Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical and Experimental Medicine》 2013-23
Add to Favorite Get Latest Update

The clinical significance of plasma surfactant protein-D in patients with septic ARDS

ZHI De-yuan;DUAN Mei-li;ZHANG Shu-wen;Intensive Care Unit,Beijing Friendship Hospital,Capital Medical University;  
Objective To investigate the clinical implication of the dynamic change of plasma Surfactant protein-D( SP-D) in septic acute re- spiratory distress syndrome( ARDS) patients. Methods Plasma samples of patients with sepsis at various stages were analyzed prospectively. 40 consec- utive patients from Jan 2012 to Oct 2012 with sepsis were enrolled into this study. The samples were divided into two groups,group of systemic inflamma- tory response syndrome( SIRS)( the control group) and ARDS group according to the criteria of ARDS. Then the ARDS group were divided into 4 sub- groups,the mild,moderate,severe and terminal group according to the Berlin definition of ARDS. The correlations between the plasma samples of SP- D levels of enzyme- linked immunosorbent( ELASA) and patients' clinical features were analyzed. Results The SP- D level was higher in the mild ARDS patients than these in SIRS( 0. 723 ±0. 153 ng / ml vs 0. 510 ±0. 187 ng / ml,P 0. 05). As ARDS became seriously,the levels of plasma SP- D is progressive increase( ARDS mild vs. ARDS moderate: 0. 723 ±0. 153 ng / ml vs 1. 043 ±0. 198 ng / ml,P 0. 05; ARDS moderate vs ARDS severe: 1. 043 ±0. 198 ng / ml vs. 1. 343 ±0. 186 ng / ml,P 0. 05); ARDS moderate vs. ARDS severe: 24. 98 ±1. 65 ng / ml vs. 26. 18 ±2. 83 ng / ml,P 0. 05). The SP- D level was negatively correlated with PaO 2 / FiO 2( r =-0.436,P 0.05),and positively correlated with and AaDO 2,SOFA score and A- PACHEⅡ( r =0. 314,0. 321 and 0. 453,respectively,P 0. 05). Conclusion Level of sepsis patients' plasma SP- D may be helpful in the diagnosis of septic ARDS.
【CateGory Index】: R459.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 LI Jian-zhong;LIU Zhi-guo;CHANG Li-rong;Department of Specical Medicine,306th Hospital of PLA;;Experimental drug intervention study on dinitrogen tetroxide inhalation induced acute pulmonary edema in mice[J];Journal of Clinical and Experimental Medicine;2015-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Xiangde;Pulmonary and Critical Care Medicine,University of Nebraska Medical Center;;Update in the Management of Sepsis and Septic Shock[J];Trauma and Critical Care Medicine;2014-01
2 XIANG Shu-lin;Intensive Care Unit,the People's Hospital of Guangxi Zhuang Autonomous Region;;Detection and Prognosis of Extravascular Lung Water Index in Elderly Patients with Respiratory Failure and Septic Shock[J];Guangxi Medical Journal;2014-01
3 ZHOU Feihu;SONG Qing;Department of Critical Care Medicine,PLA General Hospital;;Effectiveness and Safety of Norepinephrine versus Vasopressin for Septic Shock: A Meta-analysis[J];Trauma and Critical Care Medicine;2013-01
4 MENG Qing-xue;LIU Yu-fen;LIU Jing;WU Di;College of Life Science and Technology,Harbin Normal University;;Research Progress of Pulmonary Surfactant Proteins[J];China Animal Husbandry & Veterinary Medicine;2014-03
5 Li Xingyu;Liu Yanqiu;Chen Hui;Department of Anesthesiology,Affiliated Hospital of Guiyang Medical College;;Influence of low tidal volume combined with low level PEEP on respiratory function of elderly patients in general anesthesia[J];Chongqing Medicine;2014-12
6 LIU Xiangde;Pulmonary and Critical Care Medicine,University of Nebraska Medical Center;;Update in the Management of Intensive Care Medicine[J];Trauma and Critical Care Medicine;2014-02
7 LIN Xing-sheng;SHI Song-jing;Department of Medical Intensive Care Unit, Fujian Provincial Hospital;;Advances of fluids challenge are in the MODS-induced Tissue Hypoperfusion[J];Journal of Trauma and Emergency(Electronic Version);2013-02
8 WANG Jianbin;WANG Hua;CHEN Qikang;CEN Zhongran;TANG Ying;CAI Liang;LIU Zhanguo;CHANG Ping;Department of Critical Care, Zhujiang Hospital, Southern Medical University;Lecong Hospital of Shunde Distinct;;Role of central venous pressure, global end diastolic volume index and extravascular lung water index in evaluating fluid resuscitation in patients with septic shock[J];Journal of Southern Medical University;2014-09
9 Qin Long;Zhang Yingping;Liu Qiumin;Department of ICU,Beijing Haidian Hospital;;Analysis on risk factors associated with gastrointestinal dysfunction syndrome in patients with sepsis[J];Infection,Inflammation,Repair;2013-03
10 CUI Ping;CHENG Bao-li;FANG Xiang-ming;Department of Intensive Care Unit,First Affiliated Hospital,Medical College,Zhejiang University;Department of Anesthesiology,First Affiliated Hospital,Medical College,Zhejiang University;;Biomarkers of sepsis[J];Journal of Traumatic Surgery;2014-06
China Proceedings of conference Full-text Database 1 Hits
1 ZHANG Haipeng;WANG Rui;WANG Hui;ZHANG Wei;JiNan University,Shandong Academy of Medical Sciences, Shandong Academy of Occupational Health and Occupational Medicine;;Dynamic changes of Clara cell protein and Surfactant protein-D expressions in lung tissue and bronchoalveolar lavage fiuid of silica-treated rats[A];[C];2013
【Co-references】
Chinese Journal Full-text Database 8 Hits
1 XIE Haokong(Department of Emergency,Central Hospital of Yongzhou City,Yongzhou 425006,Hunan,China);Changes of Serum SOD,NO and TGF-β_1 Levels in Patients with Lung Injury Caused by Acute Paraquat Poisoning[J];Journal of Guiyang Medical College;2012-04
2 HUANG Yong;ZHENG Qing;Clinical laboratory,Hainan Public Service Center for Improving Birth Outcome and Child Development;;Significance of transforming growth factor- β_1 and Krebs Von den lungen-6 in plasma and bronchoalveolar lavage fluid in children with bronchopulmonary dysplasia premature[J];Guangdong Medical Journal;2014-12
3 QIAO Hong-mei,PANG Huan-xiang,ZHANG Yun-feng,CHENG Huan-ji,LIU Li,LU Ji-rong(Department of Pediatrics,The First Hospital of Jilin University,Changchun 130021,Jilin,China);hanges of IL-6,IL-10 and TNF-α in children with Mycoplasma pneumoniae pneumonia[J];Journal of Clinical Pediatrics;2012-01
4 ZHOU Zhong-hai,LEI Ting,YAN Chun-song.Liaocheng City Hospital of Infectious Disease,Liaocheng 252000,China;Associations of Serum Surfantant Protein D and C-reaction Protein with Clinical Factors in the Stable Phase of Chronic Obstructive Pulmonary Disease[J];Chinese General Practice;2011-22
5 LI Jian-zhong1,LIU Zhi-guo1,ZHANG Rui-hua2,et al.1 Department of Specical Medicine,The 306th Hospital of PLA;2.Fourth Institute of Chemical Defense Academy of PLA,Beijing 100101,China.;Study on pathological changes and blood levels of ANP and MetHb in mice with lung injury induced by inhalation of nitrogen tetroxide[J];Journal of Clinical and Experimental Medicine;2013-03
6 CHAI Wen-shu,LI Ying,ZHANG Hai-lin,MA Xiao-yu(Dept of Respiratory Disease,the First Afiliated Hospital,Liaoning Medical College,Jinzhou Liaoning 121001,China);Effect of breviscapine on TGF-β1 and hyaluronic acid of lung tissue in pulmonary fibrosis rats[J];Chinese Pharmacological Bulletin;2010-12
7 ZHANG Jin-rong,LIU Shan-shan,LV Yin,ZHANG Guoqing,LIU Hao,WANG Fei(Department of Radiotherapy,Affiliated Tumor Hospital,Xinjiang Medical University,Urumqi Xinjiang 830011,China);A study of correlation between TNF-α,IL-6,ACE levels in plasma,dose-volume-histogram parameters and radiation pneumonitis[J];China Oncology;2010-06
8 WU Hong-mei,YU Ying,ZHANG Li,et al.(Department of Pediatrics.Nanjing First Hospital,Nanjing Medical University,Nanjing 210006,China);The clinical value of serum total IgE and serum TNF-α in asthmatic children[J];Chinese Journal of Laboratory Diagnosis;2010-08
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved