Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease》 2017-10
Add to Favorite Get Latest Update

Impact of Danshen Injection Combined with Metoprolol Tartrate on Patients with Unstable Angina Pectoris

REN Xiao-long;Department of Internal Medicine,the second People's Hospital of Shaanxi Province;  
Objective To investigate the impact of danshen injection combined with metoprolol tartrate on patients with unstable angina pectoris( UAP). Methods A total of 95 patients with UAP were selected in the Second People' s Hospital of Shaanxi Province from April 2015 to March 2017,and they were randomly divided into control group( n = 47) and observation group( n = 48). Patients of control group received metoprolol tartrate,while patients of observation group received metoprolol tartrate combined with danshen injection; both groups continuously treated for 4 weeks. Clinical effect,serum levels of s ICAM-1 and MMP-9,quality of life( QOL) before and after treatment,and incidence of adverse reactions during the treatment were compared between the two groups. Results The total effective rate of observation group was statistically significantly higher than that of control group( P 0. 05). No statistically significant differences of serum levels of s ICAM-1 or MMP-9 was found between the two groups before treatment( P 0. 05),while serum levels of s ICAM-1 and MMP-9 of observation group were statistically significantly lower than those of control group after treatment( P 0. 05). No statistically significant differences of QOL score was found between the two groups before treatment( P 0. 05), while QOL score of observation group was statistically significantly higher than that of control group after treatment( P 0. 05). No statistically significant differences of incidence of adverse reactions was found between the two groups during the treatment( P 0. 05). Conclusion Danshen injection combined with metoprolol tartrate has certain clinical effect in treating patients with UAP, can effectively reduce the serum levels of s ICAM-1 and MMP-9,improve the quality of life,and is relatively safe.
【CateGory Index】: R541.4
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved