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《Laboratory Animal Science & Management》 2006-02
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Study on the Genetic Diversity Among Rhesus monkey from Hainan and Guangxi by Using Microsatellite Markers

JI Fang,RAO Jun-hua,LIU Xiao-ming(Primate Research and Development Center of South-China,Institute of Endangered Animals,Guangzhou 510555,China)  
Objective To analyse genetic diversity among Rhesus monkey from Hainan and Guangxi by using microsatellite DNA.Methods Eleven microsatellite loci were tested for the rhesus monkeys from Hainan and Guangxi.Allele frequency,number of effective alleles(Ne),polymorphism information contents(PIC) and heterozygosity(H) for every microsatellite locus were calculated by softwrare Popgene32.Results All eleven microsatellite loci were highly polymorphic with heterozygosity ranging from 0.7066 to 0.9025,polymorphism information content from 0.5143 to 0.8270 and number of effective alleles from 3.0000 to 7.1553.Mean values of Ne、PIC and H for Guangxi rhesus monkeys were a little higher than those for Hainan respectively.Conclusion The differences could be attributed to the different geographic origins of two populations.This study laid out a theoretical foundation for further analysis of the genetic diversity among rhesus monkeys by using microsatellite markers.
【Fund】: 药物非临床安全评价(GLP)所需实验动物—SPF实验动物猕猴新品系的研究开发(C12101);; 广东省昆虫研究所青年基金项目
【CateGory Index】: Q953
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