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《Journal of Practical Traditional Chinese Internal Medicine》 2018-07
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Randomized Controlled Study of Bushen Tongbi Decoction(补肾通痹汤) Combined with Western Medicine in Treating(Kidney Yang Deficiency and Cold Coagulation Block/肾阳亏虚寒凝痹阻)Gubi

WANG Hao;CUI Lijian;ZHOU Changchun;AN Yufang;Orthopedics Department of Heilongjiang Medical College of Traditional Chinese Medicine;  
[Objective] To observe the curative effect of Bushen Tongbi decoction combined with western medicine in treating(Kidney Yang deficiency and cold coagulation block)Gubi.[Method] A randomized parallel control method was used to randomly divide 120 hospitalized patients into two groups according to the medical record number.There were 60 patients in the control group.Celecoxib,0.2 g/time,2 times/d; sulfasalazine,1 g/time,2 times/d.There were 60 patients in the treatment group.Bushen Tongyu decoction(epimedium30 g,mature rehmannia glutinosa,cornel,eucommia,achyranthes each 30 g,earthworm one,rhizome of drynaria,chuanxiong rhizome,angelica,futokadsura stem,mulberry twigs each 15 g,licorice root 10 g).1 dose/d,decoction 150 mL,Oral in the morning and evening.Western medicine treatment was the same as the control group.Continuous treatment for 10 days was a course of treatment.The study would observe clinical symptoms,TCM symptom scores,erythrocyte sedimentation rate(ESR),high-sensitivity C-reactive protein(hs-CRP),immunoglobulin G(IgG),and adverse reactions.Continuous treatment of 3 courses to determine efficacy.[Result] The treatment group was cured in 2 cases,markedly effective in 16 cases,effective in 37 cases,ineffective in 5 cases,and the total effective rate was 91.67%.The control group was cured in 1 case,markedly in 14 cases,effective in 28 cases,invalid in 17 cases,and the total effective rate was 71.67%.The therapeutic effect of the treatment group was better than that of the control group(P0.01).TCM symptoms scores were significantly lower in both groups(P0.01),treatment group was better than control group(P0.01),ESR,hs-CRP,IgG were improved(P0.01),treatment group improved In the control group(P0.01).[Conclusion] Bushentongyu decoction combined with western medicine treatment of(Kidney Yang deficiency and cold coagulation block) Gubi has satisfactory effect and no serious adverse reactions.it is worth promoting.
【CateGory Index】: R593.23
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