Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Shenyang Sport University》 2011-01
Add to Favorite Get Latest Update

Effect of Overtraining on Free Radical Metabolism and Activity of PKB in Rat Skeletal Muscle

LI Linyan (P.E.Department,Jingdezhen Ceramic Institute,Jingdezhen 333001,Jiangxi,China)  
Objective:to investigate the mechanism of overtraining and observe the influence to p38 MAPK on free radical Metabolism of skeletal muscle caused by overtraining for six weeks.Methods:thirty male SD rats were randomly divided into control group without training and overtraining group.The rats in the overtraining groups took incremental over training for 6 weeks;Fatigue was evaluated by overall functional status and conventional biochemical indicators.In the further determination,the MDA,SOD,total antioxidant capacity and the protein expression of p38 were determined.Results:serum cortisol,Testosterone/Corticosterone,Hb of the rats in overtraining group decreased significantly(P0.01),BUN increased significantly(P0.01).Serum cortisol,Testosterone/Corticosterone,Hb in overtraining group is decreased by 71.81%,85.21% and 23.12% respectively.Corticosterone in overtraining group is 94.79% higher than that in the control group.They overtook reference standard for diagnosis of human over-training for 30%,30%,20%,20%.Each MDA in skeletal muscle increased significantly(P0.01),SOD and simultaneously total antioxidant capacity in skeletal muscle decreased significantly(P0.05),simultaneously.Muscle glycogen content did not change significantly,glucose decreased significantly,and the protein expression of p38 increased significantly(P0.01).Conclusion:large amount of energy consumption in skeletal muscle,the increasing of radical generation,the reduced antioxidant capacity,excess radical caused by overtraining activated MAPK,but didn't increase the content of muscle glycogen.It is speculated that MAPK regulates skeletal muscle metabolic may be inhibited by the low glucose.
【CateGory Index】: G804.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
2 ShiQingde ,ZhangYong ,WenLi,ChenJiaqi,etal TianjinResearchInstituteofSportsMedicine,Tianjin 3 0 0 3 81;Study on Molecular Mechanism of Mitochondrial Membrane for Exercise-induced Fatigue .Ⅱ. Explores to Pathway of Oxygen Free Radicals Metabolism Induced by Exercise[J];CHINESE JOURANAL OF SPORTS MEDICINE;2000-01
3 Zhu Quan,Pu Junzong,Zhang MinSports Medicine Institute,Beijing Medical University,Beijing,China(100083)Department of Pathological Physiology,Beijing Medical University Beijing,China;A Model for Simulating Overtraining in Rats by Swimming[J];CHINESE JOURANAL OF SPORTS MEDICINE;1998-02
Chinese Journal Full-text Database 10 Hits
1 ZHAO Jiexiu, TIAN Ye , CAO Jianmin, JIN Li (Beijing University of Physical Education, Beijing 100084, China);Development of Researches on Sports Anemia Model in Rats[J];Journal of Beijing University of Physical Education;2003-04
2 ZENG Xi-yin,XU Zhi-fang(Ningxia University,Yinchuan 750021,Ningxia China);A Study on Astragalus Mongholicus Bunge Enhancing the Ability of Anti-Free Radical in Intermittent Training Rats'Myocardium Tissue[J];Journal of Beijing Sport University;2008-06
3 SUN Hong-mei(Department of Basic Theory,Shandong Institute of Physical Education,Rizhao,Rizhao 276826,Shandong China);The Influence of Different Workloads on Rat s' Myocardial Microstructure and Nitric Oxide and Nitric Oxide Synthesis enzyme[J];Journal of Beijing Sport University;2008-07
4 ZHAO Bing1,2,WANG Qing-zhi3,WEN Xiao-jun3,WANG Li-dong2,ZHANG Xi1(1.Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan China;2.Laboratory of esophageal cancer in Henan Province,Zhengzhou 450052,Henan China;3.Xinxiang Medical College,Xinxiang 453003,Henan China);Morphology Changes of Collagen Fibers in Rats Heart in Electronmicroscope under Different Exercise Loads[J];Journal of Beijing Sport University;2008-10
5 YAN Yi,XIE Min-hao,LI Sheng-wei(Beijing Sport University,Beijing 100084,China);Model of Rats' Decreasing Serum Testosterone Due to Five-week Interval Anaerobic Swimming[J];Journal of Beijing Sport University;2009-02
6 LI Li1,CHANG Bo2 (1.PG Department of Jiaying University,Meizhou 514015,Guangdong China;2.Department of Sports Physiology Biochemistry,Shenyang Physical Education Institute,Shenyang 110032,Liaoning China);Research on the Preventive Effect of Aralia Elata on the Impairment of Renal Function Following Overtraining in Rats[J];Journal of Beijing Sport University;2009-04
7 Yang Ke 1,Li Yang 1,Li Feng 1,Zhao Dan 1,Zhao Xuejian 1,Pei Haihong 2,Chen Yanping 3,Ma Xingyuan 3 (1 Dept.of Reproductive Pathophysiology,NBUMS ChangChun,130021;\ 2\ Dept. of Physical Exercise,NBUMS;\ 3\ Dept. of Natural Medicine,NBUMS) 〔;Effects of PDS on exercise-induced low serum testosterone in rats[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;2000-02
8 WANG Zhi-juan~1,WANG Yun-hong~1,LIANG Lei~1,ZHAO Ming-hua~1,WANG Chao~1,HE Gang~1,ZHANG Lu-fen~21.Capital Institute of Physical Education,Beijing 100088,China;2.Beijing University of Traditional Medicine,Beijing 100000,China.;On the Effects of Moxibustion Shenshu on the Resistant Ability of Rats for Exercise-induced Fatigue[J];Journal of Capital Institute of Physical Education;2006-03
9 DONG Kun 1 , WANG Da-peng 1 (1. Department of Physical Education, Yanshan University, Qinhuangdao, Hebei 066004, China);Effects of exercise on apoptotic gene in myocardium[J];Journal of Yanshan University;2005-06
10 Wang Mi,Xu Mingrong,Yang Ke,et al (Pathology Department of Guangxi Hygienic Administration College,Nanning,530021 China);EFFECT OF PANAXADIOL SAPONINS ON ANTI-OXIDIZATION AND IMMUNOLOGIC REGALATION IN LONG-TERM SWIMMING TRAINING RATS[J];Journal of Guangxi Medical University;2001-04
China Proceedings of conference Full-text Database 1 Hits
1 Liu Jian hua Changbo 1.P.E.Department of Weifang College,Shandong 261061 2.Shenyang Sports College,Liaoning 110032;The Influence of Overtraining on the Free Calcium in the Rats'Cardiac Muscle Mitochondria[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 SHI Qing De, ZHANG Yong *, CHEN Jia Qi and LIU Shu Sen ** ( Tianjin Research Institute of Sports Medicine, Tianjin 300381, China; ** State Key Laboratory of Biomembrane & Membrane Biotechnology, Institute of Zoology, the Chine;Electron Leak Causes Proton Leak in Skeletal Muscle Mitochondria in Exercise induced Fatigue[J];ACTA BIOCHIMICA ET BIOPHYSICA SINICA;1999-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved