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《Journal of Practical Traditional Chinese Internal Medicine》 2018-07
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Treatment of Diabetic Constipation(Yinkui Rejie/阴亏热结) with Zengye Runchang Decoction(增液润肠汤) combined with Western Medicine Random Parallel Control Study

JI Yufan;Digestive Department of Dengfeng Hospital of Traditional Chinese Medicine;  
[Objective] To observe the therapeutic effect of Zengye Runchang decoction(增液润肠汤)combined with western medicine on diabetic constipation(Yinkui Rejie).[Methods] Random parallel control method was used to divide 118 outpatients into two groups according to the sequence number,diet and exercise plan,control blood sugar,drink more water,eat more vitamin and cellulose vegetables(silk gourd and celery); general exercise,emphasis on strength of abdominal muscle strength,and more squat and hip flexion Abdominal movement.In the control group,50 cases of mecobalamin,1 tablets/times,3 times/d; domperidone,1 tablets/times,3 times/d; lactulose,1 bottles/times,1 times/d; enema glycerini,1 Zhi/times,and severe constipation.In the treatment group,50 cases of Zengye Runchang decoction(Xuanshen 40 g,Maidong,Yuliren,Heshouwu,Shengdihuang each 15 g,Danggui,Shaoyao each 9 g,Huomaren 15 g,Gancao 3 g,Muxiang6 g),400 mL,1 doses/d,morning and evening; western medicine was treated with the control group.Continuous treatment for 1 weeks was the 1 course of treatment.Clinical symptoms,constipation disappearance time and adverse reactions were observed.The 1 course of treatment(1 weeks) was treated and the curative effect was determined.The recurrence rate was observed for 4 weeks.[Results] in the treatment group,26 cases were cured,32 cases were effective,1 cases were invalid,the total effective rate was 98.30%,14 cases were cured,37 cases were effective,8 cases were invalid,the total effective rate was 86.44%,the curative effect of the treatment group was better than the control group(P0.05).The disappearance time of constipation was shorter in the treatment group than in the control group(P0.01).After 4 weeks of follow-up,the recurrence rate in the treatment group was 15.38% lower than that in the control group 28.57%(P0.05).[Conclusion]Zengye Runchang decoction combined with western medicine in the treatment of diabetic constipation(Yinkui Rejie) has satisfactory curative effect,no serious adverse reactions,and is worthy of promotion.
【CateGory Index】: R587.1
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