients with Lung Cancer after Surgery[J];Journal of Nanjing University of Traditional Chinese Medicine;2015-01
9 ZHAO Di;DENG Jie;ZHU Yan-ting;SHI Dao-hua;College of Pharmacy,Fujian University of Traditional Chinese Medicine;Department of Pharmacy,Fujian Provincial Maternal and Child Health Hospital;;Systematic Review of Traditional Chinese Medicine Combined with TP Regimen in Treatment of Advanced Ovarian Cancer[J];Strait Pharmaceutical Journal;2015-01
10 LI Zhen,FU Zhi-quan,LI Chun-xia,et al.Department of Digestion,the Third People′s Hospital of Hangzhou,Hangzhou 310009,China;Inhibition Effects of Compound Radix Sophorac Flavescentis Injection on Proliferation of Human Gastric Cancer BGC-823 Cells[J];Chinese General Practice;2011-21
China Proceedings of conference Full-text Database 1 Hits
1 Weiru Xu;Hongsheng Lin;Ying Zhang;Xinyi Chen;Baojin Hua;Wei Hou;Xin Qi;Yingxia Pei;Xiaoyun Zhu;Zhizheng Zhao;Liangliang Yang;Oncology Department,Guang An Men Hospital,China Academy of Chinese Medical Sciences;Department of Hematology and Oncology,Dong Zhi Men Hospital Affiliated to Beijing University of Chinese Medicine;Endocrinology Department,Guang An Men Hospital,China Academy of Chinese Medical Sciences;;Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ZENG Xiao Li1, TU Zhi Guang2 1.Clinical Laboratory of Anzhen Hospital,Capital University of Medical Sciences, Beijing,100029, P.R.China 2.Department of Clinical Biochemistry,Chongqing University of Medical Sciences, Chongqing,400016, P.R.China;Induction of Differentiation by Ginsenoside Rh_2 in Hepatocarcinoma Cell SMMC-7721[J];Chinese Journal of Cancer;2004-08
2 Zhitu ZHU1,Yunlong YU1,Kai WANG1,Enze LI1,Yangyang LIU1,Yunpeng LIU2 1Department of Oncology,the First Affiliated Hospital of Liaoning Medical University,Jinzhou 121001,China;2Department of Medical Oncology,the First Affiliated Hospital of China Medical University,Shenyang 110001,China;Effect of Bufalin on Proliferation and Apoptosis of Human Non-small Cell Lung Cancer A549 Cell[J];Chinese Journal of Lung Cancer;2010-09
3 CAO Hong,WEI Ping (Institute for Drug and Instrument Control Health Dept GLD of PLA,Beijing 100071);HPLC Determination of Matrine in Matrine Phosphate Injection[J];Pharmaceutical Journal of Chinese People's Liberation Army;2000-06
4 HUA Hai-qing,JIANG Zi-yu,YANG Ai-zhen,QIN Shu-kui.Center of Oncology,Nanjing 81 Hospital of PLA,Nanjing 210002,China;The effect of Fufangkushen injection alone and the combined effect with oxaliplatin for antiproliferative and apoptotic action on human hepatoma cell line SMMC-7721[J];Chinese Clinical Oncology;2010-01
5 WANG Bing, WANG Guo jun,CAI Xiong,et al.Department of Medical Oncology,Shanghai Sixth People's Hospital,Shanghai 200233,China;Inhibitory Effect of Oxymatrine on Vascular Endothelial Cell Proliferation Induced by Hepatocellular Carcinoma Cell[J];Journal of Qilu Oncology;2003-07
6 Li Rong,Liu Ming-hua,Xiao Shuan-han,Xie Wei-rong,Cao Yang,Ren Mei-ping(Laboratory of pharmacology and toxicology,Luzhou Medical College Luzhou Sichuan 646000);Reversal effect of irisquinone on COC1/DDP cell[J];Sichuan Journal of Physiological Sciences;2009-02
7 SHI Song-Lin 1),LI Qi-Fu 1),LIU Qing-Rong 1),XU Dong-Hui 2),TANG Jian 1),LIANG Ying 1)(1)Key Laboratory,Ministry of Education for Cell Biology and Tumor Cell Engineering,School of Life Sciences,Xiamen University,Xiamen 361005,China;2)Department of Hepar Biliary Pancreas Vascular Surgery,Affiliated Xiamen First Hospital,Fujian Medical University,Xiamen 361005,China);Differentiation Induced by Ginsenoside Rg1 Combined Formula Involved the Alteration of Prohibitin Localization and Expression in Human Osteosarcoma MG-63 Cells[J];Chinese Journal of Biochemistry and Molecular Biology;2008-02
8 YANG Qin,ZHANG Ya-shengDepartment of Traditional Chinese Medicine,the First People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China.;Effects of matrine injection on expressions of mRNAs and proteins of VEGF and CXCR4 in gastric carcinoma SGC-7901 cells[J];Journal of Modern Oncology;2010-08
9 WANG Bing1,WANG Guo-jun2,XU Jun1(1.Department of Radiotherapy,Shanghai Sixth Hospital,Shanghai,200233,China; 2.Department of Infection,Changzheng Hospital,Second Military Medical University,Shanghai,200003,China);Inhibitory effect of Oxymatrine on vascular endothelial cell proliferation induced by tumor[J];JOURNAL OF PRACTICAL ONCOLOGY;2000-05
10 ZHANG Zhen-ling,WANG Lei,WU Xiao-jing,ZHANG Hui-xia(Henan College of Traditional Chinese Medicine,Zhengzhou 450008,China);The Study About Immunocompetence of Polysaccharide of Radix Ranunculi Ternati[J];Lishizhen Medicine and Materia Medica Research;2007-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved