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《Journal of Practical Radiology》 2005-10
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The Primary Study of Multi-slice Helical CT Perfusion in Nasopharyngeal Carcinoma

JIN Guan-qiao,SU Dan-ke,ZHU Xiao-dong,XIE Dong,HUANG Chen-yang(CT Department,the Affiliated Tumor Hospital of Guangxi Madical University,Nanning 530021,China)  
Objective To study the value of CT perfusion in differential diagnosis of local recur and local radiofibrosis of nasopharyngeal carcinoma(NPC) at pre-and post-radiotherapy.Methods Dynamic CT scan was performed in 71 objectives: 14 in local recur group,22 in radiofibrosis group,15 in pre-radiotherapy NPC group and 20 in control group,the time-density curve(TDC) and the data of perfusion parameters were recorded and analyzed statistically.Results The TDC feature between local recur group,pre-radiotherapy NPC group and radiofibrosis group,control group had difference.The average of blood flow(BF) had significant differences by two by two comparison in four groups(P0.01).Except for the control group and radiofibrosis group,the average of blood volume(BV)and permeability surface(PS) had statistical differences(P0.05).While in mean transit time(MTT),the significant difference between the control group and other three groups was only found(P0.01).Conclusion The TDC and perfusion parameters of local different structures of pre-radiotherapy and post-radiotherapy NPC are of different characteristics,which are helpful for the differential diagnosis of post-radiotherapy local recurrence and local radiofibrosis.
【Fund】: 广西应用基础科学基金资助(No:桂科基0448067)
【CateGory Index】: R739.63;
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