Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical and Experimental Medicine》 2013-13
Add to Favorite Get Latest Update

The related factors about plasma apelin-13 level,insulin resistance and hypertension of type 2 diabetes mellitus patients

CHEN Shu juan,CHAI Jie,LI Hai-yan. Department of Endocrinology,The Second People's Hospital of Shenzhen,Guangdong Shenzhen 518000,China.  
Objective To study the relationship between the plasma apelin-13 level,insulin resistance and hypertension of type 2 diabetes mellitus patients.Methods Thirty patients with type 2 diabetes mellitus in our hospital during the period from Dec 2011 to Dec 2012 were regarded as the observation I group.Thirty patients with type 2 diabetes mellitus combined with hypertension were regarded as the observation II group.Thirty healthy physical examination people in the same period were regarded as the control group.The levels of plasma apelin-13,fasting plasma glucose(FPG),fasting insulin(FINS),insulin resistance index(IR) and blood pressure were detected,compared and analyzed.Results Compared with the control group,the level of apelin-13 was obviously increased in the observation I group,which was significantly decreased in the observation II group(P 0.05).Compared with the observation I group,the level of apelin-13 was obviously decreased in the observation II group(P 0.05).There were negative relationship between the plasma apelin-13 and FINS,IR and SBP.Conclusion The level of plasma apelin-13 increased significantly in the type 2 diabetes mellitus patients and decreased obviously in the type 2 diabetes mellitus patients combined with hypertension.The level of plasma apelin-13 is negatively correlated with the FINS,IR and SBP.
【Fund】: 2012年深圳科技计划项目 项目名称:Apelin与糖尿病心脑血管疾病相关性的临床研究 项目编号:201202034
【CateGory Index】: R587.1;R544.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 LI Li,LI Rui-Jie,SONG Li-Fen,GENG Ao,and GAO Lei(Department of Cardiology,Chuiyangliu Hospital of Beijing,Beijing 100022,China);Correlation of Plasma Apelin to Left Ventricular Hypertrophy and Carotid Atherosclerosis in Patients with Essential Hypertension[J];Chinese Journal of Arteriosclerosis;2008-07
2 HUANG Zhen-gui,ZHANG Pei,YANG Fan,DING Bo-ping(Wannan Medical College,Wuhu 241002,China);Effects of puerarin on apelin-12,angiotensin II,NO and blood pressure in renovascular hypertensive rat[J];Chinese Journal of Pathophysiology;2011-12
3 ZHENG Tian-Peng,GUO Chang-Hui,ZHOU Ting-Ting,et al.Department of Endocrinology,the Second Affiliated Hospital,Chongqing Medical University,Chongqing 400010,China;The relationship between plasma apelin-12 level and hypertension,insulin resistance of type 2 diabetes mellitus patients[J];Chinese Journal of Gerontology;2010-04
Chinese Journal Full-text Database 4 Hits
1 ZHANG Zhi1,2, and YU Bo1(1.Department of Cardiology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China; 2.Department of Cardiology, the First Affiliated Hospital of Liaoning Medical University, Jinzhou 121001, China);The Effect of Apelin-13 on Ischemia-Induced Cardiomyocyte Apoptosis in Acute Myocardial Ischemia Rats[J];Chinese Journal of Arteriosclerosis;2008-09
2 HUANG Zhen-gui,BAI Song,CHEN Li,WANG Jiang-tao,DING Bo-ping(Department of Pharmacology & Pharmacology of Traditional Chinese Medicine Grade Three Laboratory, State Administration of Traditional Chinese Medicine of China,Wannan Medical College,Wuhu 241002,China);Effect of puerarin combined with felodipine on mRNA and protein expression of apelin and APJ in renovascular hypertensive rat[J];China Journal of Chinese Materia Medica;2013-03
3 WANG Lin1,NIE Jing2,TENG Tian-ming2,LI Hong-shi2,YU Xue-fang2,MA Jun1(1Tianjin Medical University,Tianjin 300070,China;2Tianjin Medical University General Hospital,Tianjin 300052,China);Effects of apelin-13 on transient sodium currents in rat ischemic ventricular myocardial cells[J];Chinese Journal of Pathophysiology;2013-03
4 YANG Mei;YANG Gangyi;WEI Youneng;HE Liping;TENG Xiaochun;Department of Endocrinology,the First People's Hospital of Northern New District;Department of Endocrinology,the Second Affiliated Hospital,Chongqing Medical University;Department of Geronotology,General Hospital of Chongqing Iron and Steel;;Changes in plasma Apelin and Visfatin levels and relevant factors in the population with different glucose tolerance[J];Journal of Chongqing Medical University;2013-09
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 WU Zhe-bing, YU Jing,LI Guang-di, GUO Xue-ya, CHANG Peng, HE Da-yuan Department of Cardiology, the Second Hospital of Lanzhou University, Lanzhou 730030, China;Effect of telmisartan on plasma apelin-12 in patients with essential hypertension[J];Clinical Focus;2006-21
2 YU Yang,HUANG De-jia (Department of Cardiology,West Hosipital,Sichan University,Chengdu,Sichuan 610041,China);Effects of exogenous Apelin on cardiomyocyte hypertrophy[J];Chinese Heart Journal;2006-02
3 BAI Dan-na,GAO Yan,LI Hong-mei,YE Ji-xian,LI Yang,FENG Xiao,LI Wen-bin (Department of Cardiology,PLA 323rd Hospital,Xi'an 710054,Shaanxi,China);Effect of apelin-13 on lowering blood pressure of spontaneously hypertensive rats[J];Chinese Heart Journal;2010-04
4 MEI Cong1,SONG Dian-ping1,YAN Xin-min2.(1.Department of Diabetes,First Affiliated Hospital of Kunming Medical College,Kunming 650031,China;2.Research Institute of Clinical and Preclinical Research,First People's Hospital of Yunan Province,Kunming 650032,China);Study Progress of Adipokine Apelin[J];Medical Recapitulate;2008-01
5 CHEN Xiu-fang1,LEI Kang-fu1,DONG Min2,FANG Zhou-xi2,JIN Li-qin1(1Department of Biochemistry,2Central Laboratory of Biology,Wenzhou Medical College,Wenzhou 325035,China. );Effect of puerarin on myocardial damage in STZ-induced diabetic rats[J];Chinese Journal of Pathophysiology;2010-04
6 JIN Ge1,YANG Penglin1*,GONG Yongsheng2,FAN Xiaofang2,TANG Jifei1,LIN Jiafeng1 (1.Department of Cardiovascular Internal Medicine,Second Affiliated Hospital,Wenzhou Medical College,Wenzhou 325027,China;2.Institute of Cor Pulmonale and Teaching Centre of Functional Experiment,Wenzhou Medical College,Wenzhou 325035,China);Effects of puerarin on expression of apelin and its receptor of 2K1C renal hypertension rats[J];China Journal of Chinese Materia Medica;2009-24
7 WEI Li JIA Wei-ping WU Hai-ya LU Jun-xi BAO Yu-qian LU Hui-juan PAN Xiao-Ping XIANG Kun-san.Department of Endocrinology and Metabolism,Shanghai Institute of Diabetes,Shanghai Sixth People's Hospital Affiliated to Jiaotong University,Shanghai 200233,China;Analysis of serum apelin level and related factors in obese and type 2 diabetic patients[J];Chinese Journal of Endocrinology and Metabolism;2007-02
8 JIN Ge1, YANG Peng-lin1, GONG Yong-sheng2, FAN Xiao-fan2, ZHUANG Hong1(1. Department of Cardiovascular Internal Medicine, the Second Hospital Affiliated to Wenzhou Medical College, Wenzhou 325027, Zhejiang,China;2. Institute of Cor Pulmonale and Teaching Centre of Functional Experiment,Wenzhou Medical College,Wenzhou 325035,Zhejiang,China);Effects of Puerarin on Expression of Apelin/APJ Gene at Left Ventricular of 2K1C Renal Hypertension Rats[J];Chinese Archives of Traditional Chinese Medicine;2008-11
9 WU Wen-hua,ZHANG Ji-ye,WANG Yu,LIANG Ji-chao,HAN Feng-mei,CHEN Yong(Hubei Province Key Laboratory of Biotechnology of Chinese Medicine,Hubei University,Wuhan 430062,China);Effect of Puerarin on the Blood Pressure of Spontaneously Hypertensive Rat[J];Acta Chinese Medicine and Pharmacology;2010-04
10 Zhang Nianbao,Chen Huizhen,Cui Weidong,Ding Boping,Huang Zhenggui (Department of Pharmacology,Wannan Medical College & Pharmacology of TCM Grade Three Laboratory,State Administration of Traditional Chinese Medicine ,Wuhu 241002);Antihypertensive effect of puerarin in renal hypertensive rats and its effect on level of angiotensin II in renal tissue[J];Pharmacology and Clinics of Chinese Materia Medica;2010-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved