Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Practical Radiology》 2008-02
Add to Favorite Get Latest Update

Comparative Study of CT Perfusion and Pathologic Findings in the Model of Rabbit Nasopharyngeal VX_2 Tumors and Human Nasopharyngeal Carcinoma

ZHANG Jun,SU Dan-ke,JIN Guan-qiao,Liu li-dong (Imaging Center,the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021,China)  
Objective To investigate the characteristics of the CT perfusion between rabbit nasopharyngeal VX2 tumor(RNVX2T) and human nasopharyngeal carcinoma(HNPC),and to study the correlation of CT perfusion parameters with tumor microvascular density(MVD) of pre-and post-radiotherapy in RNVX2T.Methods The CT perfusion features of 15 pre-treatment patients with HNPC,the CT perfusion and pathology appearances of 8 cases of pre-and post-radiotheraphy RNVX2T models were analyzed comparatively and respectively.Results(1)The values of blood flow(BF),blood volume(BV),permeability surface(PS) and MVD of RNVX2T pre-radiotheraphy were statistically higher than those of post-radiotheraphy.The values of BF,BV and PS of RNVX2T pre-and post-radiotheraphy were positive linear correlations with those of MVD.(2).The values of BF,BV and PS between RNVX2T and HNPC had no statistical difference(P0.05).Conclusion The parameters of CT perfusion can be regarded as a surrogate index of tumor angiogenic activity pre-and post-radiotherapy in nasopharyngeal carcinoma.
【Fund】: 广西应用基础科学基金资助(编号:桂科基0448067)
【CateGory Index】: R739.63
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 6 Hits
1 ZHANG Jingfeng, WANG Renfa, WANG Min,et al. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University ofScience and Technology, Wuhan, Hubei Province 430030, P. R. China;Comparative Study of Multi-slice Spiral CT Perfusion and Pathological Findings in VX2 Soft-tissue Tumors of Rabbits[J];Journal of Clinical Radiololgy;2005-05
2 HUANG Biao, LIANG Changhong, ZHANG Yunting, et al. Department of Radiology, Guangdong Provincial People′s Hospital, Guangzhou,Guangdong Province 510080, P. R. China;Correlation Study Between CT Perfusion and Tumor Microvascular Density in Rabbit VX2 Soft-tissue Tumor[J];Journal of Clinical Radiololgy;2005-08
3 HUANG Biao, LIANG Chang-hong, ZHANG Yun-ting, ZHOU Dong, LIN Hua-huan, RU Guang-teng, LIU Hong-jun, LIU Qi-shun(Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080,China);The Correlative Study Between CT Perfusion Imaging and Microvascular Density of Astrocytoma[J];Journal of Practical Radiology;2005-05
4 JIN Guan-qiao,SU Dan-ke,ZHU Xiao-dong,XIE Dong,HUANG Chen-yang(CT Department,the Affiliated Tumor Hospital of Guangxi Madical University,Nanning 530021,China);The Primary Study of Multi-slice Helical CT Perfusion in Nasopharyngeal Carcinoma[J];Journal of Practical Radiology;2005-10
5 KANG Li-qing*, ZHANG Yun-ting, SUN Shi-mei. *Department of Radiology, General Hospital, Tianjin Medical University, Tianjin 300052, China;Tumor angiogenesis in rabbit VX2 brain tumor: model establishment,pathologic study and preliminary imaging observation[J];Chinese Journal of Radiology;2005-03
6 JIANG Hui jie 1* , XU Ke 1, LIU Rui bao 2, ZHANG Hui bo 1, WANG Qiang 1, GUO Min 1 (1.Department of Radiology, the Second Affiliated Hospital of Chinese Medical University, Shenyang 110001, China; 2.Department of Radiology, the Third Affiliated Hospital of Harbin Medical University, Harbin 150040, China);Experimental study on hemodynamic changes in liver before and after rabbit VX2 liver tumor inoculation by perfusion CT[J];Chinese Journal of Medical Imaging Technology;2005-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Zhi-yong,GE Ying,LIU Jing-hong,WANG Ke-li,WU Jian-lin(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China);Preliminary clinical evaluation of CT perfusion imaging of stomach neoplasm[J];Journal of Dalian Medical University;2008-04
2 WANG Shuang,ZHAO Xin-ming,LIN Meng,et al.Department of Radiology,Cancer Hospital,Chinese Academy of Medical Sciences,Beijing 100021,P.R.China;CT Perfusion Imaging of Liver:the Role in the Diagnosis of Early Hepatocellular Carcinoma[J];Radiologic Practice;2008-03
3 ZHANG Xiaoling, MENG Quanfei, ZHANG Chaohui, et al. Department of Radiology of the First Hospital, Sun Yat-sen University, Guangzhou 510080, China;Pathological and imaging study of improved VX2 bone tumor model of rabbit[J];Chinese Journal of Bone Tumor and Bone Disease;2007-02
4 Yu-lin LIU,Xian CHEN,Zhao-xi ZHANG,Dong-ping DU,Ning XU,Chun-lin JIANG,Qiong-hua TU Department of Radiology,Hubei Cancer Hospital,Wuhan 430079,China;The Correlation Between MSCT Perfusion Parameters and Clinical Staging in Nasopharyngeal Carcinoma[J];Contemporary Medicine;2009-20
5 Li-dong LIU,Dan-ke SU,Guan-qiao JIN,Meng-ou ZHAO,Qiang LI,Wei-li HUANG Centre of Imaging Diagnosis,Affiliated Tumor Hospital,Guangxi Medical University,Nanning 530021,China;Study on Diagnostic Value of Multi-slice Spiral CT Perfusion in Recurrent Nasopharyngeal Squamous Cell Carcinoma[J];Contemporary Medicine;2009-20
6 MA Zhi-wen,DONG Dan-dan,HAN Xue(Department of CT Room,The First Clinical College,Harbin Medical University,Harbin 150001,China);Diagnosis and classification of astrocytic tumors by multi-slice CT perfusion imaging[J];Journal of Harbin Medical University;2007-02
7 ZHOU Jun,LONG Qingyun,LIU Junfang,et al.Department of Radiology,Zhongnan Hospital of Wuhan University Wuhan,HuBei Province 430071,P.R China;Establishment of Rabbit Model Bearing Uterus VX2 Tumor and its Imaging Manifestations[J];Journal of Clinical Radiology;2009-03
8 LU Na, GUO Qi-yong, CHEN Li-ying (Department of Radiology, the Second Affiliated Hospital of China Medical University, Shenyang 110004, China);CT perfusion imaging of pancreas[J];Journal of China Clinic Medical Imaging;2006-12
9 LU Na1, REN Ying1, GUO Qi-yong1, LI Hai-wei2, CHEN Li-ying1 (1. Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China; 2. Department of Radiology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China);Study of CT perfusion in normal kidneys[J];Journal of China Clinic Medical Imaging;2007-03
10 BI Chun-long,GUO Qi-yong(Department of Radiology,Shengjing Hospital of China Medical University,Shenyang 110004,China);Clinical application of perfusion imaging with multi-slice spiral CT in the diagnosis of pancreatic diseases[J];Journal of China Clinic Medical Imaging;2007-12
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 JIANG Chang-Bin1,2,3, LIU Xiu-Fang1,2, HE Yu-Xiang1,2, NIU Dao-Li3, XIA Yun-Fei1,2 1. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China 2. Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China 3. Department of Radiation Oncology, The First Affiliated Hospital, Guangzhou Medial College, Guangzhou, Guangdong, 510230, P. R. China;Effect of DNA-PKcs Antisense Oligodeoxynucleotides on Radiosensitivity of Nasopharyngeal Carcinoma Cell Lines with Different p53 Function Statuses[J];Chinese Journal of Cancer;2008-02
2 ZHENG Yan-bo, XU Ke. Department of Radiology, First Hospital, China Medical University, Shenyang 110001, China;Expression and clinical significance of hypoxia-inducible factor-1 alpha after TACE on rabbit VX2 liver neoplasms[J];Journal of Interventional Radiology;2007-05
3 SUI Jun WU Jinpeng LI Xiaojiang MA Jing CAO Xiaojuan GAO Wei REN Yanxin(Department of Head and Neck Surgery,the Third Affiliated Hospital of Kunming Medical College,Kunming,650118,China);The expression and significance of hypoxia inducible factor-1α and microvessed density in human nasopharyngeal carcinoma[J];Journal of Clinical Otorhinolaryngology Head and Neck Surgery;2008-06
4 ZHANG Jingfeng, WANG Renfa, WANG Min,et al. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University ofScience and Technology, Wuhan, Hubei Province 430030, P. R. China;Comparative Study of Multi-slice Spiral CT Perfusion and Pathological Findings in VX2 Soft-tissue Tumors of Rabbits[J];Journal of Clinical Radiololgy;2005-05
5 HUANG Biao, LIANG Changhong, ZHANG Yunting, et al. Department of Radiology, Guangdong Provincial People′s Hospital, Guangzhou,Guangdong Province 510080, P. R. China;Correlation Study Between CT Perfusion and Tumor Microvascular Density in Rabbit VX2 Soft-tissue Tumor[J];Journal of Clinical Radiololgy;2005-08
6 PAN Aizhen, WEI Guangyu, GAN Yi,et al. Department of Radiology, No.1 People's Hospital, Foshan, Guangdong Province 528000, P. R. China;Analysis of CT Perfusion in Nasopharyngeal Cancer, Inflammatory and Scar Structure[J];Journal of Clinical Radiololgy;2005-11
