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《Chinese Journal of General Practice》 2011-02
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Clinical Analysis of Morphological Changes in Peripheral Blood Cells of Patients with Diabetic Nephropathy

ZENG Bin,ZHENG Hui-feng,LIN Yi-li,et al.Department of Urology,the Second People's Hospital of Shantou,Shantou 515011,Guangdong,China  
Objective To analyze the morphological changes in peripheral blood cells of patients with diabetic nephropathy(DN).Methods HCT,MCV,MCH,MCHC,RDW-SD,MPV,PDW-SD,serum chemical data,urinary albumin excretion rate(UAER),blood pressure and body mass index(BMI) were examined in 88 patients with early stage type 2 diabetic nephropathy(DN) and 30 normal controls.Results The fasting blood glucose,triglyceride(TG),BMI,UAER and systolic blood pressure(SBP) in the DN group were higher than those in the control group(P0.01).The serum albumin was lower in the DN group as compared to the control(P0.01).Conclusion The blood cell shapes of the early stage DN cases had a significant change(P≤0.01).UAER was related to the blood cell shape and SBP.SBP was correlated with the blood cell form,BMI and TG(P0.01).
【Fund】: 广东省汕头市重点科技计划项目(汕府科[2006]82号)
【CateGory Index】: R587.2
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