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《Shanghai Medical & Pharmaceutical Journal》 2001-11
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Approaching the antisenescence effect of panglycoside extract of Gynostemma pentaphyllum(Thunb) Mak

Ye Hong, Ma Yongxing 1, Xie Shuzhen 1, Gan Jiemin 1 (Dept. of Rehabilitation of Huadong Hospital, Shanghai, 200040; 1Shanghai Institute of Geriatrics, Shanghai, 200040)  
Objective: To investigate the effects of panglycoside extract of Gynostemma pentaphyllum (Thunb.) Mak on the superoxide dismutase (SOD) content of erythrocytes,serum lipoperoxides (LPO) level, natural killer cell activity and memory quotient (MQ). Methods:In a double blind way 51 senescent patients received the drug 60mg tid for 2 months and 40 senescent patients of the control group received placebo.Results:After treatment with the drug, mean SOD content of erythrocytes was significantly increased (P0.01), mean serum LPO level was significantly decreased (P0.01) and MQ was increased(P0.05). However, no significant effects were observed in the patients of control group. Conclusion:Panglycoside extract of Gynostemma pentaphyllum (Thunb.)Mak is beneficial to the senescent patients and will promote their health.
【CateGory Index】: R285.5
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