7 ZENG Gong-jun1, LIU Jian-hua1, GAO Yun-hua2, LIU Zheng2, TAN Kai-bin2, WU Mei1 (1. Department of Medical Ultrasound, First Municipal People's Hospital, Guangzhou 510180, China; 2. Department of Ultrasound, Xinqiao Hospital, Chongqing 400037, China);Experimental study on lipid ultrasound contrast agent in imaging and differentiating renal VX2 carcinoma[J];Journal of China Clinic Medical Imaging;2008-06
8 HUANG Biao, LIANG Chang-hong, ZHANG Yun-ting, ZHOU Dong, LIN Hua-huan, RU Guang-teng, LIU Hong-jun, LIU Qi-shun(Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080,China);The Correlative Study Between CT Perfusion Imaging and Microvascular Density of Astrocytoma[J];Journal of Practical Radiology;2005-05
9 JIN Guan-qiao,SU Dan-ke,ZHU Xiao-dong,XIE Dong,HUANG Chen-yang(CT Department,the Affiliated Tumor Hospital of Guangxi Madical University,Nanning 530021,China);The Primary Study of Multi-slice Helical CT Perfusion in Nasopharyngeal Carcinoma[J];Journal of Practical Radiology;2005-10
10 HUANG Guo sen, TU Qing song, WEI Guang yu (Department of Radiotherapy, The First Hospital of Foshan, Guangdong Foshan 528000, China);Neoangiogenesis in nasopharyngeal carcinoma and its clinic significance[J];Chinese Journal of Otorhinolaryngology-skull Base Surgery;2004-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 SHAO Guoliang, ZHOU Kangrong, WANG Jianhua,et al. Department of Radiology, The Affiliated Zhongshan Hospital, Medical College of Fudan University, Shanghai 200032, P.R.China;Improvement in Making Rabbit Model Bearing VX2 Liver Tumor for Interventional Experimental Study and CT Evaluation of the Tumor[J];JOURNAL OF CLINICAL RADILOLGY;2000-10
2 ZHANG Jing, QI Jianpin, CHENG Lang, et al. Department of Radiology, The Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, P. R. China;Evaluation of Tumor Vessel Permeability in Cerebral Neoplasm with Multi-slice Helical CT Perfusion Imaging[J];Journal of Clinical Radiololgy;2004-08
3 LONG Liling, WEI Xinhua, HUANG Zhongkui, et al. Department of Radiology, No.1 Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi Province 530027, P. R. China;Evaluation of Perfusion MR Imaging in Preoperative Grading of Astrocytoma[J];Journal of Clinical Radiololgy;2004-09
4 ZHANG Jingfeng, WANG Renfa, WANG Min,et al. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University ofScience and Technology, Wuhan, Hubei Province 430030, P. R. China;Comparative Study of Multi-slice Spiral CT Perfusion and Pathological Findings in VX2 Soft-tissue Tumors of Rabbits[J];Journal of Clinical Radiololgy;2005-05
5 HUANG Biao, LIANG Changhong, ZHANG Yunting, et al. Department of Radiology, Guangdong Provincial People′s Hospital, Guangzhou,Guangdong Province 510080, P. R. China;Correlation Study Between CT Perfusion and Tumor Microvascular Density in Rabbit VX2 Soft-tissue Tumor[J];Journal of Clinical Radiololgy;2005-08
6 WANG Xiao-dong,REN Jun,YANG Ren-jie,et al.Department of Internal Medicine,Peking University School of Oncology,Beijing 10036,China.;Relationship between the number of VX2 alive cell with the rate and time of liver tumor growth in rabbit.[J];Journal of Modern Oncology;2005-05
7 PU Jun-zhi,ZHI Yan,GE GEN Tuo-ya,GUAN Li-jun,MEI Xiao-fang,LIU Jun(Department of CT,the First Hospital of Huhhot 010020,Innermogolie,China);A Comparative Study Between Pathology and CT Classified Patterns and Diagnosis of the Golioma of the Brain (A Report of 70 Cases)[J];Journal of Practical Radiology;2002-09
8 LIU Yi-yong , WAN Zhi-min ,CAO Wei,GUO Wei-ping,ZHANG Hong-xin,WANG Yi-qing,LI Wen-xian,CHEN Lan,HAN Rui-yang(Department of Intervention ,Tangdu Hospital ,Forth Military Medical University ,Xi'an , Shannxi Province 710038, China);Application of VX_2 Model in Rabbit Thigh to Experiment of Interventional Thermochemotherapy[J];Journal of Practical Radiology;2003-06
9 DU Wei -qing,DENG Jing -lan,HUAN Yi,WANG Jing,GE Ya-li,YANG Chun-min,YANG Yan,CHANG Ying-juan(Department of Radiology,Xijing Hospital, the Fourth Military Medical University, Xi’an 710032,China);Correlative Study of MR Perfusion Weighted Imaging with Histopathologic Grade in Gliomas[J];Journal of Practical Radiology;2004-05
10 XU Hong-wei, CHAO Ming, WANG Bo-lin, WU Jian-jun, SUN Ji-hong(Department of Radiology, Shaoxing Second Hospital, Zhejiang Province,Shaoxing 312000, China);The Study of Hepatic Perfusion Disorders with Multi-Slice Spiral CT[J];Journal of Practical Radiology;2004-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved