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《Journal of Modern Oncology》 2017-06
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Meta- analysis of image- guided brain tumor resection

Li Wenfei;Niu Chen;Guo Liping;Liang Fengli;Ma Xueying;Zhao Enfa;Zhang Yafei;Zhang Ming;Department of Radiology,First Affiliated Hospital of Medical College of Xi 'an Jiaotong University;Department of Ultrasonography,Second Affiliated Hospital of Medical College of Xi'an Jiaotong University;Department of General Surgery,Second Affiliated Hospital of Medical College of Xi'an Jiaotong University;  
Objective: We did a Meta- analysis to evaluate the effect of image- guided brain tumor resection and contrast traditional surgical treatment. Methods: We searched randomized controlled studies in Pub Med,CBM,Cochrane library,Web of Science database to November 15,2014. Using Rev Man 5. 3 software to analyze data. To calculate the odds ratio( OR) and 95% confidence intervals,test heterogeneity of source,use funnel plot to assess publication bias. Results: 10 randomized controlled studies( RCT),a total of 669 patients,including image- guided surgery 329 cases,340 cases of traditional surgery. Meta- analysis showed that: Compared with traditional surgery,image- guided brain tumor resection total resection rate was higher,the low incidence of postoperative dysfunction,the difference was statistically significant( P 0. 05). In total removal rate there was no significant difference( P 0. 05) between different image navigation. But in terms of postoperative dysfunction,intraoperative MRI was superior to ultrasound,ultrasound superior to DTI( P = 0. 02). Conclusion: Imaging navigation brain tumor resection compared to conventional surgery can improve the rate of total resection of the tumor,protect functional area,reduce the incidence of postoperative complications and improve the patient's life quality.
【CateGory Index】: R739.41;R445;R730.44
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