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《THE PRACTICAL JOURNAL OF CANCER》 1997-03
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The Effects of Cinnamic Acid on Proliferation and Nucleolar Organizer Regions of PGCL3 Human Lung Cancer Cell

Huang Wei, Hu Meixiang (Cancer Research Institute, Guangzhou Medical College, Guangzhou, 510182)  
This study is intended to investigate the anticancer effects of the low toxic flavorings cinnamic acid on PGCL3 human lung cancer cell subine. The results show that cinnamic acid at concentrations of 1 mmol/L and 3 mmol/L can obviously inhibit proliferation of PGCL3 human lung cancer cells ( P 0.05 to P 0.01 ). The suppressive rate was up to 48.6%. At the same time, the nucleolar forming rate was markedly decline (the mean number of nucleolus in each cell from 2.92 reduced to 1.66 and 1.96 ) ( P 0.01 ) and the number of particle of AgNOR in nucleolus markedly decrease from 39.26±7.49 reduced to 9.54±4.61 and 19.68±10.48 ( P 0.001 and P 0.01). These results showed that cinnamic acid is an efficient inhibitor of PGCL3 cell, and has potential use in cancer intervention.
【CateGory Index】: R73-3
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【References】
Chinese Journal Full-text Database 8 Hits
1 LUO Nian-hua;ZHENG Da-gui;ZHOU An-xi;WANG Yong;LIU Wen-jie;YOU Chong-ren;Key Laboratory of Applied Organic Chemistry,Higher Institutions of Jiangxi Province,Shangrao Normal University;;Dimethylacetamide-Promoted Synthesis of Substituted Cinnamyl Morpholine[J];精细化工;2016-08
2 YANG Jia-qiang;LEI Jing;LI Gang;WAN Xiao-qiang;School of Pharmacy, Zunyi Medical College;;Synthesis and antitumor activity of cinnamoyloxy phosphonate derivatives[J];药学学报;2016-03
3 LI Xiao-fang;FENG Xiao-qiang;YANG Sheng;Central laboratory of College of Life Science and Chemistry,Tianshui Normal University;Dingxi Teachers' College;;Interaction Mechanism between Cinnamic acid-La(Ⅲ) Complex and Herring Sperm DNA[J];天然产物研究与开发;2015-04
4 ZUO Ming-ming,ZHOU Jian-min,HU Guo-hui,JIANG Ji-miao,LI Xiao-kun(Wenzhou Medical College Pharmacy Shool,Zhejiang Wenzhou 325035,China);Synthesis and Anti-tumor Activities in Vitro of Cinnamic Amide Compounds[J];化学世界;2012-04
5 YANG Hui,GAO Wu-en,QING Mei(Department of pharmacy,Inner Mongolia Medical College,Hohhot 010059 China);SYNTHESIS OF ZALCITABINE DERIVATIVES[J];内蒙古医学院学报;2010-02
6 YANG Hui,Buren,JIANG Hong,et al.(Department of Medicinal Chemistry,Inner Mongolia Medical College, Hohhot 010059 China);SYNTHESIS OF N-METHYLEPHEDRINE SUBSTITUTED CINNAMIC ESTERS[J];内蒙古医学院学报;2006-02
7 JING Hui-ping~1,GAO Wu-en~3,WANG Dong-mei~2(1.School of Chemical Engineering,Inner Mongolia University of Techonology,Hohhot 010051,PRC;2.School of Pharmacology,Inner Mongolia University of Medicine,Hohhot 010059,PRC);SYNTHESIS AND CHARACTERIZATION OF CINNAMIC ACID NUCLEOSIDE ESTER DRUGS[J];内蒙古工业大学学报(自然科学版);2006-01
8 HUANG Wei,HUANG Ji qun,ZHANG Dong fang,et al. Cancer Research Institute,Guangzhou Medical College,Guangzhou,510182;Differentiation of BEL-7402 Human Hepatocarcinoma Cells Induced by Cinnamic Acid[J];实用癌症杂志;2000-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zheng Dagui;Zhou Anxi;Zhu Xianhong;Zheng Hongfu;Sun Xiangqian;Key Laboratory of Applied Organic Chemistry, Higher Institutions of Jiangxi Province,Shangrao Normal University;;An Efficient Dimethylacetamide-Promoted Conversion of Alcohols to Alkyl Chlorides[J];有机化学;2016-01
2 YANG Jia-qiang;LIU Si-lan;CHE Wan-li;ZHANG Mao-sheng;WAN Xiao-qiang;JIAN Hong-lu;CHEN Yong-zheng;School of Pharmacy, Zunyi Medical College;;Design, synthesis and antitumor activities of novel E-substituted 2, 3-diaryl propenoic acyloxy phosphonate derivatives[J];药学学报;2015-04
3 ZHU Fa-di;XIE Xue-wen;LI Jian-ming;GU Zu-min;LI Bao-ju;Plant Protection College,Shenyang Agricultural University;Institute of Vegetables and Flowers,Chinese Academy of Agricultural Sciences;;Control Efficacy of 5% Dimethomorph DPC on Cucumber Downy Mildew[J];中国蔬菜;2015-02
4 Yang,Jiaqiang;Ma,Jun;Che,Wanli;Li,Minggang;Li,Gang;Song,Baoan;School of Pharmacy, Zunyi Medical College;Center for Research and Development of Fine Chemicals, Guizhou University;;Microwave-Assisted Synthesis and Antitumor Activity of Salicyl Acyloxy Phosphonate Derivatives[J];有机化学;2014-12
5 YANG Jia-qiang;CHE Wan-li;MA Jun;LI Ming-gang;School of Pharmacy,Zunyi Medical College;;Synthesis and Bioactivity of Quinolone Derivates Containing Carboxylic Ester[J];精细化工;2014-04
6 Song Yan;Tian Zhensheng;Liu Zhenming;Liu Yu;Jilin Institute of Chemical Technology;Research Institute of Jilin Petrochemcial Company,PetroChina;;Research on synthesis of N-acryloyl morpholine[J];弹性体;2014-01
7 Yang,Jiaqiang;Gu,Qing;Hu,Yuewei;Shu,Bo;Song,Baoan;Liu,Jingzi;School of Pharmacy,Zunyi Medical College;Department of Biochemistry and Molecular Biology,Zunyi Medical College;Center for Research and Development of Fine Chemicals,Guizhou University;;Synthesis of O,O'-Dialkyl-α-phenyl-α-phenylsulfonyloxy- methylphosphonate under Ultrasound and Their Antitumor Activity[J];有机化学;2013-10
8 GAO Jun (Daqing Research Institute of Oil Refining Company,Daqing 163411,China);Study on synthesis of N-acryloymorpholine[J];应用化工;2013-08
9 DOU Yan-rong,HU Jian,HUANG Ming-gang(Sichuan College of Chemical Technology,Luzhou 646005,China);Improved on Synthesis of Dimethomorph with Sodium Hydroxide Alkali[J];化工技术与开发;2013-08
10 Yang,Jiaqiang*,a Gu,Qinga Shu,Bob Song,Baoanc Liu,Jingzia(aSchool of Pharmacy,Zunyi Medical College,Zunyi 563003)(bDepartment of Biochemistry and Molecular Biology,Zunyi Medical College,Zunyi 563003)(cCenter for Research and Development of Fine Chemicals,Guizhou University,Guiyang 550025);Synthesis and Antitumor Activity of O,O'-Dialkyl-α-phenyl-α(substituted benzoylanoxy)-methylphosphonate[J];有机化学;2013-05
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 FAN Yu-jiao;CHEN Hui-qin;MEI Wen-li;XU Shu-hui;ZHOU Li-man;HUANG Mian-jia;DAI Hao-fu;Institute of Tropical Agriculture and Forestry, Hainan University;Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences;Department of Pharmacy, Haikou People's Hospital;;Amide Alkaloids from the Seeds of Clausena lansium and Their Nematicidal Activities[J];热带亚热带植物学报;2018-01
2 LUO Nianhua;WANG Yong;ZHONG Yuhong;CAI Jiubiao;ZHU Shuntao;ZHENG Jie;School of Chemistry and Environmental Science,Shangrao Normal University;Educational Technology & Expenimental Center,Shangrao Normal University;The Second Middle School of Xinjian;;Synthesis and Characterization of (S)-(1-methylpyrrolidin-2-yl)-methanol[J];上饶师范学院学报;2017-03
3 DUAN Zhi-fang;SHAO Ling;LI Xin-chang;College of Life Science,Zhaoqing University;;Synthesis of Thioureido Cinnamic Acyl Thiourea Derivatives as Plant Exogenous Antioxidants[J];安徽农业科学;2017-09
4 LU Dong-wei;WU Xiao-yu;XIE Xian;YU Kai-li;LIN Cui-wu;College of Chemistry and Chemical Engineering,Guangxi University;Guangxi Colleges and Universities Key Laboratory of Applied Chemistry Technology and Resource Development;;Synthesis of Two Cinnamic Oxime Ester Derivatives and Their Interaction Mechanism with Human Serum Albumin[J];发光学报;2017-03
5 DUAN Zhi-fang;SHAO Ling;LI Xin-chang;College of Life Science,Zhaoqing University;;Synthesis of thiourea benzoylthiourea derivatives as exogenous antioxidants and their plant growth-promoting effects[J];广东农业科学;2017-03
6 GU Yun-qiong;ZHONG Yi-ning;SHEN Wen-ying;XIE Xin-chuang;TAN Ming-xiong;The Key Laboratory Cultivate Base of Guangxi for Agricultural Resources Chemistry and Efficient Utilization,Yulin Normal University;The Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources,Guangxi Normal University;College of Pharmacy of Guangxi University of Chinese Medicine;;Natural Product Tryptanthrin Halogenated Derivatives and Its Fe(Ⅱ)Complex:Synthesis,Cytotoxicity,and Bound G-quadruplex DNA[J];化学世界;2017-02
7 TIAN Wei;DOU Yawei;WANG Hongtao;ZHU Jianfei;DAI Yunluo;XIANG Hui;Shaanxi Provincial People's Hospital;;Effect of Chlorogenic Acid on Lung Cancer A549 Cell Apoptosis and Mechanism[J];解放军预防医学杂志;2016-06
8 ZHU Xian-hong;ZHOU An-xi;LUO Nian-hua;PENG Liang;ZENG Xian-zhu;ZHENG Da-gui;Key Laboratory of Applied Organic Chemistry,Higher Institutions of Jiangxi Province,Shangrao Normal University;;N,N-Dimethylacetamide-promoted Synthesis of Cinnamyl Carboxylate and The Co-promoted Mechanism[J];合成化学;2017-02
9 YANG Jia-qiang;ZENG Fa-kun;YANG Xuan;LI Peng;School of Pharmacy,Zunyi Medical College;Chemistry Department,University of Manitoba;;Synthesis and antitumor activity of phosphonate derivatives containing amino acid[J];药学学报;2016-07
10 ZHONG Yi-ning;WU Shi-yun;ZHANG Yan;LIU Huan;QIN Feng-mei;CHEN Yi-wei;Guangxi University of Chinese Medicin;;Determination Method Researchof Total Flavonoids in Nonvolatile Part of Cinnamomum cassia Presl[J];时珍国医国药;2016-03
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