Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Applied Clinical Pediatrics》 2008-10
Add to Favorite Get Latest Update

Drug Sensitive Analysis of 207 Strains of Staphylococcus Aureus in Children

XU Min,ZHANG Jian-hua,WU Liang-xia,WANG Zi-cai (Department of Pediatrics,the Sixth People′s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China)  
Objective To analyze the changes of the frequency of staphylococcus aureus (SAU) and methicillin resistant staphylococcus aureus (MRSA) isolated from hospitalized children from 2003 to 2006,and investigate the 21 antimicrobial susceptibility against SAU strains for providing reference for clinical rational use of drug.Methods The SAU strains were isolated from 207 children who were hospitalized in department of pediatrics of the sixth people′s hospital affiliated to Shanghai jiaotong university from Jan.2003 to Dec.2006 during the first 48 h of hospital stay.Strains were isolated from cotton-tipped swab of throat culture 75 strains,sputum culture 57 strains,secretion of bellybutton culture 25 strains,liquor puris culture 23 strains,hemoculture 20 strains,tube thoracostomy culture 3 strains,middle piece urnary culture 3 strains,cerebrospinal fluid culture 1 strain.The strains were identified by latex agglutination test,the in vitro activities of the 21 antimicrobial agents against 207 SAU isolates was tested by disc diffusion test (K-B method) according to the guidelines of the clinical and laboratory standards institute.MRSA was screened by oxacillin disc diffusion test.The data were analyzed by WHONET 5 software,Cochran-Mantel-Haenszel was used to analyze the tendency of SAU isolating rate and MRSA detectable rate.Results Of these SAU,30 strains(14.5 %) isolates were MRSA and 177 strains(85.5 %) were methicillin sensitive staphylococcus aureus.The sensitive rates of SAU to Penicilin,Oxacillin,Cefuroxime Sodium,Cefotaxime,Ceftriaxone,Erythromycin,Clindamycin,Trimethoprim/Sulfamethoxazole,Ciprofloxacin,Fosfomycin and Rifampin were 4.8%,85.5%,84.9%,90.0%,88.3%,37.5%,46.3%,92.7%,74.2%,97.2%,94.0%,respectively.All the strains were sensitive to peptide antibiotic(for instance,vacomycin and teicoplanin) and Levofloxacin.The SAU isolated rate and MRSA detectable rate were 9.6%,19.8%,25.0%,39.5% and 5.0%,5.9%,12.7%,24.7% in 2003-2006,respectively.Conclusions SAU has strong resis-tance to Penicilin and Erythromycin,but relative sensitive to Oxacillin and Cephalosporin.The SAU isolatating rate and MRSA resistant rate is increased in our area,pediatrics should to strengthen the monitoring of SAU is important in pediatrics.
【CateGory Index】: R725.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 WANG Qun 1,YANG Yong-hong 2,GENG Wen-jing 2,WU De-jing 2,YUAN Lin 2,YU Sang-jie 2,SHEN Xu-zhuang 2 (1.Department of Pediatrics,the Affiliated Hospital of Guilin Medical College,Guilin 541001,Guangxi Zhuang Autonomous Region,China;2.Laboratory of Microbiology and Immunology,Beijing Children′s Hospital Affiliated to Capital Medical University,Beijing 100045,China);Clinical Characteristics and Antibiotic Resistance of Staphylococcus Aureus from Skin and Soft Tissue Infections in Children[J];Journal of Applied Clinical Pediatrics;2009-22
2 ZENG Li,ZHANG Fu-shan,FENG Xian-ju(Department of Clinical Laboratory,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China);Drug resistance analysis of methicillin resistant S.aureus[J];Journal of Xinxiang Medical College;2009-02
3 DONG Wei-hua,WANG Tian-yun,WANG Fang(Department of Biochemistry and Molecular Biology,Xinxiang Medical College,Xinxiang 453003,China);Antibacterial function of seleniferous lycium barbarum on staphylococcus aureu and escherichia coli[J];Journal of Xinxiang Medical College;2009-03
Chinese Journal Full-text Database 5 Hits
1 LI Yuqiang,GAO Keyi(The First People’s Hospital of Pingdingshan,Pingdingshan 467000,China);Analysis on Drug Resistance of Meticillin-Resistant Staphylococcus from 1999~2005[J];China Pharmacy;2006-17
2 FANJianfeng ,YANG Yonghong ,TONGYuejuan .DepartmentofMicrobiology,InstituteofPediatrics,BeijingChildren′sHospital AffiliatedtoCapitalUniversityofMedicalSciences,Beijing 10 0 0 45 ,China;Methicillin-resistant Staphylococcus aureus in Beijing children′s hospital,1993-1998[J];Chinexe Journal of Pediatrics;2000-07
3 HUA Chun-zhen~*,LI Jian-ping,YU Hui-min,LI Shan,YE Huan,SHANG Shi-qiang.~*Department of Pediatrics,the Hospital Affiliated to Medical School of Hangzhou Teachers College,Hangzhou NO.2 Hospital,Hangzhou 310015,China;Drug-resistance of staphylococcus aureus and detection of mecA gene in all strains isolated from children in Hangzhou[J];Chinese Journal of Pediatrics;2006-05
4 WANG Hui, SUN Hong-li, CHEN Min-jun,HU Bi-jie, YU Yun-song, SUN Zi-yong, CHU Yun-zhuo, Xu Ying-chun, Xie Xiu-li. Department of Clinic Laboratory,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China;Antimicrobial resistance surveillance of gram-positive cocci isolated from 5 teaching hospitals in China in 2005[J];Chinese Journal of Laboratory Medicine;2006-10
5 MA Yue, LI Jing-yun, YAO Lei, ZHANG Li, HU Chang-qin, JIN Shao-hong. National Center for Surveillance of Antimicrobial Resistance, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China;Antimicrobial resistance of Staphylococcus aureus isolates from inpatients of departments of internal medicine, surgery, and pediatrics and intensive care unit[J];National Medical Journal of China;2003-05
Chinese Journal Full-text Database 10 Hits
1 Huang Jianxiang Yu Conggao Lin Weizhen the First Affiliated Hospital, Guangzhou university of Chinese Medicine, Guangzhou 510405, Chian;The assay of staphylococcus for infection and their antimicrobial resistance[J];Qilu Journal of Medicall Aboratory Sciences;2003-02
2 LI Hong-yu,HUANG Shao-ying,WU Xi-quan.(The Second Affiliated Hospital of Zhongshan University,Guangzhou 510120,Guangdong,P.R.China);Distribution and drug resistance of Enterococcus Faecom in hospital infections.[J];China Tropical Medicine;2008-11
3 GENG Sui-na,ZHOU Xiao-hong,WANG Qian,CHAI Zhi-xin,ZHANG Jie,RUI Yong-yu(Department of Laboratory Medicine,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China);Distribution and Drug Resistance Spectrum of 3144 Bacteria and Candida Clinical Isolates[J];Journal of Tropical Medicine;2007-06
4 Dong Fang, Zhen Jinghui, Zhang Meihe(Department of Examination, Beijing Children's Hospital, Capital University of Medical Sciences);Surveillance of Drug Resistance and Epidemic Distribution of the Clinically-isolated Bacteria in Intensive Care Unit of Beijing Children's Hospital[J];Journal of Capital University of Medical Sciences;2005-03
5 ;临床治疗感染性心内膜炎1例报道[J];Chinese Journal of Practical Internal Medicine;2008-12
6 LU Wei-dong,ZHANG Bin,QU Na,ZHANG Shu-hua,ZHANG Yi-qin(Dept.of Geratology,Tenth People's Hospital,Tongji University,Shanghai 200072,China);Pathogen spectrum and drug resistance of hospital acquired pneumonia in senile patients[J];Journal of Tongji University(Medical Science);2008-03
7 ZHANG Zhi-jun,LIU Guan-xian.Huizhou Municipal CentralHospital, Huizhou ,Guangdong 516001,China.;Epidemiologic study of MRSA nosocomial infections.[J];Proceeding of Clinical Medicine;2009-23
8 LU Xiafei1,LI Jianping2,HUA Chunzhen3,YAN Jie4 (1.Faculty of Laboratory Medicine, Zhejiang Medicine College, Zhejiang Hangzhou 310053,China; 2. the Affiliated Children Hospital of Zhejiang University, Zhejiang Hangzhou 310006, China; 3. Department of Pediatrics, Teacher Training College of Hangzhou, Zhejiang Hangzhou 310012, China; 4. Department of Medical Microbiology and Parasitology, College of Medical Science, Zhejiang University, Zhejiang Hangzhou 310031, China);;Drug Resistance Analysis of 89 Strains of Staphylococcus aureus Isolated from Sputum Specimens of 4 238 Children with Lower Respiratory Tract Infection[J];Journal of Microbiology;2004-05
9 HAO Han-sheng,HAO Su-yun,LIU Min,et al;Surveillance of bacterial resistance of isolates in 2006 and 2007 in our hospital[J];Acta Academiae Medicinae CPAF;2009-07
10 LI Xing-jun1,2,LI Yan1,LIU Ming3,SHI Li3(1.Renmin Hospital of Wuhan University,Wuhan Hubei 430064;2.Affiliated Hospital of Xiangfan Vocational and Technical College,Xiangfan Hubei 441021,China);Retrospective Study on Multidrug-Resistant Bacteria in Hospitalized Patients[J];Journal of Xiangfan Vocational and Technical College;2008-02
Chinese Journal Full-text Database 10 Hits
1 Wang Ling1,Shen Xuzhuang1,Lu Quan2,Wang Yi5,Zeng Qiyi3,Chen Yuan4,Wan Chuanqing5,Deng Qiulian3,Liu Lan4,Zhen Jinghui1,Zhang Hong2,Yang Yonghong1(1.Beijing Children's Hospital,Capital Medical University;2.Shanghai Children's Hospital,Affiliated to Jiaotong University;3.Guangzhou Children's Hospital;4.Children's Hospital of Chongqing Medical University;5.Children's Hospital of Fudan University);Susceptibility Surveillance of Gram-positive Bacteria to Antibiotics Among Children in China:A Study in Beijing,Shanghai,Guangzhou and Chongqing during the Period of 2000-2006[J];Journal of Capital Medical University;2008-05
2 HE Su-yu1,LIU Jing2,NIU Hui-jun3;Ventilator Associated Pneumonia in 35 Premature Infants[J];Journal of Applied Clinical Pediatrics;2008-13
3 XU Fa-lin1,LI Wen-li1,FENG Zhong-jing2,XING Qiu-jing1,CHENG Xiu-yong1 (1.Department of Neonatology,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China;2.Department of Pediatrics,Maternity and Children′s Hospital of Wolong in Nanyang,Nanyang 473000,Henan Province,China);Distribution and Variation of Pathogens in Premature Infants Infected with Bacteria during 10 Years[J];Journal of Applied Clinical Pediatrics;2008-14
4 DENG Yi,OU Wei-lin,ZHANG Hua,TAN Yuan;Analysis of Bacteria Etiology of Neonates with Ventilator-Associated Pneumonia[J];Journal of Applied Clinical Pediatrics;2008-16
5 DONG Wei-hua,ZHAO Chang-an,ZAN Yu-xi(Department of Biochemistry and Molecular Biology,Xinxiang Medical College,Xinxiang 453003,China);Influence of microelement selenium on the antioxidant system of lycium barbarum[J];Journal of Xinxiang Medical College;2007-04
6 DONG Wei-hua,ZAN Yu-xi,ZHAO Chang-an,et al(Department of Biochemistry and Molecular Biology,Xinxiang Medical College,Xinxiang 453003,China);Effects of trace element selenium on the accumulation of nutrient substance and antireversion force of lycium barbarum l.seedlings[J];Journal of Xinxiang Medical College;2008-02
7 Li Shan,Hua Chunzhen,Xu Liqun.Department of Pediatrics,Hangzhou No.2 People's Hospital,Hospital Affiliated to Hangzhou Normal University;Zhejiang 310015,China;Study on Drug-resistance of Staphylococcus Aureus Isolated from Children in Hangzhou[J];Journal of Medical Research;2007-12
8 GAO Wei, BAI Xiang jun ( Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China );The Bacteriology and Drug Sensitivity Analyses of 50 Outpatients with Skin and Soft Tissue Infection[J];Herald of Medicine;2002-04
9 HU Long-hua,XIONG Jian-qiu,JIA Kun-ru,HU Xiao-yan,FENG Wei,GUI Bing-dong(The Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)LUO Qing(School of Public Health,Medical College of Nanchang University,Nanchang 330006,China);In Vitro Antimicrobial Activity of Fusidic Acid Against Methicillin-resistant Staphylococci[J];China Pharmacy;2008-32
10 SUN Hong-li, WANG Hui, CHEN Min-jun. Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China;Antibiotic resistance and molecular epidemiology profile of methicillin-resistant Staphylococcus aureus[J];Chinese Journal of Microbiology and Immunology;2005-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 FANJianfeng ,YANG Yonghong ,TONGYuejuan .DepartmentofMicrobiology,InstituteofPediatrics,BeijingChildren′sHospital AffiliatedtoCapitalUniversityofMedicalSciences,Beijing 10 0 0 45 ,China;Methicillin-resistant Staphylococcus aureus in Beijing children′s hospital,1993-1998[J];Chinexe Journal of Pediatrics;2000-07
2 HUA Chun zhen, SHANG Shi qiang, SUN Xiao feng, LI Jian ping, CHEN Zhi min, YU Xi lin. Department of Central Laboratory, Children′s Hospital Affiliated to Medical College, Zhejiang University, Hangzhou 310003, China;Antibiotics-resistance pattern and genetic type of Streptococcus pneumoniae isolated from children in Hangzhou[J];Chinese Journal of Pediatrics;2004-01
3 WANG Hui *,YU Yun song,LIU Yong,LI Hua yin,HU Bi jie,SUN Zi yong,CHEN Min jun. *Bacteriological Laboratory, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730, China;Resistance surveillance of common community respiratory pathogens isolated in China,2002-2003[J];Chinese Journal of Tuberculosis and Respiratory Diseases;2004-03
4 LIU You-ning~*,CHEN Min-jun,ZHAO Tie-mei,WANG Hui,WANG Rui,LIU Qing-feng,CAI Bai-qiang,CAO Bin,SUN Tie-ying,HU Yun-jian,XIU Qing-yu,ZHOU Xin,DING Xing,YANG Lan,ZHUO Jian-sheng,TANG Ying-chun,ZHANG Kou-xing,LIANG De-rong,L Xiao-ju,LI Sheng-qi,LIU Yong,YU Yun-song,WEI Ze-qing,YING Ke-jing,ZHAO Feng,CHEN Ping,HOU Xiao-na.~*Department of Respiratory Medicine,General Hospital of PLA,Beijing 100853,China;A multicentre study on the pathogenic agents in 665 adult patients with community-acquired pneumonia in cities of China[J];Chinese Journal of Tuberculosis and Respiratory Diseases;2006-01
5 MA Yue, CHEN Hongbo, YAO Lei, LI Jingyun, ZHANG Li, HU Changqin, JIN Shaohong. Division of Antibiotics, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China;The change in sensitivity of methicillin-resistant Staphylococcus aureus to vancomycin[J];Chinese Journal of Internal Medicine;2002-01
6 ZHANG Rui-feng *,XU Zhi-jiang. *Department of Respiratory Diseases,Hangzhou 1st People′s Hospital,Hangzhou 310006,China;Analysis of clinical characteristics and antibiotics resistance of community-acquired MRSA[J];Chinese Journal of Microbiology and Immunology;2004-07
7 HUA Chun-zhen, SHANG Shi-qiang, LI Jian-ping, XU Shan, ZHU Qin. Children′s Hospital of Medical School, Zhejiang University, Hangzhou 310003, China;Phenotype and genetic characterization of capsulated mucoid Streptococcus pneumoniae isolated from children[J];Chinese Journal of Microbiology and Immunology;2004-12
8 LI Jia tai, QI Hui min, LI Yun Behalf of China Bacterial Resistance Surveillance Study Group Institute of Clinical Pharmacology, Peking University, Beijing 100083, China;2002—2003 Bacterial resistance surveillance on Gram-positive cocci isolated from hospital acquired infections and community acquired infections in China[J];Chinese Journal of Laboratory Medicine;2005-03
9 MA Cong, HAO Xiu-hong, JIANG Xue-bing, HAN Shan-qiao, QI Yong-zhi(Department of Microbiology, Navy General Hospital, Beijing 100037, China);Clinical Antibiotic Resistance of 2170 Strains of Gram-positive Cocci[J];Chinese Journal of Nosoconmiology;2005-07
10 Li Shengli Zhang Yingyuan Wu Jufang Zhou Le Wang FuInstitute of Antibiotics Huashan Hospital Shanghai Medical University Shanghai 200040;A survey of nosocomial infection caused by Staphylococcus[J];CHINESE JOURNAL OF NOSOCONMIOLOGY;1998-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved