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《Reproduction and Contraception》 1999-02
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Significance of Increased TNF-α and IL-6 in Seminal Plasma Induced by CT UU Infection in Infertility

Hu Tao; Wang Hai-yan; Gao Mei-hua;Feng Xian-qi; Wang Yun-ping(Department of Immunology,Binzhou Medical college, Binzhou. 156603 )  
An examination was made of IL-6 and TNF-α in seminal plasma and DNA of chlamydial trachomatis (CT) and U. urealyticum in genital tract of infertile couple, using ELISA and PCR respectively. The results showed there was an increase of TNF-α and IL-6 and parallel relation between CT and UU infection and TNF-α and IL-6 experssion. Infection and cytokine expression not only affect sperm density,motility rate and liquefiaction but also participated in inflammatory lesion of genital organs. These suggested cytokines and CT,UU infection participated in infertile process.
【CateGory Index】: R711.6
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