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《Journal of Applied Clinical Pediatrics》 2009-14
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Clinical Analysis of Bronchopulmonary Dysplasia in 25 Premature Infants

WU Hai-lan,LIU Hong,JIN Fei,QI Yu-jie,LI Geng,WENG Jing-wen(Neonatal Intensive Care Unite,Beijing Children's Hospital Affiliated to Capital Medical University,Beijing 100045,China)  
Objective To explore the risk factors,early diagnosis and treatment of bronchopulmonary dysplasia(BPD)in premature infants.Methods A retrospective study was performed on 25 cases to observe the onset,complications,diagnosis and treatment of BPD.The enrolled patients were hospitalized in NICU from Sep.2003 to Dec.2007 and the follow-up was done for 12 months after their discharge.The key factors of BPD were analyzed and the results of early diagnosis and treatment were observed.Results The number of the 25 patients with gestational age of 26-27 weeks,28-30 weeks,31-32 weeks,35 weeks was 2,17,5 and 1,respectively.The number of their birth weight of 700-1 000 g,1 001-1 500 g,1 501-2 000 g was 9,12 and 4,respectively.Fifteen infants had infection before BPD.Ten infants had patent ductus arteriosus.The earliest clinical diagnosis was made 13 days after birth.Twenty patients were treated by Dexamethasone.Twenty-four infants recovered after treatment and got discharged,but only 1 infant died after withdrawal.Conclusions Premature infants,very low birth weight infants,complicated infection,mechanical ventilation,patent ductus arteriosus etc are the key factors in developing BPD.Crucial actions for preventing and treating BPD include close monitoring on infants susceptive to infection,early diagnosis,infection prevention,closing ductus,early application of diuretics and Dexamethasone.
【CateGory Index】: R722.6
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