Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Applied Clinical Pediatrics》 2007-02
Add to Favorite Get Latest Update

Risk Factors of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants

CHEN You,YE Zhen-zhi,LU Guang-jin(Department of Neonatology,Bao'an Maternal and Child Health Hospital of Shenzhen,Shenzhen 518000,China)  
Objective To investigate the risk factors,prevention and treatment of bronchopulmonary dysplasia(BPD) in very low birth weight infants(VLBWI).Methods A retrospective study was performed in VLBWI with mechanical ventilation and hospitalized more than 28 days.More than 20 factors were analyzed as the risk factors of BPD.Results The overall incidence of BPD in VLBWI with mechanical ventilation and hospitalized more than 28 days was 41.07%(23/56),and 17.04%(23/135)in those VLBWI who received mechanical ventilation,and 6.20%(23/371) in those infants whose birth weight ≤1 500 g.FiO_2,peak inspiratory pressure(PIP),positive end-expiratory pressure(PEEP),mean airway pressure(MAP),the days of starting mechanical ventilation,maternal prenatal administration of dexamethasone and usa -ge of pulmonary surfactant to newborn had no significant differences between BPD and control groups(P_a0.05).But there were significant differences in gestational age less than or equal to 30 weeks,birth weight less than 1 250 g,times of mechanical ventilation treatment (≥2 times),pulmonary infection,pneumorrhagia,prolonged mechanical ventilation(≥5 days) and positive culture of the lower respiration secretion more than 2 times(P_a0.05);Multivariate logistic analysis revealed that pulmonary infection with regression coefficient 0.952,odd ratio(OR)2.591;the days prolonged mechanical ventilation with regression coefficient 0.144,OR 1.154.Conclusion Shortening the duration of mechanical ventilation to prevent pneumonia,particularly serious pnenumonia,is important in preventing BPD.
【CateGory Index】: R722
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 WU Hai-lan,LIU Hong,JIN Fei,QI Yu-jie,LI Geng,WENG Jing-wen(Neonatal Intensive Care Unite,Beijing Children's Hospital Affiliated to Capital Medical University,Beijing 100045,China);Clinical Analysis of Bronchopulmonary Dysplasia in 25 Premature Infants[J];Journal of Applied Clinical Pediatrics;2009-14
Chinese Journal Full-text Database 5 Hits
1 ;Progress in Bronchopulmonary Dysplasia[J];Foreign Medical Sciences Section of Pediatric;2005-04
2 Song Jinzhi, Wu Benqing, Pan Xiaomei, Liu Zhi- ping.Department of Newborn Infants, Second Hospital Affiliated to Jinan Medical University Shengzheu, Guangdong 518020;Analysis of the multiple factors related to the outcomes of the mechanical ventilation therapy for neonatal hyaline membrane disease[J];The Journal of clinical Pediatrics;2004-06
3 WU Ling.Nanjing Children′s Hospital,Nanjing University of Medical Science,Nanjiang 210008,China;The affecting factors of neonatal hyaline membrane disease complicated bronchopulmonary dysplasia[J];Pediatric Emergency Medicine;2004-05
4 RONG Zhi - hui, CHANG Li - wen , QIAN Li - ling,LI Wen - bin (Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 , China);Expression Level of Matrix Metalloproteinases, Tissue Inhibitor of Metalloproteinases and Activity of Nuclear Factor Kappa B in Different Phases of Bronchopulmonary Dysplasia[J];Journal of Applied Clinical Pediatrics;2005-05
5 Liu Meina,Zhuang Siqi,Qin Zhaoyuan,et al.The First Affiliated Hospital of Sun Yet-sen University,Guangzhou 510080,China;The risk factors for bronchopulmonary dysplasia in premature.[J];Chinese Journal of Practical Pediatrics;2005-07
Chinese Journal Full-text Database 10 Hits
1 KONG Xiang-Yong, DU Jiang, FENG Zhi-Chun. Department of Pediatrics, Zhujiang Hospital, Nanfang Medical University, Guangzhou 510282, China;Temporal expression of thyroid transcription factor-1 in fetal and neonatal human lungs[J];Chinese Journal of Contemporary Pediatrics;2006-01
2 CHEN You, HAN Yu-Kun, YE Zhen-Zhi, LU Guang-Jin. Department of Neonatology, Baoan Maternal and Child Health Hospital, Shenzhen, Guangdong, China;Risk factors for bronchopulmonary dysplasia in neonates with respiratory distress syndrome[J];Chinese Journal of Contemporary Pediatrics;2007-01
3 ZHANG Xiao-Ting,LIU Jian,YU Xiao,NING Qin,LUO Xiao-Ping.Department of Pediatrics,Tongji Hospital,Tongji Midical College,Huazhong Uninversity of Science and Technology,Wuhan 430030,China;Lipopolysaccharide and hyperoxia induce nuclear factor-kappa B expression in human embryo lung fibroblasts in vitro[J];Chinese Journal of Contemporary Pediatrics;2008-05
4 BAO Lei, YU Jia-lin (Children's Hospital, Chongqing University of Medical Sciences, Chongqing 400014, China);Analysis of the results of sputum culture and clinical characteristic of the mechanical ventilation for neonatal respiratory distress syndrome[J];Journal of Pediatric Pharmacy;2006-01
5 GAN Xin lian,ZHANG Jian hua,PAN Chu,et al.Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,P.R.China;The imaging appearances of bronchoplumonary dysplasia of newborn(with report of 21 cases)[J];Radiologic Practice;2003-12
6 Gao Xiaoling,Hao Liting,Li Jianqiang,Liu Zhuola﹡(Department of Respiratory Disease,The Second Hospital of Shanxi Medical College,Taiyuan 030001,China);INFLUENCE OF BILIRUBIN ON THE EXPRESSIONS OF PDGF-B AND IGF-I IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE[J];Chinese Journal of Histochemistry and Cytochemistry;2009-02
7 YI Chun-hui,ZHU Ping-zhao (Changning People's Hospital,Changning,Hunan 421500,China);Risk Factors of Bronchopulmonary Dysplasia in Premature Infants[J];Journal of Nanhua University(Medical Edition);2008-03
8 Zhang Yaping,Zhang Hao,Shao Xiaomei.Children's Hospital,Fudan University,Shanghai200032;Follow-up of pulmonary function after mechanical ventilation in neonate[J];The Journal of clinical Pediatrics;2004-04
9 WANG Hua, CHANG Li-wen, LI Wen-bin, CHEN Hong-bing. Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Wuhan 430030, China;Role of hyperoxia on the expression of focal adhesion kinase in lung tissues of premature rat[J];The Journal of Clinical Pediatrics;2006-04
10 RONG Zhi-hui,LI Wen-bin,ZHANG Qian-shen,CHANG Li-wen(Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei,China);Prediction of chronic lung disease with the biochemical markers in lung lavage fluid obtained from ventilated neonates[J];Journal of Clinical Pediatrics;2007-03
Chinese Journal Full-text Database 4 Hits
1 GENG Linlin1),DU Jiang1),FENG Zhichun2) 1) Department of Pediatrics,Zhujiang Hospital,Southern Medical University,Guangzhou 510280 2) Institute of Pediatrics,Beijing Command Hospital of the PLA,Beijing 100700;Expression of TGF-β_1 in lung tissue of new-born rabbits with bronchopulmonary dysplasia[J];Journal of Zhengzhou University(Medical Sciences);2008-03
2 CHANG Li-wen(Department of Pediatrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei,China);Recent advances in diagnosis and management of newborn infants with bronchopulmonary dysplasia[J];Journal of Clinical Pediatrics;2007-03
3 HUANG Mei(Department of Neonatology,Hunan Province Children's Hospital,Changsha 410007,China);Study Progress of Corticosteroids for Treatment and Prevention of Bronchopulmonary Displasia in Preterm Infants[J];Journal of Applied Clinical Pediatrics;2008-02
4 LIU Hong, LI Kehua, CUI Yutao, et al. NICU of Beijing Children's Hospital Affiliated of Capital University of Medical Sciences, Beijing 100045,China;Early Diagnosis and Treatment of Bronchopulmonary Dysplasia in Premature[J];Chinese Journal of Perinatal Medicine;2001-02
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Li-Ling QIAN, Li-Wen CHANG, Qian-Shen ZHANG, Zhi-Hui RONG Department of Pediatrics , Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.;Lung Injury of Preterm Rats Induced by Prolonged Exposure to High Oxygen Concentration of 85%[J];Chinese Journal of Contemporary Pediatrics;2003-02
2 XIAO Zhihui, SUN Bin, ZHAN XiaobinDepartment of Neonatology, Children's Hospital Affiliated of Suzhou University, Suzhou 215003, P.R.China;High frequency oscillatory ventilation in treatment of hyaline membrane diseases[J];Journal of Applied Clinical Pediatrics;2001-05
3 QIAN Liling, CHANG Liwen , RONG Zhihui ,et al.Pediatric Department,Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430030, P. R. China;The therapeutic effect of retinoic acid on the expression of metalloproteinase and metalloproteinase in hyperoxic inhibition of lung development in newborn rats[J];Journal of Applied Clinical Pediatrics;2002-06
4 WAN Weilin, WANG Danhua, ZHAO Shimin, et al. Department of Pediatrics, Peking Union University Hospital, Beijing 100730, China;A retrospective analysis of the effect of antenatal corticosteroids administration on the incidence of HMD in preterm neonates[J];Chinexe Journal of Pediatrics;2000-03
5 LUO Xianqiong. Guangdong Provincial Hospital for Maternal and Children Health, Gougzhou, 510010;The Application of Pulmonary Surfactant and Prognosis of Hyaline Membrane Disease[J];CHINESE JOURNAL OF PERINATAL MEDICINE;1999-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved