Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Shenyang Pharmaceutical University》 2003-02
Add to Favorite Get Latest Update

Effects of the Huanglian Jiedu Decoction on acute cerebral ischemia and hypoxia in mice

XU Jing-hua 1, YU Qing-hai 1, CAI Shuang 2, WANG Shuo 1 (1.School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; 2.The First Clinical College, China Medical University, Shenyang 110001, China)  
Objective To study the effects of the Huanglian Jiedu Decoction (HLJDD) on acute cerebral ischemia and hypoxia in mice.Methods Some experiments,including bilateral common carotid artery occlusion,hypoxia induced by NaNO 2 and KCN,closed normobaric hypoxia,were used in mice.Results The survival time in the mice subjected to bilateral common carotid artery occlusion or treated with NaNO 2 (800 mg/kg) was significantly prolonged by the HLJDD.The sleeping latency induced by KCN ( 4.5 mg/kg) in mice was not affected by the HLJDD (2.0,4.0 and 8.0 g/kg,ig),but the sleeping duration was significantly shortened by the HLJDD (2.0,4.0 and 8.0 g/kg,ig).The speed of consuming oxygen in mice under the condition of closed normobaric hypoxia was not affected by the HLJDD (2.0,4.0 and 8.0 g/kg,ig),while the survival time in mice was significantly prolonged by the HLJDD due to improving the ability of using oxygen.Conclusions The results show that the HLJDD has some effects on the acute cerebral ischemia and hypoxia.
【Fund】: 辽宁省教育厅高等学校科学研究资助项目 (2 0 1 5 2 2 2 8)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 YU Yuan-yuan,WANG Bo-chu,PENG Liang,WANG Jing-bo,ZENG Chen(Key Laboratory for Biomechanics and Tissue Engineering Under the State Ministry of Education,College of Bioengineering,Chongqing University,Chongqing 400030,China);Advances in Pharmacological Studies of Coptis Chinesis[J];Journal of Chongqing University(Natural Science Edition);2006-02
2 HE Xiao-jing~1,ZHAO Li-mei~1,LIU Yu-lan~2(1.The Second Affiliated Hospital of China Medical University,Shenyang 110004,China;2.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);The protective effect of Borneol on experimental cerebral ischemia[J];Journal of Guangdong College of Pharmacy;2006-02
3 WANG Xin~1 Ju Yang~2 Luo Qin~2 DANG Yue-lan~3 1.Department of Ultrasound,the Second Hospital of Lanzhou University; 2.Department of Pharmacy,the Second Hospital of Lanzhou University,Lanzhou 730030,China; 3.School of Pharmacy,Lanzhou University,Lanzhou 730000,China;Antihypoxic effect of total glucosides of Acanthopanax giraldii Harms and its mechanism[J];Journal of Lanzhou University(Medical Sciences);2008-04
4 QIAO Xiao-li1,XIAO Xue-feng1*,GAO Lan1,ZHANG Jun-ping2,DU Wu-xun3,LI Cun-yu1(1.Tianjin University of TCM,Tianjin 300193,China;2.First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;3.Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300150,China);Study on the Pharmacokinetics of Jasminoidin in Huanglianjiedu Decoction in Rats with Ischemic Cerebrovascular Disease[J];Lishizhen Medicine and Materia Medica Research;2008-10
5 WANG Jing,PENG Yun-ru,DAI Yue,et al(Pharmacology Section of Traditional Chinese Medicine,China Pharmacy University,Nanjing,Jiangsu,210029);Protective and Anti-coagulation and Anti-thrombus Effects of Tongnaoshuluo Capsule on Cerebral Ischemia and Hypoxia[J];Yunnan Journal of Traditional Chinese Medicine and Materia Medica;2007-05
6 YUAN Zheng-zhong1,ZHU Ling-qun2,PANG He2,SHAN Ze-song1,WANG Shuo-ren2,GAO Yong-hong2,NIU Fu-ling2(1.First Affiliated Hospital of Wenzhou Medical College,Wenzhou 325000,China;2.Key Laboratory of Chinese Internal Medicine of Ministry of Education,Dongzhimeng Hospital,Beijing University of Chinese Medicine,Beijing 100700,China);Protective action of effective components of Huanglian Jiedu decoction on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells[J];China Journal of Chinese Materia Medica;2007-03
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Zhang Mingfa ( Dept. of Pharmacology, Shanxi Academy of Traditional Chinese Medicine, Xian 710003);ANTI-ANOXIC EFFECTS OF BERBER1NE IN INTACT MICE[J];Chinese Pharmacological Bulletin;1991-01
2 WU Jun-Fang;SHI Yi-Ju; LIU Tian-Pei(Department of Pharmacology,Nanjing Medical University,Nanjing 210029;Department of Pharmacology,Tai'an Medical College,Tai'an 271000);Protective effcts of berberine on cerebral ischemia in mice and rats[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;1995-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Chen Guoliang, Ye Shoushan, Liu Jajun, et al AnHui Institute of medical sciences, Hefei 230061;Observation of antibacterial effect of JinDiLan tablet in infected mice body[J];Anhui Medical Journal;2002-05
2 HAN Hui, WU Li-min, TU Jin-wen, HAN Ming-xiang (Hubei Chinese Medical College, Wuhan 430061,China);Studying the effect of shenxiongqin injection in reducing the content of ET-1,TNF-α,IL-1β of focal cerebral infarction in rats[J];Anhui Medical and Pharmaceutical Journal;2005-01
3 Wang Jian,Hu Jianpeng,Wu Huaqiang,Xu Guansun,Li Jing (Anhui College of TCM,Hefei 230038);THERAPEUTIC EFFECT OF NAOLUOTONG TREATMENT ON QI DEFICIENCY AND BLOOD STASIS OF CEREBRAL ISCHEMIA IN RATS[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1999-05
4 LI Ping,ZHANG Mei (Dept.of TCM,Anhui Provincial Hospital,Anhui Hefei 230001,China);EFFECTS OF ASTRAGALUS ON APOPTOSIS RELATED GENE EXPRESSION IN RATS AFTER CEREBRAL ISCHEMIA[J];Journal of Anhui Traditional Chinese Medical College;2001-04
5 QING Fa-ji,YANG Xing-song,ZHAO Hua-qing,LIN Ze-lian(Anhui Province Dingyuan County Hospital of Traditional Chinese Medicine,Anhui Dingyuan 233200,China);Clinical Observation on 48 Cases with Intracerebral Hemorrhage Treated by Jiawei Huanglian Jiedu Decoction[J];Journal of Anhui Traditional Chinese Medical College;2005-05
6 ZHENG Hao(College of Life Science,Northwest A & F University,Yangling 712100,China);Advances of Research And Development of Pueraria Radices[J];Amino Acids & Biotic Resources;2006-02
7 XIE Xiang-lin,QU Shao-chun,LI Chun-yang,YANG Shi-jie (Department of Pharmacology,School of Basic Medical Sciences, Jilin University,Changchun 130021 China) [;Effects of Guanmaining on brain-blood flowing volume and cerebrovascular resistance in dogs[J];;2001-02
8 WANG Xiu hua 1,LI Hong 1,WEN Ke 2,YANG Shi jie 1 (1. Department of Pharmacology, School of Basic Medical Sciences, Jilin University, Changchun 130021,China;2. Department of Pharmacology, Tianjin University of Medical Sciences,Tianjin 300070,China);Effect of anti-cerebral ischemia of gross saponin from tribulus terrestris[J];Journal of Jilin University of (Medicine Edition);2004-01
9 LIU Fen~(1,2),LIU Jie~2,CHEN Xia~(1),L Wen-wei~1,ZHENG Jian-zhong~1(1.Department of Pharmacology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China;2.Experimental Center of Functional Sciences,School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Effect of oxymatrine on inflammation and its mechanism[J];Journal of Jilin University of (Medicine Edition);2005-05
10 HT5SS][KH2D][WT5BZ]LI Su ting,et al [WT5BX](Department of Biochmistry ,Chengde Medical College, Hebei Chengde 067000,China)[KH2D][WT5HZ];THE PROTECTION OF TOTAL FLAVONID FROM STEMS AND LEAVELS OF SCUTELLARIA BAICAL ENSIS AGAINST BRAIN ANOXIA[J];JOURNAL OF CHENGDE MEDICAL COLLEGE;2000-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 DING Yi-wei,Check: GUO Jian-wei,MA Cong Navy Total Hospital,Beijing,China,100048;Investigation on New Antibacterials From Effective Compontents of Chinese Herbs[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2009-06
2 YANG Tao,HAO Xiao-yuan,PENG Yan-gu(TCM University of Hunan,Changsha,Hunan 410007,China);Progress of Chinese drugs on anti-lesion mechanism in vascular endothelial cells[J];Journal of Traditional Chinese Medicine University of Hunan;2009-01
3 WANG Cheng,LI Yu-shu,WANG Ping,et al (Department of Pharmaceutics,The First Clinical College,Jilin University,Changchun 130021,China);Protective effects of gross saponins tribulus terrestris on acute incomplete cerebral ischemia[J];Journal of Harbin Medical University;2008-05
4 Long Wei,Ma Shitang,Liu Peixun~*,Yu Jie,Xu Yang,Hong Ge and Li Xinru (Institute of Radiation Medicine,Chinese Academy of Medicine Science,Peking Union Medical College,Tianjin,300192, China);The multi-target research on the material basis of anti-inflammation effect in HLJD[J];Computers and Applied Chemistry;2009-07
5 ZHANG Xu, QIAO Ji-ying, ZHANG Rong, WEI Zhi-chao, CAI Juan (Department of Immunology and Pathogenic Biology, Medical School of Xi'an Jiaotong University, Xi'an 710061, China);In Vitro Antiprotozoal Effects of Brucea javanica,Coptis chinensis, Radix pulsatillae and Arecae on Blastocystis hominis[J];Journal of Tropical Medicine;2007-11
6 CHENG Kang, FANG Tai -hui, ZHAO-Ya, ZHU-Le, WEI Shao-min (1. Nanjin University of Traditional Chinese Medicine, Nanjin 210029, China; 2. Shanghai Jahwa United Co. Ltd.,Shanghai 201702,China );Experiment study of "Qinyanruyu Decotion" on curing acne vulgaris[J];Detergent & Cosmetics;2007-06
7 Zheng Xiao-wei,Zhou Li-ming(Department of Pharmacology,Preclinical and Forensic Medical College,Sichuan University,Chengdu 610041);Effect of borneol on reverse the multidrug resistance in cancer[J];Sichuan Journal of Physiological Sciences;2007-03
8 FAN Yan-jun,SHI Jun-ying(Shandong University of Traditional Chinese Medicine,Ji′nan 250355);Research progress of compound salvia tablets in the last five years[J];Qilu Pharmaceutical Affairs;2009-04
9 WANG Yi-ping,HE Shan,WU Yu-juan(College of Pharmacy,Southwest Jiaotong University,Emei 614202,China);Study on the Trace Elements of Emei Coptis chinensis[J];Lishizhen Medicine and Materia Medica Research;2007-05
10 XU Pei-hu,GAO Yuan,ZHANG Xue-qiong,ZHANG Liang,XU Ke(Department of Chemical Engineering,Wuhan University of Technology,China);Purification Technology of Total Alkaloids from Rhizoma Coptidis[J];Lishizhen Medicine and Materia Medica Research;2007-12
China Proceedings of conference Full-text Database 1 Hits
1 CHENG Kang Zhao-ya Zhu-le WEI Shao-min (Shanghai Jahwa United Co.Ltd);Experiment study of ‘Qinyanruyu Decotion’on curing acne vulgaris[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Fang Kunquan(Dept. of Pharmacology);Antagonistic Effects of Sophoramine on Experimental Arrhythmias[J];Journal of The Fourth Military Medical University;1987-01
2 Yang Xiaomin, Zhao Dehua and Sheng Baoheng. Department of Pharmacology, Fourth Military Medical College, Xi-an;TOXIC EFFECT OF LIDOCAINE ON THE ACUTE ISCHEMIC HEART OF RABBIT AND THE ANTAGONISTIC ACTION OF L-4-THIAZOLIDINE CARBOXYLIC ACID[J];Medical Journal of Chinese People's Liberation Army;1985-02
3 CHEN Qi-Ming and XIE Ming-Zhi (Institute of Materia Medica, Chinese Academy of Medieval Sciences, Beijing);EFFECTS OF BERBERINE ON BLOOD GLUCOSE REGULATION OF NORMAL MICE[J];Acta Pharmaceutica Sinica;1987-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved